Zobrazeno 1 - 10
of 150
pro vyhledávání: '"R. Srivatsan"'
As Reinforcement Learning (RL) agents are increasingly employed in diverse decision-making problems using reward preferences, it becomes important to ensure that policies learned by these frameworks in mapping observations to a probability distributi
Externí odkaz:
http://arxiv.org/abs/2307.13192
Autor:
David F. Read, Gregory T. Booth, Riza M. Daza, Dana L. Jackson, Rula Green Gladden, Sanjay R. Srivatsan, Brent Ewing, Jennifer M. Franks, Cailyn H. Spurrell, Anne Roshella Gomes, Diana O’Day, Aishwarya A. Gogate, Beth K. Martin, Haleigh Larson, Christian Pfleger, Lea Starita, Yiing Lin, Jay Shendure, Shin Lin, Cole Trapnell
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Sex differences and age-related changes in the human heart at the tissue, cell, and molecular level have been well-documented and many may be relevant for cardiovascular disease. However, how molecular programs within individual cell types v
Externí odkaz:
https://doaj.org/article/c78d59de759c46328c8bc8b520ab680e
Autor:
Gregory T. Booth, Riza M. Daza, Sanjay R. Srivatsan, José L. McFaline-Figueroa, Rula Green Gladden, Andrew C. Mullen, Scott N. Furlan, Jay Shendure, Cole Trapnell
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-23 (2023)
Abstract Single-cell chromatin accessibility has emerged as a powerful means of understanding the epigenetic landscape of diverse tissues and cell types, but profiling cells from many independent specimens is challenging and costly. Here we describe
Externí odkaz:
https://doaj.org/article/11167b29a9ec4b1fa5f656373a3275ff
Autor:
Mohammad Lotfollahi, Anna Klimovskaia Susmelj, Carlo De Donno, Leon Hetzel, Yuge Ji, Ignacio L Ibarra, Sanjay R Srivatsan, Mohsen Naghipourfar, Riza M Daza, Beth Martin, Jay Shendure, Jose L McFaline‐Figueroa, Pierre Boyeau, F Alexander Wolf, Nafissa Yakubova, Stephan Günnemann, Cole Trapnell, David Lopez‐Paz, Fabian J Theis
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 6, Pp 1-19 (2023)
Abstract Recent advances in multiplexed single‐cell transcriptomics experiments facilitate the high‐throughput study of drug and genetic perturbations. However, an exhaustive exploration of the combinatorial perturbation space is experimentally u
Externí odkaz:
https://doaj.org/article/418ea36376f0413cb228551ff196f2db
Autor:
Tessa Dignum, Barbara Varnum-Finney, Sanjay R. Srivatsan, Stacey Dozono, Olivia Waltner, Adam M. Heck, Takashi Ishida, Cynthia Nourigat-McKay, Dana L. Jackson, Shahin Rafii, Cole Trapnell, Irwin D. Bernstein, Brandon Hadland
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109675- (2021)
Summary: During embryogenesis, waves of hematopoietic progenitors develop from hemogenic endothelium (HE) prior to the emergence of self-renewing hematopoietic stem cells (HSCs). Although previous studies have shown that yolk-sac-derived erythromyelo
Externí odkaz:
https://doaj.org/article/aeadf5874656435cb00af40d81bd981a
Autor:
Mitra, Sanga, BP, Kailash, C R, Srivatsan, Saikumar, Naga Venkata, Philip, Philge, Narayanan, Manikandan
Publikováno v:
NPJ Systems Biology & Applications; 5/9/2024, Vol. 10 Issue 1, p1-16, 16p
Autor:
R Srivatsan
Publikováno v:
Indian Journal of Medical Ethics. 8:157-159
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c256e313adf3ec2c8a07e611e6121b1
https://doi.org/10.20529/ijme.2022.063
https://doi.org/10.20529/ijme.2022.063
Autor:
Andrew J. Aman, Lauren M. Saunders, August A. Carr, Sanjay R. Srivatsan, Colten D. Eberhard, Blake Carrington, Dawn Watkins-Chow, William J. Pavan, Cole Trapnell, David M. Parichy
Pigment patterns and skin appendages are prominent features of vertebrate skin. In zebrafish, regularly patterned pigment stripes and an array of calcified scales form simultaneously in the skin during post-embryonic development. Understanding mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd61bc242e9a8cb09d17d95b2b8d884a
https://doi.org/10.7554/elife.86670.1
https://doi.org/10.7554/elife.86670.1
Autor:
Natasha I Edman, Rachel L Redler, Ashish Phal, Thomas Schlichthaerle, Sanjay R Srivatsan, Ali Etemadi, Seong An, Andrew Favor, Devon Ehnes, Zhe Li, Florian Praetorius, Max Gordon, Wei Yang, Brian Coventry, Derrick R Hicks, Longxing Cao, Neville Bethel, Piper Heine, Analisa N Murray, Stacey Gerben, Lauren Carter, Marcos Miranda, Babak Negahdari, Sangwon Lee, Cole Trapnell, Lance Stewart, Damian C Ekiert, Joseph Schlessinger, Jay Shendure, Gira Bhabha, Hannele Ruohola-Baker, David Baker
Publikováno v:
bioRxiv
Growth factors and cytokines signal by binding to the extracellular domains of their receptors and drive association and transphosphorylation of the receptor intracellular tyrosine kinase domains, initiating downstream signaling cascades. To enable s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabf19b52c9e40ae334b69d4789b7567
https://europepmc.org/articles/PMC10055045/
https://europepmc.org/articles/PMC10055045/
Autor:
R Srivatsan
Publikováno v:
Indian Journal of Medical Ethics. 8:66-67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa28400b9013ef8162dd3716b4017e6a
https://doi.org/10.20529/ijme.2023.005
https://doi.org/10.20529/ijme.2023.005