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Treatment of rickets and dyslipidemia in twins with progressive familial intrahepatic cholestasis type 2

Autor: Emily L. Germain-Lee, Sunitha R. Sura

Publikováno v: International Journal of Pediatric Endocrinology
International Journal of Pediatric Endocrinology, Vol 2020, Iss 1, Pp 1-6 (2020)

Background Progressive Familial Intrahepatic Cholestasis Type 2 (PFIC2) is a rare congenital cholestatic liver disease that progresses to end stage liver disease. It is associated with fat soluble vitamin D deficiency rickets and severe dyslipidemia;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9562f5eaa8b4128cdf885d7fe9df0107
http://europepmc.org/articles/PMC7249403

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Studies of styrene, styrene oxide and 4-hydroxystyrene toxicity in CYP2F2 knockout and CYP2F1 humanized mice support lack of human relevance for mouse lung tumors

Autor: G. Cruzan, J. Bus, J. Hotchkiss, R. Sura, C. Moore, G. Yost, M. Banton, S. Sarang

Publikováno v: Regulatory Toxicology and Pharmacology. 66:24-29

Styrene (S) is lung tumorigenic in mice but not in rats. S and its alkene-oxidized metabolite styrene oxide (SO) were not lung toxic in CYP2F2(-/-) [knockout] mice, indicating S-induced mouse lung tumors are mediated through mouse-specific CYP2F2-gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8486b08a8456b08680161a63038b657c
https://doi.org/10.1016/j.yrtph.2013.02.008

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Effects of Ligands on the Mobility of an Active-Site Loop in Tyrosine Hydroxylase as Monitored by Fluorescence Anisotropy

Autor: V. B. Gawandi, Paul F. Fitzpatrick, Giri R. Sura, Mauricio Lasagna, Gregory D. Reinhart

Publikováno v: Biochemistry. 45:9632-9638

Fluorescence anisotropy has been used to monitor the effect of ligands on a mobile loop over the active site of tyrosine hydroxylase. Phe184 in the center of the loop was mutated to tryptophan, and the three native tryptophan residues were mutated to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c735cd1ac17c6be700649d33f74688e1
https://doi.org/10.1021/bi060754b

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Effect of Strontium doping on the Oxygen Diffusion in La 2−x Sr x CuO 4±δ samples Investigated by Oxygen Isotope Back Exchange

Autor: Lukas Keller, Monica Ceretti, Carmelo Prestipino, Ekaterina Pomjakushina, Werner Paulus, Jürg Schefer, K. Conder, R. Sura

Publikováno v: Journal of Physics: Conference Series
Journal of Physics: Conference Series, IOP Publishing, 2012, 340 (1), pp.012110. ⟨10.1088/1742-6596/340/1/012110⟩

International audience; Similar to LaCoO 4.14 , La 2−x Sr x CuO 4±δ shows oxygen diffusion at moderate temperatures. The Oxygen Isotope Back Exchange (OIBE) experiments are done in order to investigate the effect of strontium on the oxygen diffus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84723ae9d5cf3f6949b0335b502f0f2c
https://hal.archives-ouvertes.fr/hal-00802376

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Lymphatics, tertiary lymphoid organs and the granulomas of Crohn's disease: an immunohistochemical study

Autor: R, Sura, J-F, Colombel, H J, Van Kruiningen

Publikováno v: Alimentary pharmacologytherapeutics. 33(8)

Case studies in the past repeatedly suggested that the fundamental alteration in Crohn's disease occurs in the regional lymphatics of the intestine.To evaluate the lymphatic inflammation in Crohn's disease, and to characterise lymphoid aggregates and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5838e522aa723a19f6e481271a907942
https://pubmed.ncbi.nlm.nih.gov/21366631

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