Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R. T. Windh"'
Publikováno v:
Endocrinology. 129:959-964
The purpose of the present study was to determine the relative ontogeny of mu- and kappa-opiate receptor control of the hypothalamo-pituitary-adrenal (HPA) axis in rats. The ability of the mu-agonist morphine and the kappa-agonist U-50,488 to stimula
Publikováno v:
The Journal of biological chemistry. 276(52)
Sphingosine 1-phosphate (S1P) exerts a variety of actions as a second messenger or as an agonist that binds to one or more members of the Edg family of G protein-coupled receptors. By using human embryonic kidney 293 cells, we show that S1P activates
Publikováno v:
The Journal of biological chemistry. 274(52)
Many of the alpha subunits of heterotrimeric GTP-binding regulatory proteins (G proteins) are palmitoylated, a modification proposed to play a key role in the stable anchorage of the subunits to the plasma membrane. Palmitoylation of alpha subunits f
Autor:
R T, Windh, C M, Kuhn
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(3)
The developmental changes in mu opiate receptor-mediated antinociception and coupling to guanyl nucleotide binding proteins were studied in the rat. ED50 values for morphine- and sufentanil-induced antinociception were determined in the paw-lift assa
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(3)
The ontogeny of tolerance to mu opiate antinociception and the behavioral and endocrine profiles of the opiate withdrawal syndrome were studied in rats. Animals were treated with saline or an increasing dose regimen of morphine for 5 days (5-25 mg/kg
Publikováno v:
Neuropharmacology. 31(2)
The present study investigated the effect of chronic administration of a kappa opioid receptor agonist on the function of kappa and mu opioid, serotonergic and cholinergic regulation of secretion from the hypothalamo-pituitary-adrenal axis in neonata