Zobrazeno 1 - 10
of 421
pro vyhledávání: '"R. Swann"'
Autor:
Adesola T. Bello, Magali H. Sarafian, Elizabeth A. Wimborne, Benita Middleton, Victoria L. Revell, Florence I. Raynaud, Namrata R. Chowdhury, Daan R. van der Veen, Debra J. Skene, Jonathan R. Swann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Bile acids are trans-genomic molecules arising from the concerted metabolism of the human host and the intestinal microbiota and are important for digestion, energy homeostasis and metabolic regulation. While diurnal variation has been demon
Externí odkaz:
https://doaj.org/article/ce39fe2e71344cf991bc20baa6eb30fb
Autor:
Martin Chadwick, Jonathan R. Swann, Frances Gawthrop, Richard Michelmore, Davide Scaglione, Maria Jose-Truco, Carol Wagstaff
Publikováno v:
Food Chemistry: Molecular Sciences, Vol 9, Iss , Pp 100215- (2024)
Lettuce is the most highly consumed raw leafy vegetable crop eaten worldwide, making it nutritionally important in spite of its comparatively low nutrient density in relation to other vegetables. However, the perception of bitterness caused by high l
Externí odkaz:
https://doaj.org/article/841efb6d666b49479612d409d43fc513
Autor:
Martin Chadwick, Jonathan R. Swann, Frances Gawthrop, Richard Michelmore, Davide Scaglione, Maria Jose-Truco, Carol Wagstaff
Publikováno v:
Food Chemistry: Molecular Sciences, Vol 9, Iss , Pp 100226- (2024)
Externí odkaz:
https://doaj.org/article/b91688a268ae4e77bb606f1ff9e844c5
Autor:
Giorgia Caspani, Simon G.D. Ruffell, WaiFung Tsang, Nigel Netzband, Cyrus Rohani-Shukla, Jonathan R. Swann, Wilfred A. Jefferies
Publikováno v:
Pharmacological Research, Vol 207, Iss , Pp 107338- (2024)
Psychedelics have emerged as promising therapeutics for several psychiatric disorders. Hypotheses around their mechanisms have revolved around their partial agonism at the serotonin 2 A receptor, leading to enhanced neuroplasticity and brain connecti
Externí odkaz:
https://doaj.org/article/6e4a88bcdad14aa0b2bdd5a33c924e0c
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Hydrolyzed protein diets are extensively used to treat chronic enteropathy (CE) in cats. However, the biochemical effects of such a diet on feline CE have not been characterized. In this study an untargeted 1H nuclear magnetic resonance spec
Externí odkaz:
https://doaj.org/article/025ada077c354dad9fce699e3f9dbadf
Autor:
Natasa Giallourou, Jason Arnold, Elizabeth T. Rogawski McQuade, Muyiwa Awoniyi, Rose Viguna Thomas Becket, Kenneth Walsh, Jeremy Herzog, Ajay S. Gulati, Ian M. Carroll, Stephanie Montgomery, Pedro Henrique Quintela, Angela M. Faust, Steven M. Singer, Anthony A. Fodor, Tahmeed Ahmad, Mustafa Mahfuz, Esto Mduma, Thomas Walongo, Richard L. Guerrant, R. Balfour Sartor, Jonathan R. Swann, Margaret N. Kosek, Luther A. Bartelt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Giardia lamblia (Giardia) is among the most common intestinal pathogens in children in low- and middle-income countries (LMICs). Although Giardia associates with early-life linear growth restriction, mechanistic explanations for Giardia-asso
Externí odkaz:
https://doaj.org/article/80ad1c0a8c014079ba7ab235aa81ba3b
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 841 (2024)
Affecting approximately 25% of the global population, steatotic liver disease (SLD) poses a significant health concern. SLD ranges from simple steatosis to metabolic dysfunction-associated steatohepatitis and fibrosis with a risk of severe liver comp
Externí odkaz:
https://doaj.org/article/a431fc7bb47440c58f9ecf5cb82772ad
Autor:
Ditte Olsen Lützhøft, Cecilie Bækgård, Elizabeth Wimborne, Ellen Marie Straarup, Karen-Margrethe Pedersen, Jonathan R Swann, Henrik Duelund Pedersen, Kim Kristensen, Line Morgills, Dennis Sandris Nielsen, Axel Kornerup Hansen, Marianne Kronborg Bracken, Susanna Cirera, Berit Østergaard Christoffersen
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0298602 (2024)
The objectives were 1) to characterize a Göttingen Minipig model of metabolic syndrome regarding its colon microbiota and circulating microbial products, and 2) to assess whether ovariectomized female and castrated male minipigs show similar phenoty
Externí odkaz:
https://doaj.org/article/90a2b8f6cca8471cb76ca51ffe9a1c22
Autor:
Guanlan Hu, Catriona Ling, Lijun Chi, Mehakpreet K. Thind, Samuel Furse, Albert Koulman, Jonathan R. Swann, Dorothy Lee, Marjolein M. Calon, Celine Bourdon, Christian J. Versloot, Barbara M. Bakker, Gerard Bryan Gonzales, Peter K. Kim, Robert H. J. Bandsma
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Impaired liver metabolic function is related to mortality in severely malnourished children. Here the authors report a role for the tryptophan-NAD + pathway in reduced hepatic mitochondrial function and liver steatosis in a mouse model of severe maln
Externí odkaz:
https://doaj.org/article/aa11ca067c7a4a78b2f4cd56aa6a91e5
Autor:
Marine P. M. Letertre, Aadra P. Bhatt, Michael Harvey, Jeremy K. Nicholson, Ian D. Wilson, Matthew R. Redinbo, Jonathan R. Swann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The hydrolysis of xenobiotic glucuronides by gut bacterial glucuronidases reactivates previously detoxified compounds resulting in severe gut toxicity for the host. Selective bacterial β-glucuronidase inhibitors can mitigate this toxicity b
Externí odkaz:
https://doaj.org/article/34c9f57a08794c10b4170f32208be4e9