Zobrazeno 1 - 10
of 25
pro vyhledávání: '"R. Smithwick"'
Autor:
R. Hunter Wilson, Sourav Chatterjee, Elizabeth R. Smithwick, Joseph J. Dalluge, Ambika Bhagi-Damodaran
Publikováno v:
ACS Catalysis. 12:10913-10924
Autor:
Elizabeth R. Smithwick, R. Hunter Wilson, Sourav Chatterjee, Yu Pu, Joseph J. Dalluge, Anoop Rama Damodaran, Ambika Bhagi-Damodaran
Publikováno v:
bioRxiv
Non-heme iron halogenases (NHFe-Hals) catalyze the direct insertion of a chloride/bromide ion at an unactivated carbon position using a high-valent haloferryl intermediate. Despite more than a decade of structural and mechanistic characterization, ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a728a40cd623acf81c5442b5c8de8e25
https://europepmc.org/articles/PMC10245910/
https://europepmc.org/articles/PMC10245910/
Autor:
R. Hunter Wilson, Sourav Chatterjee, Elizabeth R. Smithwick, Joe J. Dalluge, Ambika Bhagi-Damodaran
Chemo- and regio-selective catalysis of C(sp3)-H halogenation reaction is a formidable goal in chemical synthesis. 2-oxo-glutarate (2OG) dependent non-heme iron halogenases catalyze selective chlorination/bromination of C-H bonds and exhibit high seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d30c3478c295ec931ef59a3e2351b5a
https://doi.org/10.26434/chemrxiv-2022-61wck
https://doi.org/10.26434/chemrxiv-2022-61wck
Publikováno v:
Phys Chem Chem Phys
The non-biological 2’-deoxy-2’-fluoro-arabinonucleic acid (2’F-ANA) may be used as a valid alternative to DNA in biomedical and electronic applications because of its higher resistance to hydrolysis and nuclease degradation. However, the advant
Autor:
Rosa Di Felice, Ruijie D. Teo, David N. Beratan, Agostino Migliore, Benjamin J. G. Rousseau, Elizabeth R. Smithwick
Publikováno v:
Chem (Cambridge. Online) 5 (2019): 122–137. doi:10.1016/j.chempr.2018.09.026
info:cnr-pdr/source/autori:Teo R.D.; Rousseau B.J.G.; Smithwick E.R.; Di Felice R.; Beratan D.N.; Migliore A./titolo:Charge Transfer between [4Fe4S] Proteins and DNA Is Unidirectional: Implications for Biomolecular Signaling/doi:10.1016%2Fj.chempr.2018.09.026/rivista:Chem (Cambridge. Online)/anno:2019/pagina_da:122/pagina_a:137/intervallo_pagine:122–137/volume:5
info:cnr-pdr/source/autori:Teo R.D.; Rousseau B.J.G.; Smithwick E.R.; Di Felice R.; Beratan D.N.; Migliore A./titolo:Charge Transfer between [4Fe4S] Proteins and DNA Is Unidirectional: Implications for Biomolecular Signaling/doi:10.1016%2Fj.chempr.2018.09.026/rivista:Chem (Cambridge. Online)/anno:2019/pagina_da:122/pagina_a:137/intervallo_pagine:122–137/volume:5
Recent experiments suggest that DNA-mediated charge transport might enable signaling between the [4Fe4S] clusters in the C-terminal domains of human DNA primase and polymerase α, as well as the signaling between other replication and repair high-pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872b75f9279390e48b643015533bc7d9
http://hdl.handle.net/11577/3365114
http://hdl.handle.net/11577/3365114
Using molecular dynamics simulations and electronic structure theory, we shed light on the charge dynamics that causes the differential interaction of tumor suppressor protein p53 with the p21 and Gadd45 genes in response to oxidative stress. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5556f63bcd94b0223afe6e0dff1c0ef5
http://hdl.handle.net/11577/3365120
http://hdl.handle.net/11577/3365120
Autor:
Elizabeth R. Smithwick, David N. Beratan, Michael J. Therien, Ruijie D. Teo, Agostino Migliore, Ruobing Wang
A recently proposed oxidative damage protection mechanism in proteins relies on hole hopping escape routes formed by redox-active amino acids. We present a computational tool to identify the dominant charge hopping pathways through these residues bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d0225659497b2da4e5d698622ab932
http://hdl.handle.net/11577/3365113
