First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction

Autor: Rohan Ameratunga, See-Tarn Woon, Mary N. Sheppard, Jack Garland, Benjamin Ondruschka, Christopher X. Wong, Ralph A. H. Stewart, Michael Tatley, Simon R. Stables, Rexson D. Tse

Publikováno v: Journal of Clinical Immunology

Rationale Transient myopericarditis has been recognised as an uncommon and usually mild adverse event predominantly linked to mRNA-based COVID-19 vaccines. These have mostly occurred in young males after the second dose of mRNA COVID-19 vaccines. Obj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f9ad1b339f122fbaedcbbed9f756fb
http://europepmc.org/articles/PMC8720536

A pilot randomised controlled trial in intensive care patients comparing 7 days’ treatment with empirical antibiotics with 2 days’ treatment for hospital-acquired infection of unknown origin

Autor: N Scawn, D Saul, D Pathak, B Matata, I Kemp, R Stables, S Lane, A Haycox, R Houten

Publikováno v: Health Technology Assessment, Vol 16, Iss 36 (2012)

Background: Management of cardiac intensive care unit (ICU) sepsis is complicated by the high incidence of systemic inflammatory response syndrome, which mimics sepsis but without an infective cause. This pilot randomised trial investigated whether o

Externí odkaz: https://doaj.org/article/2915ecf15e11453ea1fbef16ed4546d0

Safety of Perioperative Aprotinin Administration During Isolated Coronary Artery Bypass Graft Surgery: Insights From the ART (Arterial Revascularization Trial)

Autor: Umberto Benedetto, Douglas G. Altman, Stephen Gerry, Alastair Gray, Belinda Lees, Gianni D. Angelini, Marcus Flather, David P. Taggart, C. Ratnatunga, S. Westaby, J. Cook, C. Wallis, S. Wos, M. Jasinski, K. Widenka, A. Blach, R. Gocol, D. Hudziak, P. Zurek, M. Deja, R. Bachowski, R. Mrozek, T. Kargul, W. Domarardzki, J. Frackiewicz, V. Zamvar, D. Ezakadan, B. Buxton, S. Seevanayagam, G. Matalanis, A. Rosalion, J. Negri, S. Moten, V. Atkinson, A. Newcomb, P. Polidano, R. Pana, S. Gerbo, P. O'Keefe, U. von Oppell, D. Mehta, A. Azzu, A. Szafranek, E. Kulatilake, J. Evans, N. Martin, D. Banner, U. Trivedi, A. Forsyth, J. Hyde, A. Cohen, M. Lewis, E. Gardner, A. MacKenzie, N. Cooter, E. Joyce, J. Parker, F. Champney, S. Clark, J. Dark, K. Tocewicz, T. Pillay, S. Rowling, J. Adams‐Hall, A. Bochenek, M. Cisowski, M. Bolkowski, W. Morawski, M. Guc, M. Krejca, M. Wilczynski, A. Duralek, W. Gerber, J. Skarysz, R. Shrestha, W. Swiech, P. Szmagala, L. Krzych, A. Pawlak, K. Kepa, R. Hasan, D. Keenan, B. Prendergast, N. Odom, K. McLaughlin, G. Cummings‐Fosong, C. Mathew, H. Iles‐Smith, A. Oomen, J. Desai, A. El‐Gamel, L. John, O. Wendler, M. Andrews, K. Rance, R. Williams, V. Hogervorst, J. Gregory, J. Jessup, A. Knighton, A. Hoare, A. Ritchie, C. Choong, S. Nair, D. Jenkins, S. Large, C. Sudarshan, M. Barman, K. Dhital, T. Routledge, B. Rosengard, H. Munday, K. Rintoul, E. Jarrett, S. Lao‐Sirieix, A. Wilkinson, L. Garner, J. Osmond, H. Holcombe, A. Cale, S. Griffin, J. Dickson, T. Spyt, M. Hickey, A. Sosnowski, G. Peek, J. Szostek, L. Hadjinikalaou, E. Logtens, M. Oakley, S. Leji, J. Gaer, M. Amrani, G. Dreyfus, T. Bahrami, F. de Robertis, K. Baig, G. Asimakopoulos, H. Vohra, V. Pai, S. Tadjkarimi, B. Soleimani, G. Stavri, G. Bull, H. Collappen, J. Sadowksi, B. Gaweda, P. Rudzinski, J. Stolinski, J. Konstanty‐Kalandyk, F. Moraes, C. Moraes, J. Wanderley, J. Pepper, A. De Souza, M. Petrou, R. Trimlett, T. Morgan, J. Gavino, S.F. Wang, V. Chandrasekaran, R. Kanagasaby, M. Sarsam, H. Ryan, L. Billings, L. Ruddick, A. Achampong, E. Forster, R. Pawlaczyk, P. Siondalski, J. Rogowski, K. Roszak, K. Jarmoszewicz, D. Jagielak, S. Gafka, G. Mannam, G. Naguboyin, L. Rao Sajja, B. Dandu, N. Briffa, P. Braidley, G. Cooper, K. Allen, G. Sangha, C. Bridge, H. McMellon, R. Casabona, G. Actis Dato, G. Bardi, S. Del Ponte, P. Forsennati, F. Parisi, G. Punta, R. Flocco, F. Sansone, E. Zingarelli, W. Dihmis, M. Kuduvali, C. Prince, H. Rogers, L. McQuade, L. Anisimowicz, M. Bokszanski, W. Pawliszak, J. Kolakowski, G. Lau, W. Ogorzeja, I. Gumanska, P. Kulinski, B. Podesser, K. Trescher, O. Bernecker, C. Holzinger, K. Binder, I. Schor, P. Bergmann, H. Kassal, B. Motovova, N. Trehan, Z. Meharwal, R. Malhotra, M. Goel, B. Kumer, S. Bazaz, N. Bake, A. Singh, Y. Mishka, R. Gupta, S. Basumatary, M. Zembala, B. Szafron, J. Pacholewicz, M. Krason, A. Farmas, J. Wojarski, B. Zych, I. Szymanik, M. Kolwca, W. Mazur, A. Kurowicki, S. Zurek, T. Stacel, I. Jaworska, P. Sleight, K. Channon, B. Farrell, R. Stables, G. Vermes, J. Pearson, M. Pitman, S. Yusuf, S. Pocock, D. Julian, T. Treasure, U. Von Oppel, R. Kanagasabay, J. Collinson, A. Bakhai, R. O'Hanlon, D. Kotecha, K. Qureshi, T. Geisler, L. Manzano‐Espinosa

