Zobrazeno 1 - 10
of 271
pro vyhledávání: '"R. Spicer"'
Autor:
Claudia Tulotta, Diane V. Lefley, Charlotte K. Moore, Ana E. Amariutei, Amy R. Spicer-Hadlington, Lewis A. Quayle, Russell O. Hughes, Khawla Ahmed, Victoria Cookson, Catherine A. Evans, Jayakumar Vadakekolathu, Paul Heath, Sheila Francis, Emmanuel Pinteaux, A. Graham Pockley, Penelope D. Ottewell
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Breast cancer bone metastasis is currently incurable, ~75% of patients with late-stage breast cancer develop disease recurrence in bone and available treatments are only palliative. We have previously shown that production of the pro-inflamm
Externí odkaz:
https://doaj.org/article/db7c85c82ea947e69d237a3402f52c96
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Summary of the effects of IL-1B on breast cancer progression to metastasis and growth in the bone microenvironment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c966886aa3515add73124f35ba96fdd4
https://doi.org/10.1158/1078-0432.22472744.v1
https://doi.org/10.1158/1078-0432.22472744.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Suppression of IL-1 signalling affects bone integrity and vasculature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c325261461851db8ab242f40b164f0c7
https://doi.org/10.1158/1078-0432.22472750.v1
https://doi.org/10.1158/1078-0432.22472750.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44d71f01e6bbe78530a36fc9eede0dc
https://doi.org/10.1158/1078-0432.22472741.v1
https://doi.org/10.1158/1078-0432.22472741.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Effects of IL-1B on osteoclast and osteoblast activity in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b007b54acb30669ee466909235f57
https://doi.org/10.1158/1078-0432.22472747.v1
https://doi.org/10.1158/1078-0432.22472747.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Incubation with high concentrations of exogenous IL-1B modestly increases tumour cell migration and invasion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ba561472369534842ef8e89064113d
https://doi.org/10.1158/1078-0432.22472756.v1
https://doi.org/10.1158/1078-0432.22472756.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
In vivo model of spontaneous human breast cancer metastasis to human bone implants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6e4ee90c1febd67029eac311f790e5
https://doi.org/10.1158/1078-0432.22472765.v1
https://doi.org/10.1158/1078-0432.22472765.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Purpose:Breast cancer bone metastases are incurable, highlighting the need for new therapeutic targets. After colonizing bone, breast cancer cells remain dormant, until signals from the microenvironment stimulate outgrowth into overt metastases. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1129d3ad9037fd9bc83853742bf10c0d
https://doi.org/10.1158/1078-0432.c.6528317.v1
https://doi.org/10.1158/1078-0432.c.6528317.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Tumour-derived IL-1B predicts distant recurrence and relapse in bone in patients with stage II and III breast cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e0a76acf3cefda65018e93855c5112
https://doi.org/10.1158/1078-0432.22472738.v1
https://doi.org/10.1158/1078-0432.22472738.v1
Autor:
Penelope D. Ottewell, Ingunn Holen, Janet E. Brown, Robert E. Coleman, Marianna Kruithof de Julio, Gloria Allocca, Victoria Cookson, Lisa Hambley, Steven M.J. Bradbury, Xinming Liu, Amy R. Spicer-Hadlington, J. Mark Wilkinson, Faith Nutter, Paul R. Heath, Andrew M. Hanby, Walter M. Gregory, Katy Freeman, Diane V. Lefley, Claudia Tulotta
Stable transfection of breast cancer cells with IL-1B.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad6ed608603a8b661930e3a0479061b
https://doi.org/10.1158/1078-0432.22472759.v1
https://doi.org/10.1158/1078-0432.22472759.v1