Zobrazeno 1 - 10
of 264
pro vyhledávání: '"R. Soeters"'
Autor:
S. Majait, F. M. Vaz, E. Marleen Kemper, A. H. Bootsma, A. K. Groen, M. Nieuwdorp, Maarten R. Soeters
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Background3β-hydroxy-Δ5-C27-steroid-oxidoreductase (3β-HSD) deficiency is a bile acid synthesis disorder that leads to the absence of normal primary bile acids and the accumulation of abnormal bile acids. This results in cholestatic jaundice, fat-
Externí odkaz:
https://doaj.org/article/a6b5fb9bc72348e7aacdf1fdb40e243e
Autor:
Moritz V. Warmbrunn, Harsh Bahrar, Nicolien C. de Clercq, Annefleur M. Koopen, Pieter F. de Groot, Joost Rutten, Leo A. B. Joosten, Ruud S. Kootte, Kristien E. C. Bouter, Kasper W. ter Horst, Annick V. Hartstra, Mireille J. Serlie, Maarten R. Soeters, Daniel H. van Raalte, Mark Davids, Evgeni Levin, Hilde Herrema, Niels P. Riksen, Mihai G. Netea, Albert K. Groen, Max Nieuwdorp
Publikováno v:
Nutrients, Vol 16, Iss 12, p 1822 (2024)
Context/Objective: In order to better understand which metabolic differences are related to insulin resistance in metabolic syndrome (MetSyn), we used hyperinsulinemic–euglycemic (HE) clamps in individuals with MetSyn and related peripheral insulin
Externí odkaz:
https://doaj.org/article/c9a5b2be04634c13a2be6bcf5a19df26
Autor:
Soumia Majait, Emma C. E. Meessen, Mark Davids, Youssef Chahid, Steven W. Olde Damink, Frank G. Schaap, Ellis Marleen Kemper, Max Nieuwdorp, Maarten R. Soeters
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 764 (2024)
Ageing changes the impact of nutrition, whereby inflammation has been suggested to play a role in age-related disabilities such as diabetes and cardiovascular disease. The aim of this study was to investigate differences in postprandial bile-acid res
Externí odkaz:
https://doaj.org/article/c3ae8cb37f4346f9aaae2b749679b0c6
Autor:
Aline C. Fenneman, Anne H. van der Spek, Annick Hartstra, Stefan Havik, Anne Salonen, Willem M. de Vos, Maarten R. Soeters, Peeroz Saeed, Max Nieuwdorp, Elena Rampanelli
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundGraves’ disease (GD) and Graves’ orbitopathy (GO) result from ongoing stimulation of the TSH receptor due to autoantibodies acting as persistent agonists. Orbital pre-adipocytes and fibroblasts also express the TSH receptor, resulting i
Externí odkaz:
https://doaj.org/article/0c12ab6d96ab469ca51e8b85f865913c
Autor:
Marlinde L. van Dijk, Leonie M. te Loo, Joyce Vrijsen, Inge van den Akker-Scheek, Sanne Westerveld, Marjan Annema, André van Beek, Jip van den Berg, Alexander L. Boerboom, Adrie Bouma, Martine de Bruijne, Jeroen Crasborn, Johanna M. van Dongen, Anouk Driessen, Karin Eijkelenkamp, Nies Goelema, Jasmijn Holla, Johan de Jong, Anoek de Joode, Arthur Kievit, Josine van’t Klooster, Hinke Kruizenga, Marike van der Leeden, Lilian Linders, Jenny Marks-Vieveen, Douwe Johannes Mulder, Femmy Muller, Femke van Nassau, Joske Nauta, Suzanne Oostvogels, Jessica Oude Sogtoen, Hidde P. van der Ploeg, Patrick Rijnbeek, Linda Schouten, Rhoda Schuling, Erik H. Serné, Simone Smuling, Maarten R. Soeters, Evert A. L. M. Verhagen, Johannes Zwerver, Rienk Dekker, Willem van Mechelen, Judith G. M. Jelsma
