Zobrazeno 1 - 10
of 235
pro vyhledávání: '"R. Spaulding"'
Autor:
Swathy Krishna, Hannah R. Spaulding, James E. Koltes, John C. Quindry, Rudy J. Valentine, Joshua T. Selsby
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Duchenne muscular dystrophy (DMD) is a progressive muscle disease that results in muscle wasting, wheelchair dependence, and eventual death due to cardiac and respiratory complications. In addition to muscle fragility, dystrophin deficiency also resu
Externí odkaz:
https://doaj.org/article/e24a80efa87547af8ced1ecc2e6fb343
Autor:
Ciara N. Manning, Yasuki Sekiguchi, Courteney L. Benjamin, McKenna R. Spaulding, Erin E. Dierickx, Jayson M. Spaulding, Dayshia M. Davenport, Jillian R. Picard-Busky, George T. Chiampas, George P. Nassis, Douglas J. Casa
Publikováno v:
Frontiers in Sports and Active Living, Vol 4 (2022)
Recruiting companies recommend elite female soccer players be ≥165 cm (5′5″) in stature. This study investigated if stature limits match-playing time and performance in elite World Cup soccer among players, positions, and countries. We hypothes
Externí odkaz:
https://doaj.org/article/66fa2a7c921245739af05cfd9acc4ccb
Indices of Defective Autophagy in Whole Muscle and Lysosome Enriched Fractions From Aged D2-mdx Mice
Autor:
Swathy Krishna, Hannah R. Spaulding, Tiffany S. Quindry, Matthew B. Hudson, John C. Quindry, Joshua T. Selsby
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Duchenne muscular dystrophy (DMD) is a fatal, progressive muscle disease caused by the absence of functional dystrophin protein. Previous studies in mdx mice, a common DMD model, identified impaired autophagy with lysosomal insufficiency and impaired
Externí odkaz:
https://doaj.org/article/8dbd602249e14a72b3e5807d72283ba8
Autor:
Zhen Yan, Hannah R. Spaulding
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Extracellular superoxide dismutase (EcSOD) is the only extracellular scavenger of superoxide anion (O2.-) with unique binding capacity to cell surface and extracellular matrix through its heparin-binding domain. Enhanced EcSOD activity prevents oxida
Externí odkaz:
https://doaj.org/article/e40d9db3f3684c2a85ecd15eb88cd4fe
Publikováno v:
Physiological Reports, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Duchenne muscular dystrophy (DMD) is caused by the absence of functional dystrophin protein and results in progressive muscle wasting. Dystrophin deficiency leads to a host of dysfunctional cellular processes including impaired autophagy. Au
Externí odkaz:
https://doaj.org/article/cd26f90403c1472abea8ab55f08d7629
Autor:
Hannah R. Spaulding, Zhen Yan
Publikováno v:
Annu Rev Physiol
Noncommunicable diseases are chronic diseases that contribute to death worldwide, but these diseases can be prevented and mitigated with regular exercise. Exercise activates signaling molecules and the transcriptional network to promote physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef8c66528bbd4fb15e6015a33a8cbe8
https://doi.org/10.1146/annurev-physiol-060721-095517
https://doi.org/10.1146/annurev-physiol-060721-095517
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168293 (2016)
Duchenne muscular dystrophy (DMD) results from a genetic lesion in the dystrophin gene and leads to progressive muscle damage. PGC-1α pathway activation improves muscle function and decreases histopathological injury. We hypothesized that mild disea
Externí odkaz:
https://doaj.org/article/2d6cf1e43fda462fb88b52597126cc17
Autor:
Ruofan Cao, David F. Kashatus, Eric M. Desjardins, Anna S. Nichenko, Jitendra Gautam, Matthew H. Brisendine, Huayu Shang, Hannah R. Spaulding, D. Grahame Hardie, Joshua C. Drake, Yuntian Guan, Horst Wallrabe, Mei Zhang, Maya V. Dorn, Aloka B. Bandara, Rebecca J. Wilson, Matthew J. Wolf, Michael Wong, Jennifer A. Kashatus, Gregory R. Steinberg, Kian Huang, Clint L. Miller, Simon A. Hawley, George J. Christ, Wenqing Shen, Poonam Sharma, Paul A. Chang, Zhen Yan, Ammasi Periasamy, Alexander S. Young, Rhianna C. Laker
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Here, we present unequivocal evidence of physical association of AMPK holoenzymes with mitochondrial reticulum (mitoAMPK) across multiple mouse tissues with evidence of conservation in human skeletal muscle and heart. We demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacd6cacaed2ee2763e46a56be4eb882
https://hdl.handle.net/10919/107452
https://hdl.handle.net/10919/107452
Indices of Defective Autophagy in Whole Muscle and Lysosome Enriched Fractions From Aged D2-mdx Mice
Autor:
Matthew B. Hudson, Swathy Krishna, Hannah R. Spaulding, Joshua T. Selsby, John C. Quindry, Tiffany S. Quindry
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Duchenne muscular dystrophy (DMD) is a fatal, progressive muscle disease caused by the absence of functional dystrophin protein. Previous studies in mdx mice, a common DMD model, identified impaired autophagy with lysosomal insufficiency and impaired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be22507acb836ce0b025870c22b489c6
http://europepmc.org/articles/PMC8299564
http://europepmc.org/articles/PMC8299564
Publikováno v:
J Appl Physiol (1985)
Progressive muscle injury and weakness are hallmarks of Duchenne muscular dystrophy. We showed previously that quercetin (Q) partially protected dystrophic limb muscles from disease-related injury. As quercetin activates PGC-1α through Sirtuin-1, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440b473f77f50dfe0ac6217558644f8f
https://doi.org/10.1152/japplphysiol.00162.2019
https://doi.org/10.1152/japplphysiol.00162.2019