Zobrazeno 1 - 10
of 66
pro vyhledávání: '"R. T. Smolenski"'
Autor:
M. A. Zabielska-Kaczorowska, A. E. Bogucka, K. Macur, P. Czaplewska, S. A. Watson, F. Perbellini, C. M. Terracciano, R. T. Smolenski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract A special in vitro model maintained with ultrathin cardiac slices with a preserved architecture, multi-cellularity, and physiology of the heart tissue was used. In our experiments, we performed label-free quantitative SWATH-MS proteomic anal
Externí odkaz:
https://doaj.org/article/f1f3f5eef3f24913ba736d3171ff4ce3
Autor:
Wlodzimierz Buczko, Agnieszka Leszczynska, Barbara Sitek, Ewa Chabielska, R. T. Smolenski, Tomasz W. Kaminski, Karol Kramkowski, Bartosz Proniewski, U. Rykaczewska, Agnieszka Zakrzewska, Kamil Przyborowski, Stefan Chlopicki
Publikováno v:
Platelets. 27:245-253
The mechanisms underlying nitrite-induced effects on thrombosis and hemostasis in vivo are not clear. The goal of the work described here was to investigate the role of xanthine oxidoreductase (XOR) in the anti-platelet and anti-thrombotic activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d013159e2e7aa673fc93ec3a31555259
https://doi.org/10.3109/09537104.2015.1083545
https://doi.org/10.3109/09537104.2015.1083545
Autor:
Iwona Pelikant-Malecka, R. T. Smolenski, Mariola Olkowicz, Ewa M. Slominska, Małgorzata Swiatkowska-Freund, Ewa Kaniewska, Krzysztof Preis, Alicja Sielicka, Magdalena M. Gorska, Zofia Pankrac
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 33:342-346
Mechanisms of free radical injury involve chemical modification of proteins, lipid derivatives and nucleic acids and consequent loss of its function. However, specific targets and exact sequence of events has not been fully clarified. We determined w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8c32e93ab17d8f61cc492d4fd3cbef
https://doi.org/10.1080/15257770.2014.898069
https://doi.org/10.1080/15257770.2014.898069
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 35(10-12)
Previous studies demonstrated that human endothelial cells were capable to phosphorylate 4-pyridone-3-carboxamide-1β-D-ribonucleoside (4PYR) to monophosphate (4PYMP) and formed another metabolite-an analog of NAD (4PYRAD). Elevated levels of 4PYMP a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8414f961cc2b84ad3402c7254aa4c3
https://pubmed.ncbi.nlm.nih.gov/27906624
https://pubmed.ncbi.nlm.nih.gov/27906624
Autor:
Robert S. George, Carole Webb, A. Cheetham, Asghar Khaghani, R. T. Smolenski, Emma J. Birks, Magdi H. Yacoub, A. Kelion
Publikováno v:
European Journal of Heart Failure. 15:1035-1043
Aims Dilated cardiomyopathy (DCM) patients have abundant levels of norepinephrine secondary to failure of the norepinephrine transporter uptake mechanism. Little is known about the effects of an LV assist device (LVAD) on cardiac sympathetic innervat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fb1cdaa3cd325e4e130de96b0a1025
https://doi.org/10.1093/eurjhf/hft059
https://doi.org/10.1093/eurjhf/hft059
Autor:
Stefan Chlopicki, Piotr Siondalski, Czesława Orlewska, Ewa M. Slominska, R. T. Smolenski, Magdi H. Yacoub, T. Borkowski
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 29:449-452
Clinical observation in patients with heart disease indicates that reduced activity of AMP deaminase could be protective in heart failure and ischemic heart disease. This study evaluated the effect of 3-[2-(3-carboxy-4-bromo-5,6,7,8-tetrahydronaphthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d60725e4a5348bc9a076a080e9f3d8
https://doi.org/10.1080/15257771003741364
https://doi.org/10.1080/15257771003741364
Autor:
Piotr Siondalski, R. T. Smolenski, Czesława Orlewska, Ada H.Y. Yuen, Magdi H. Yacoub, Ewa M. Slominska, S. Al-Ayoubi, T. Borkowski
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 29:457-460
AMP deaminase could be a potential target for treatment of heart disease but experimental evaluation of this concept is difficult due to limited availability of inhibitors with proven efficiency in biological systems. This study evaluated the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093288a8cbbf903ba3cc3daab91b729a
https://doi.org/10.1080/15257771003741299
https://doi.org/10.1080/15257771003741299
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 25:1125-1128
Endothelial degradation of extracellular nucleotides is known to be an important mechanism in regulation of thrombosis, inflammation and immune response. It is possible that this pathway is a target for pleiotropic drugs such as atorvastatin. We stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c7e81b986c892ba087b582b6d54eb3
https://doi.org/10.1080/15257770600894196
https://doi.org/10.1080/15257770600894196
Autor:
A. H. Y. Yuen, M. Boscoe, R. Lango, K. Suzuki, E. M. Slominska, M. H. Yacoub, R. T. Smolenski
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 24:267-270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da285b3b0fb1e614460b97cb03aed7c5
https://doi.org/10.1081/ncn-200059705
https://doi.org/10.1081/ncn-200059705
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 24:279-282
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb27d4624ddc9b914ed3eca7d71311d5
https://doi.org/10.1081/ncn-200059711
https://doi.org/10.1081/ncn-200059711