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background A healthy lifestyle is indispensable for the prevention of noncommunicable diseases. However, lifestyle medicine is hampered by time constraints and competing priorities of treating physicians. A dedicated lifestyle front office (
Externí odkaz:
https://doaj.org/article/b59b2025dcfb4fe5a2cab6059ca5005b
Autor:
Soumia Majait, Emma C. E. Meessen, Frederic Maxime Vaz, E. Marleen Kemper, Samuel van Nierop, Steven W. Olde Damink, Frank G. Schaap, Johannes A. Romijn, Max Nieuwdorp, Aad Verrips, Filip Krag Knop, Maarten R. Soeters
Publikováno v:
Nutrients, Vol 15, Iss 21, p 4625 (2023)
Cerebrotendinous xanthomatosis (CTX) is a rare inherited disease characterized by sterol 27-hydroxylase (CYP27A1) deficiency and, thus, a lack of bile acid synthesis with a marked accumulation of 7α-hydroxylated bile acid precursors. In addition to
Externí odkaz:
https://doaj.org/article/30a1913f292d42df954fa2300b9ef17c
Autor:
Suzanne Meiring, Annieke C. G. van Baar, Nikolaj Sørensen, Frits Holleman, Maarten R. Soeters, Max Nieuwdorp, Jacques J. G. H. M. Bergman
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 3 (2022)
IntroductionThe gut microbiota influences and interacts with the host metabolism through effects on nutrient metabolism and digestion. Duodenal Mucosal Resurfacing (DMR) is a novel endoscopic procedure involving duodenal mucosal ablation by the use o
Externí odkaz:
https://doaj.org/article/6ce26dc770ea4b7bb65a5be18797c0b3
Autor:
Annick V. Hartstra, Pieter F. deGroot, Diogo Mendes Bastos, Evgeni Levin, Mireille J. Serlie, Maarten R. Soeters, Ceyda T. Pekmez, Lars O. Dragsted, Mariette T. Ackermans, Albert K. Groen, Max Nieuwdorp
Publikováno v:
Obesity Science & Practice, Vol 6, Iss 3, Pp 340-349 (2020)
Summary Objective Insulin resistance develops prior to the onset of overt type 2 diabetes, making its early detection vital. Direct accurate evaluation is currently only possible with complex examinations like the stable isotope‐based hyperinsuline
Externí odkaz:
https://doaj.org/article/ca10f7dadf494d05b97a0ed7f1791360
Autor:
Emma C. E. Meessen, Håvard Andresen, Thomas van Barneveld, Anne van Riel, Egil I. Johansen, Anders J. Kolnes, E. Marleen Kemper, Steven W. M. Olde Damink, Frank G. Schaap, Johannes A. Romijn, Jørgen Jensen, Maarten R. Soeters
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Background: Generally, food intake occurs in a three-meal per 24 h fashion with in-between meal snacking. As such, most humans spend more than ∼ 12–16 h per day in the postprandial state. It may be reasoned from an evolutionary point of view, tha
Externí odkaz:
https://doaj.org/article/51392d8ace4b407dbde8e9be9c4d5c8a
Autor:
Marjoleine F. Broekema, Maarten P.G. Massink, Cinzia Donato, Joep de Ligt, Joerg Schaarschmidt, Anouska Borgman, Marieke G. Schooneman, Diana Melchers, Martin N. Gerding, René Houtman, Alexandre M.J.J. Bonvin, Amit R. Majithia, Houshang Monajemi, Gijs W. van Haaften, Maarten R. Soeters, Eric Kalkhoven
Publikováno v:
Molecular Metabolism, Vol 20, Iss , Pp 115-127 (2019)
Objective: The nuclear receptor PPARγ is the master regulator of adipocyte differentiation, distribution, and function. In addition, PPARγ induces terminal differentiation of several epithelial cell lineages, including colon epithelia. Loss-of-func
Externí odkaz:
https://doaj.org/article/53f1ce77e920425c99f8b77ad47374db