Zobrazeno 1 - 10
of 60
pro vyhledávání: '"R. Stewart Gilmour"'
Autor:
Murray D. Mitchell, Timothy A. Sato, Elicia B.E Berry, Rachel J. A. Helliwell, R. Stewart Gilmour
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 71:191-197
Cyclopentenone prostaglandins, Delta(12)-PGJ(2) and 15d-PGJ(2), have potent anti-tumour and anti-inflammatory activities, and have been shown to induce apoptosis in amnion-derived WISH cells. In this study, we have investigated the protective effects
Autor:
R. Stewart Gilmour, K.W. Marvin, Elicia B.E Berry, R.L. Eykholt, Murray D. Mitchell, Rachel J. A. Helliwell
Publikováno v:
Molecular Pharmacology. 64:1586-1590
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that are involved in lipid metabolism, differentiation, proliferation, cell death, and inflammation. Three subtypes have been identified: PPAR-alpha, -delta, and -g
Publikováno v:
Advances in Enzyme Regulation. 43:1-13
Autor:
Irene Faenza, Pann-Ghill Suh, Alberto M. Martelli, R. Stewart Gilmour, Lucio Cocco, Alberto Bavelloni, Sandra Marmiroli, Alessandro Matteucci, Lucia Manzoli
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1589:305-310
It is well established that phospholipase C (PLC) h1 plays a role in the nuclear compartment and is involved in the signalling pathway that controls the switching of the erythroleukemia cells programming from an undifferentiated to a differentiated s
Autor:
Francesco A. Manzoli, R. Stewart Gilmour, O. Barnabei, Lucio Cocco, Mirella Falconi, Alberto M. Martelli, Marco Vitale
Publikováno v:
Advances in Enzyme Regulation. 42:181-193
Autor:
Elicia B. E. Berry, K.W. Marvin, R. Stewart Gilmour, Bianca E. Nijmeijer, Jeffrey A. Keelan, Murray D. Mitchell, Rachel J. A. Helliwell, Timothy A. Sato
Publikováno v:
Prostaglandins & Other Lipid Mediators. 66:265-282
Apoptosis at the site of rupture has been proposed to play a role in premature rupture of the fetal membranes, a condition associated with increased risk of neonatal sepsis and preterm birth. We investigated the ability of peroxisome proliferator-act
Publikováno v:
Journal of Biological Chemistry. 276:14980-14986
Previous studies from several independent laboratories have demonstrated the existence of an autonomous phosphoinositide (PI) cycle within the nucleus, where it is involved in both cell proliferation and differentiation. Stimulation of Swiss 3T3 cell
Autor:
Irene Faenza, Lucio Cocco, Anto De Pol, Michela Aluigi, Lucia Manzoli, Alberto M. Martelli, Anna Maria Billi, Mirella Falconi, R. Stewart Gilmour
Publikováno v:
FEBS Letters. 486:230-236
Using NIH 3T3 cells, we have investigated nuclear phosphoinositide metabolism in response to insulin, a molecule which acts as a proliferating factor for this cell line and which is known as a powerful activator of the mitogen-activated protein (MAP)
Autor:
Daniela Peruzzi, Irene Faenza, Lucia Manzoli, R. Stewart Gilmour, Sue Goo Rhee, Marco Artico, Alessandro Matteucci, Silvia Rubbini, Anna Maria Billi, Lucio Cocco
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1438:295-299
Previous reports from our laboratories and others have hinted that the nucleus is a site for an autonomous signalling system acting through the activation of the inositol lipid cycle. Among phospholipases (PLC) it has been shown previously that PLCbe
Autor:
R. Stewart Gilmour, Riccardo Rizzoli, Nadir M. Maraldi, Silvano Capitani, Karel W. A. Wirtz, Lucio Cocco, Francesco A. Manzoli, O. Barnabei, Giovanni Mazzotti, S G Rhee
Publikováno v:
Advances in Enzyme Regulation. 38:351-363
The nucleus was shown to be a site for inositol lipid cycle which can be affected by treatment of quiescent cells with growth factors such as IGF-I. In fact, the exposure of Swiss 3T3 cells to IGF-I results in a rapid and transient increase in nuclea