Výsledky vyhledávání - "R. T. Mitsuyasu"

Potential use of human stem cell factor as adjunctive therapy for human immunodeficiency virus-related cytopenias

Autor: S A, Miles, K, Lee, L, Hutlin, K M, Zsebo, R T, Mitsuyasu

Publikováno v: Blood. 78:3200-3208

Hematopoietic dysfunction with peripheral cytopenias is a common complication of human immunodeficiency virus (HIV) infection. Symptomatic anemia is the most common cytopenia and occurs in the presence and absence of myelosuppressive drug therapy suc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bc1d7a4895ff96ff18602776056542
https://doi.org/10.1182/blood.v78.12.3200.bloodjournal78123200

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Infection with HIV is associated with elevated IL-6 levels and production

Autor: E C Breen, A R Rezai, K Nakajima, G N Beall, R T Mitsuyasu, T Hirano, T Kishimoto, O Martinez-Maza

Publikováno v: The Journal of Immunology. 144:480-484

Polyclonal B cell activation is commonly observed in AIDS and in infection with HIV. Because IL-6 (B cell stimulatory factor 2) plays an essential role in the differentiation of activated B cells to Ig-secreting cells, and because IL-6 production is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2c8f5e9b205e74ca89abe593a00e78b
https://doi.org/10.4049/jimmunol.144.2.480

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25. A Dose Escalation Study of Cyclophophamide (CTX) to Enhance SB-728-T Engraftment

Autor: Ricky Hsu, J. Lalezari, Trevor Hawkins, Winson Tang, Gary Blick, R. T. Mitsuyasu, Dale Ando, Shelley Wang, David Parks, Edwin DeJesus

Publikováno v: Molecular Therapy. 23:S11

Background: CCR5 modified autologous CD4 cells (SB-728-T) are safe and increases total CD4 counts. The cells traffic to lymphoid tissues and have a selective survival advantage during ART treatment interruption (TI). Additional studies in CCR5 D32 he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccb71f6a193e2f3e7a01b9749f79f8e
https://doi.org/10.1016/s1525-0016(16)33629-2

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AIDS vaccine 2001: looking to the future

Autor: R T, Mitsuyasu

Publikováno v: African health sciences. 1(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eda9038d558b5ae0df754f85bf9f1a10
https://pubmed.ncbi.nlm.nih.gov/12830816

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Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects

Autor: R T, Mitsuyasu, P A, Anton, S G, Deeks, D T, Scadden, E, Connick, M T, Downs, A, Bakker, M R, Roberts, C H, June, S, Jalali, A A, Lin, R, Pennathur-Das, K M, Hege

Publikováno v: Blood. 96(3)

We have genetically engineered CD4(+) and CD8(+) T cells with human immunodeficiency virus (HIV) specificity by inserting a gene, CD4zeta, containing the extracellular domain of human CD4 (which binds HIV env) linked to the zeta (zeta) chain of the T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71862cdfdb9f3f3399a310f1db79f470
https://pubmed.ncbi.nlm.nih.gov/10910888

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Autor: R T, Mitsuyasu

Publikováno v: Oncology (Williston Park, N.Y.). 14(6)

Kaposi's sarcoma (KS) is the most common malignancy associated with the acquired immunodeficiency syndrome (AIDS). Recent years have witnessed a decline in the overall incidence of AIDS-related KS, as well as a greater understanding of the pathogenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b15908f01b55c1793840e4ee3eace40
https://pubmed.ncbi.nlm.nih.gov/10887636

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Activity of the soft gelatin formulation of saquinavir in combination therapy in antiretroviral-naive patients. NV15355 Study Team

Autor: R T, Mitsuyasu, P R, Skolnik, S R, Cohen, B, Conway, M J, Gill, P C, Jensen, J J, Pulvirenti, L N, Slater, R T, Schooley, M A, Thompson, R A, Torres, C M, Tsoukas

Publikováno v: AIDS (London, England). 12(11)

A Phase II, open-label, randomized, parallel-arm, multicentre trial to compare the antiviral activity and safety of two formulations of saquinavir (SQV), soft gelatin (SQV-SGC) and hard gelatin (SQV-HGC) capsules, in combination with two nucleoside r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::325d535751b2976575b845a794049c24
https://pubmed.ncbi.nlm.nih.gov/9708399

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AIDS Clinical Trials Group Study 094: a phase I/II trial of ABV chemotherapy with zidovudine and recombinant human GM-CSF in AIDS-related Kaposi's sarcoma

Autor: P S, Gill, R T, Mitsuyasu, T, Montgomery, J, Huang, S, Cabriales, M, Testa, B M, Espina, A M, Levine, S A, Miles

Publikováno v: The cancer journal from Scientific American. 3(5)

To define the maximum tolerated dose of doxorubicin when combined with fixed doses of bleomycin, vincristine, zidovudine, and recombinant human granulocyte macrophage colony-stimulating factor (rhGM-CSF) in patients with advanced AIDS-related Kaposi'

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88312fcde892b79607271fc3cbbb6ae2
https://pubmed.ncbi.nlm.nih.gov/9327148

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Pathogenesis of AIDS--related Kaposi's sarcoma

Autor: C, Emmanoulides, S A, Miles, R T, Mitsuyasu

Publikováno v: Oncology (Williston Park, N.Y.). 10(3)

The occurrence of Kaposi's sarcoma (KS) in patients with HIV infection is more than 7,000 times higher than in the non-HIV infected population. The reason for this association is unclear but may involve decreased immune surveillance as a result of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7dce877063fa5968a28e51222e620bd
https://pubmed.ncbi.nlm.nih.gov/8820448

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