Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R. T. H. van Welie"'
Publikováno v:
van Welie, R T H, van Dijck, R G, Vermeulen, N P & van Sittert, N J 1992, ' Mercapturic acids, protein adducts, and DNA adducts as biomarkers of electrophilic chemicals ', Critical Reviews in Toxicology, vol. 22, no. 5-6, pp. 271-306 . https://doi.org/10.3109/10408449209146310
The possibilities and limitations of using mercapturic acids and protein and DNA adducts for the assessment of internal and effective doses of electrophilic chemicals are reviewed. Electrophilic chemicals may be considered as potential mutagens and/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86737cd0590cf1cf9d5f993d4099a65
https://doi.org/10.3109/10408449209146310
https://doi.org/10.3109/10408449209146310
Publikováno v:
International Archives of Occupational and Environmental Health, 63(3), 169-73. Springer Verlag
van Welie, R T H, van Duyn, P & Vermeulen, N P 1991, ' Environmental and biological monitoring of non-occupational exposure to 1,3-dichloropropene ', International Archives of Occupational and Environmental Health, vol. 63, no. 3, pp. 169-73 . https://doi.org/10.1007/BF00381564
van Welie, R T H, van Duyn, P & Vermeulen, N P 1991, ' Environmental and biological monitoring of non-occupational exposure to 1,3-dichloropropene ', International Archives of Occupational and Environmental Health, vol. 63, no. 3, pp. 169-73 . https://doi.org/10.1007/BF00381564
Voluntary bystanders, simulating a situation of non-occupational exposure to Z- and E-1,3-dichloropropene (Z- and E-DCP), were exposed during field application of this nematocide in the Dutch flower-bulb culture. Environmental monitoring revealed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b6777573384cc0291ddf8e71fc6d22
https://doi.org/10.1007/bf00381564
https://doi.org/10.1007/bf00381564
Autor:
Nico P. E. Vermeulen, E. K. Lamme, P. Jager, R. T. H. van Welie, B. L. M. Van Baar, P. van Duyn
Publikováno v:
van Welie, R T H, van Duyn, P, Lamme, E K, Jäger, P, van Baar, B L & Vermeulen, N P 1991, ' Determination of tetrahydrophtalimide and 2-thiothiazolidine-4-carboxylic acid, urinary metabolites of the fungicide captan, in rats and humans ', International Archives of Occupational and Environmental Health, vol. 63, no. 3, pp. 181-6 . https://doi.org/10.1007/BF00381566
International Archives of Occupational and Environmental Health, 63(3), 181-6. Springer Verlag
International Archives of Occupational and Environmental Health, 63(3), 181-6. Springer Verlag
Capillary gas chromatographic (GC) methods using sulphur and mass selective detection for the qualitative and quantitative determination of tetrahydrophtalimide (THPI) and 2-thiothiazolidine-4-carboxylic acid (TTCA), urinary metabolites of the fungic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fbf60e08c3c03045ac7983b31bb42d
https://hdl.handle.net/1871.1/9249673b-4fcd-490b-aa04-b1cbe527ce67
https://hdl.handle.net/1871.1/9249673b-4fcd-490b-aa04-b1cbe527ce67
Publikováno v:
van Welie, R T H, Mensert, R, van Duyn, P & Vermeulen, N P 1991, ' Identification and quantitative determination of a carboxylic and a mercapturic acid metabolite of etridiazole in urine of rat and man. Potential tools for biological monitoring ', Archives of Toxicology, vol. 65, no. 8, pp. 625-32 . https://doi.org/10.1007/BF02098027
Archives of Toxicology, 65(8), 625-32. Springer Verlag
Archives of Toxicology, 65(8), 625-32. Springer Verlag
Etridiazole, 5-ethoxy-3-trichloromethyl-1,2,4-thiadiazole, was orally administered to rats and human volunteers. Two metabolites of etridiazole were synthesized: 5-ethoxy-1,2,4-thiadiazole-3-carboxylic acid (ET-CA) and N-acetyl-S-(5-ethoxy-1,2,4-thia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c687b7d9033d799bb9236d1fddf5184
https://hdl.handle.net/1871.1/fb450a82-4335-4274-b24e-1129e3e4a229
https://hdl.handle.net/1871.1/fb450a82-4335-4274-b24e-1129e3e4a229
Publikováno v:
Occupational and Environmental Medicine. 48:646-648
A prospective study was performed in the Dutch flower bulb culture to investigate the possible effects of subchronic exposure to the soil fumigant 1,3-dichloropropene (DCP) on liver and kidney function and on glutathione conjugation capacity in blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc45c34befcdca2dd9a877409d43044
https://doi.org/10.1136/oem.48.9.646
https://doi.org/10.1136/oem.48.9.646
Publikováno v:
British journal of industrial medicine, 48(7), 492-8. BMJ Publishing Group
van Welie, R T H, van Marrewijk, C M, Wolff, F A & Vermeulen, N P 1991, ' Thioether excretion in urine of applicators exposed to 1,3-dichloropropene : a comparison with urinary mercapturic acid excretion ', British journal of industrial medicine, vol. 48, no. 7, pp. 492-8 .
van Welie, R T H, van Marrewijk, C M, Wolff, F A & Vermeulen, N P 1991, ' Thioether excretion in urine of applicators exposed to 1,3-dichloropropene : a comparison with urinary mercapturic acid excretion ', British journal of industrial medicine, vol. 48, no. 7, pp. 492-8 .
