Zobrazeno 1 - 10
of 27
pro vyhledávání: '"R. Soskind"'
Publikováno v:
Drug Discov Today
Open access to 3D structure information from the Protein Data Bank (PDB) facilitated discovery and development of >90% of the 79 new antineoplastic agents (54 small molecules, 25 biologics) with known molecular targets approved by the FDA 2010–2018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342f040837f32fe427ce20ac798f38ba
https://doi.org/10.1016/j.drudis.2020.02.002
https://doi.org/10.1016/j.drudis.2020.02.002
Publikováno v:
Journal of Bioactive and Compatible Polymers. 32:3-16
In this work, pH-sensitive amphiphilic macromolecules are designed to possess good biocompatibility and drug loading while employing an acid-sensitive linkage to trigger drug release at tumor tissues. Specifically, two pH-sensitive amphiphilic macrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1819ab0848b7e1198904d414e00939e7
https://doi.org/10.1177/0883911516643219
https://doi.org/10.1177/0883911516643219
Publikováno v:
Expert opinion on pharmacotherapy. 18(11)
Gout is a rheumatologic condition associated with elevated serum uric acid levels and deposition of monosodium urate crystals in joints and soft tissues. Areas covered: In this article, we describe the role of currently available drug therapies for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c56609b859aa71883265ee4071eec29
https://pubmed.ncbi.nlm.nih.gov/28658988
https://pubmed.ncbi.nlm.nih.gov/28658988
Publikováno v:
SPIE Proceedings.
Due to their several unique properties, propagation invariant laser beams (PILBs) are playing an increasingly important role in several photonics applications. This paper describes some practical aspects of producing propagation invariant laser beams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9674819f1f4c3dc8df6bc97530c7c4de
https://doi.org/10.1117/12.2188347
https://doi.org/10.1117/12.2188347
Publikováno v:
SPIE Proceedings.
We describe a novel coherent radiation enhancement technique and its application to laser beam shaping. The technique is based on coherent transformations of the propagating radiation employing amplitude and/or phase structures, and produces localize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb8f073e3a78b0bb3b46953d6ddc8b10
https://doi.org/10.1117/12.2063031
https://doi.org/10.1117/12.2063031
Publikováno v:
SPIE Proceedings.
Bessel beams belong to a class of propagation invariant, structured laser beams, and are used in various applications, including particle micro-manipulation, optical coherence tomography, optical metrology, and high resolution microscopy. In practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b8870fd4dd62bc734ad3412c8795cdd
https://doi.org/10.1117/12.2023769
https://doi.org/10.1117/12.2023769
Publikováno v:
SPIE Proceedings.
The coherent superposition of propagation-invariant laser beams represents an important beam-shaping technique, and results in new beam shapes which retain the unique property of propagation invariance. Propagation-invariant laser beam shapes depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0ea12f0138561a588254a3d1a1b22d
https://doi.org/10.1117/12.932233
https://doi.org/10.1117/12.932233
Publikováno v:
SPIE Proceedings.
We propose a novel super-resolution scanning microscopy technique employing higher-order propagationinvariant laser beams. The technique is capable of resolving objects with lateral dimensions smaller than that of the focal spot size defined by a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0edef88147ae513d96dcd64a24050ba8
https://doi.org/10.1117/12.929163
https://doi.org/10.1117/12.929163
Autor:
R. Soskind, Y. G. Soskind
Publikováno v:
SPIE Proceedings.
In this paper, we present a novel technique for beam shaping and mode conversion of elliptical laser beams employing vortex phase elements. We show that a vortex phase element with topological charge m=1 can effectively switch between elliptically sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ede5fcfef140092397b5d94f4b08fa9
https://doi.org/10.1117/12.890505
https://doi.org/10.1117/12.890505
Publikováno v:
SPIE Proceedings.
In this paper we will be discussing different techniques fo r producing superresolved point- spread functions (PSFs) that are based on amplitude and phase pupil masks. We propose a novel method of producing elongated superresolved point-spread functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4993654c013281a3e6f6a5a2d8ccfefa
https://doi.org/10.1117/12.859963
https://doi.org/10.1117/12.859963