Zobrazeno 1 - 10
of 112
pro vyhledávání: '"R. T. Jensen"'
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 316(2)
Rat pancreatic acinar cells possess only the p21-activated kinase (PAKs), PAK4 of the group II PAK, and it is activated by gastrointestinal hormones/neurotransmitters stimulating PLC and by a number of growth factors. However, little is known general
Publikováno v:
Endoscopy. 42:664-671
Well differentiated neuroendocrine tumors (NETs) of the stomach (gastric carcinoid tumors) are observed more often, with a tenfold increase in the US in the last 30 - 35 years, and the prognosis has improved greatly in that time. Nowadays most carcin
Publikováno v:
Journal of cellular biochemistry. 116(1)
Recent studies report the Src-family kinases (SFK's) are important in a number of physiological and pathophysiological responses of pancreatic acinar cells (pancreatitis, growth, apoptosis); however, the role of SFKs in various signaling cascades imp
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 262:G461-G469
On the basis of opioid-stimulated contraction of dispersed gastric smooth muscle cells it has been suggested that these cells possess opioid receptors of three subtypes: kappa (kappa), mu (mu), and delta (delta). We have used selective peptidase-resi
Autor:
N. Y. Jiang, Jacques-Pierre Moreau, Jia-Ming Qian, Sun Hyuk Kim, H. Frucht, David H. Coy, R. T. Jensen, Lu-Wa Wang, Jaw-Town Lin
Publikováno v:
Journal of Biological Chemistry. 266:16441-16447
During a search for possible cyclization points in shortened, potent bombesin agonists and antagonists, it was found that the joining of amino acid residues in positions 6 and 14 by various means resulted in retention of significant binding affinity
Autor:
Aldo Torsoli, L D'Arpino, G. Delle Fave, D. H. Coy, Carola Severi, Vittorio Erspamer, R. T. Jensen
Publikováno v:
Scopus-Elsevier
Recent studies suggest that different subtypes of receptors may mediate the action of various bombesin-related peptides in different tissues. In the present study the ability of bombesin and its structurally related peptides [litorin, gastrin-releasi
Autor:
S, Bashir, F, Gibril, J V, Ojeaburu, B, Asgharian, L K, Entsuah, G, Ferraro, P, Crafa, C, Bordi, R T, Jensen
Publikováno v:
Alimentary pharmacologytherapeutics. 16(7)
Chronic hypergastrinaemia causes gastric enterochromaffin cell proliferation and carcinoid tumours. The only reliable means to diagnose enterochromaffin cell changes/carcinoids is by biopsy.To assess whether serum histamine, chromogranin A or seroton
Autor:
T W, Moody, R T, Jensen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(3)
The effects of cholecystokinin (CCK) antagonists on small cell lung cancer (SCLC) cells were investigated. CI-988, L-365,260, and L-364,718 inhibited specific (125)I-CCK-8 binding to NCI-H209 cells with IC(50) values of 5, 2, and 200 nM. ([R-(R*,R*)]
Autor:
V D, Corleto, B, Annibale, F, Gibril, S, Angeletti, J, Serrano, D J, Venzon, G, Delle Fave, R T, Jensen
Publikováno v:
Alimentary pharmacologytherapeutics. 15(10)
Proton pump inhibitors are potent acid suppressants which, at normal doses, can result in hypergastrinaemia in patients with idiopathic oesophageal reflux disease and in the control of symptoms in most patients with gastrinomas. Therefore, their use
Autor:
C, Bordi, V D, Corleto, C, Azzoni, S, Pizzi, G, Ferraro, F, Gibril, G, Delle Fave, R T, Jensen
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(5)
Carcinoid tumors were identified in the antro-pyloric mucosa of four patients with multiple endocrine neoplasia type 1 (MEN-1)/Zollinger-Ellison syndrome, accounting for 8.7% of 46 patients with this condition examined by endoscopy and histology. In