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Benedetto, U, Altman, D G, Gerry, S, Gray, A, Lees, B, Angelini, G D, Flather, M, Taggart, D P 2018, ' Safety of Perioperative Aprotinin Administration During Isolated Coronary Artery Bypass Graft Surgery: Insights From the ART (Arterial Revascularization Trial) ', Journal of the American Heart Association, vol. 7, no. 5, e007570 . https://doi.org/10.1161/JAHA.117.007570

BackgroundThere is still uncertainty about the safety of aprotinin for coronary artery bypass graft surgery. The ART (Arterial Revascularization Trial) was designed to compare survival after bilateral versus single internal thoracic artery grafting.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5a30645f66da8a35d6bc0c0a4ab0d3

Gastric anti-secretory, mucosal protective, anti-pepsin and anti-Helicobacter properties of ranitidine bismuth citrate

Autor: J. W. Clitherow, R. Stables, N. M. Clayton, C. J. Grinham, A. McLAREN, A. A. McCOLM, C. J. Campbell, M. A. Trevethick

Publikováno v: Alimentary Pharmacology & Therapeutics. 7:237-246

SUMMARY Ranitidine bismuth citrate is a novel compound formed from ranitidine and a bismuth citrate complex. In conscious dogs, ranitidine bismuth citrate had similar activity to ranitidine hydrochloride as an inhibitor of histamine-induced gastric a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1af5c91d8eac516686e44276401ecc
https://doi.org/10.1111/j.1365-2036.1993.tb00094.x

Involvement of an enchondroma in relapsing polychondritis

Autor: P J, Poole, D E, Caughey, J, Kolbe, C J, Mercer, S R, Stables

Publikováno v: The Journal of rheumatology. 23(1)

We describe a 49-year-old Caucasian woman with relapsing polychondritis involving ears, eyes, nose, and airways. An enchondroma in the left humerus was also involved. This unusual manifestation of the disease has not been previously reported.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a26ddecfcfca4e8c6799289ac1ef8dea
https://pubmed.ncbi.nlm.nih.gov/8838532