The excretion of thioethers in urine of applicators occupationally exposed to the soil fumigant 1,3-dichloropropene (DCP) was determined by the thioether assay. The mercapturic acid metabolite of E-1,3-dichloropropene, N-acetyl-S-(E-3-chloropropenyl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ab435ba8633aaf3fbba3d181d300c5
https://research.vu.nl/en/publications/d6719231-d7dd-426d-a604-a2a8c2bfb9da
https://research.vu.nl/en/publications/d6719231-d7dd-426d-a604-a2a8c2bfb9da
Autor:
E.J. Brouwer, Derk H. Brouwer, R. T. H. van Welie, J.A.F. de Vreede, J.J. van Hemmen, Nico P. E. Vermeulen
Publikováno v:
Archives of Environmental Contamination and Toxicology, 1, 20, 1-5
Respiratory occupational exposure to the Z- and E-isomers of 1,3-dichloropropene (DCP) of twelve commercial applicators was assessed. The time-weighted average (TWA) concentrations of DCP ranged from 1.9 to 18.9 mg/m3. On 30% of the observed working
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df38f59b5e4a7bc876c6072cf4188a04
http://resolver.tudelft.nl/uuid:5ca5014d-855d-4cbe-908e-b5eebd092d72
http://resolver.tudelft.nl/uuid:5ca5014d-855d-4cbe-908e-b5eebd092d72
Autor:
R. T. H. van Welie, E. J. Brouwer, Derk H. Brouwer, Nico P. E. Vermeulen, J.J. van Hemmen, P. van Duyn
Publikováno v:
Archives of Environmental Contamination and Toxicology, 20(1), 6-12. Springer New York
van Welie, R T H, van Duyn, P, Brouwer, D H, van Hemmen, J J, Brouwer, E J & Vermeulen, N P 1991, ' Inhalation exposure to 1,3-dichloropropene in the Dutch flower-bulb culture. Part II. Biological monitoring by measurement of urinary excretion of two mercapturic acid metabolites ', Archives of Environmental Contamination and Toxicology, vol. 20, no. 1, pp. 6-12 . https://doi.org/10.1007/BF01065321
van Welie, R T H, van Duyn, P, Brouwer, D H, van Hemmen, J J, Brouwer, E J & Vermeulen, N P 1991, ' Inhalation exposure to 1,3-dichloropropene in the Dutch flower-bulb culture. Part II. Biological monitoring by measurement of urinary excretion of two mercapturic acid metabolites ', Archives of Environmental Contamination and Toxicology, vol. 20, no. 1, pp. 6-12 . https://doi.org/10.1007/BF01065321
A biological monitoring study was carried out in the Dutch flower-bulb culture to determine the relationship between respiratory occupational exposure to Z- and E-1,3-dichloropropene (Z- and E-DCP) and urinary excretion of two mercapturic acid metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e900b33eeb2769e88810110eb0fe8d
https://research.vu.nl/en/publications/5fb93dee-40e6-497a-88db-392d7da97f5b
https://research.vu.nl/en/publications/5fb93dee-40e6-497a-88db-392d7da97f5b
Autor:
R. T. H. van Welie, Nico P. E. Vermeulen, W.H.M. Peters, P.J. van Bladeren, J.J.P. Boogaards, R.M.E. Vos, Ch.T.A. Evelo
Publikováno v:
Vos, R M, van Welie, R T H, Peters, W H, Evelo, C T, Boogaards, J J, Vermeulen, N P & van Bladeren, P J 1991, ' Genetic deficiency of human class mu glutathione S-transferase isoenzymes in relation to the urinary excretion of the mercapturic acids of Z-and E-1,3-dichloropropene ', Archives of Toxicology, vol. 65, no. 2, pp. 95-9 . https://doi.org/10.1007/BF02034933
Archives of Toxicology, 65(2), 95-9. Springer Verlag
Archives of Toxicology, 65(2), 95-9. Springer Verlag
Mononuclear lymphocytes were isolated from the blood of 12 individuals, who had been exposed to the vapour of the soil fumigant 1,3-dichloropropene (DCP). Western blot experiments were performed on the crude lymphocyte homogenates, using a monoclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e231c2534db90ec6cff9e0e190fd51d3
https://pubmed.ncbi.nlm.nih.gov/2059159
https://pubmed.ncbi.nlm.nih.gov/2059159
Publikováno v:
Vrije Universiteit Amsterdam
Journal of Chromatography A, 496(2), 463-71. Elsevier
van Welie, R T H, van Duyn, P & Vermeulen, N P 1989, ' Determination of two mercapturic acid metabolites of 1,3-dichloropropene in human urine with gas chromatography and sulphur-selective detection ', Journal of Chromatography A, vol. 496, no. 2, pp. 463-71 .
Journal of Chromatography A, 496(2), 463-71. Elsevier
van Welie, R T H, van Duyn, P & Vermeulen, N P 1989, ' Determination of two mercapturic acid metabolites of 1,3-dichloropropene in human urine with gas chromatography and sulphur-selective detection ', Journal of Chromatography A, vol. 496, no. 2, pp. 463-71 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d12df141fe230aadd058d4766e7e92
https://hdl.handle.net/1871.1/344d3a83-d870-4922-a465-292d741cb573
https://hdl.handle.net/1871.1/344d3a83-d870-4922-a465-292d741cb573