http://hdl.handle.net/11577/3365113
Publikováno v:
Anti-inflammatoryanti-allergy agents in medicinal chemistry. 16(1)
Background: Antibodies constitute an important drug development platform for drugs to treat several ophthalmic, oncologic, and immunologic conditions, but due to limitations inherent in antibody production and structure, a wide range of other protein
Autor:
Joanna McFarlane, Valmor de Almeida, Johney Green, Stuart Daw, Kalyan Chakravarthy, Sam Lewis, Scott Sluder, Bill Steele, Robert Wagner, Rolf Reitz, Gary Bell, Rick Battiste, Ralph Dinwiddie, Sam Sham, Panos Datskos, Nickolay Lavrik, Barton Smith, Viviane Schwartz, Costas Tsouris, Claus Daniel, Leon Tolbert, Madhu Chinthavali, Burak Ozpineci, Fran Li, John Kueck, Michael Starke, Hui Zhang, Yan Xu, David DePaoli, Alicia Compere, William Griffith, Chaitanya Narula, Arpad Vass, Luis Sanchez, Joel McDuffee, Jess Gehin, Randy Hobbs, Larry Ott, Lance Snead, Donald Spellman, Dennis Heatherly, Ronald Ellis, Kenneth Thoms, Sheng Dai, Huimin Luo, Gary Baker, Todd Toops, C. Britton, G. Alley, M. Ericson, R. Warmack, S. Retterer, Glenn Young, Bernadetta Srijanto, Chad Duty, Ron Ott, Philip Boudreaux, Adrian Sabau, Gerald Jellison, Curt Maxey, Keith Leonard, Biswajit Das, Volker Urban, Kunlun Hong, Phillip Britt, Jimmy Mays, Alexander Boeker, Miroslaw Gruszkiewicz, Ariel Chialvo, David Cole, Michael Simonson, Douglas Goeringer, Gary Van Berkel, Vilmos Kertesz, William Whitten, Robert Shaw, G. Stocks, Amit Goyal, Jianxin Zhong, Yanfei Gao, Albina Borisevich, Niels Jonge, Andrew Lupini, Stephen Pennycook, Gabriel Veith, Ho Lee, Matthew Chisholm, David Singh, Sergei Kalinin, Gilbert Brown, Ilia Ivanov, Stephen Jesse, David Hoelzer, James Bentley, Chong Fu, Michael Miller, Xingqiu Chen, Xun-Li Wang, Benjamin Hay, Jeremy Jackson, David Geohegan, Gernot Rother, Petro Maksymovych, Vincent Meunier, J. Wendelken, Zhenyu Zhang, Gyula Eres, M. Paranthaman, Baohua Gu, Wenguang Zhu, A. Buchanan III, Michelle Kidder, Reza Dabestani, Edward Hagaman, Minghu Pan, John Ankner, Mark Dadmun, S. Kilbey II, John Simpson, Nancy Dudney, Karren More, Ed Hagaman, Bob Shaw, De-en Jiang, Andrew Payzant, Edgar Lara-Curzio, Charles Collier, Seung-Yong Jung, Scott Retterer, Zhiyu Hu, Mark Buckner, Michael Moore, Michael Vann, Nageswara Rao, Lawrence MacIntryre, Miljko Bobrek, Benjamin Huey, Donald Bouldin, A. Qualls, B. Sumpter, S. Labinov, John Neal, Lynn Boatner, Slobodan Rajic, Mallikarjun Shankar, Yu Jiao, Ryan Kerekes, Rick Lusk, Thomas Potok, Timothy Rhyne, Vladimir Protopopescu, William Heller, Yiming Mo, Dean Myles, Greg Smith, Eugene Mamontov, Peter Cummings, Kenneth Herwig, Louis Santodonato, J. Ankner, J. Mays, J. Messman, D. Myles, B. Lokitz, Liyuan Liang, Wei Wang, Alex Johs, Hugh O’Neill, Edward Snell, Chris Tulk, Antonio Dos Santos, Jamie Molaison, Bryan Chakoumakos, Juske Horita, Dave Cole, Robert Welton, F. Baity, Richard Goulding, Andrew Christianson, Sheila Baker, Mark Lumsden, Stephen Nagler, Brian Sales, Thomas Schulthess, Thomas McManamy, Roy Crawford, Phillip Ferguson, James Janney, Mark Rennich, Leighton Coates, Flora Meilleur, Randy Fishman, Lee Robertson, Jian Shen, Wei-Ren Chen, Gregory Smith, William Goddard, Yi Liu, Yun Liu, Lionel Porcar, Pratul Agarwal, Edward Michaud III, Carmen Foster, Martin Keller, Zamin Yang, Amudhan Venkateswaran, Mircea Podar, Christopher Schadt, Steven Brown, Shihui Yang, Timothy Tschaplinski, Dale Pelletier, Gregory Hurst, Yunfeng Yang, Udaya Kalluri, Timothy McKnight, Jennifer Morrell-Falvey, Patricia Lankford, Sara Jawdy, A. Borole, Anthony Palumbo, Nance Ericson, Jeremy Smith, Elissa Chesler, Virginia Dale, Latha Baskaran, Budhendra Bhaduri, Robin Graham, Richard Middleton, Patrick Mulholland, Esther Parish, Alexandre Sorokine, Amy Wolfe, Thomas Wilbanks, Auroop Ganguly, Anthony King, David Erickson, Keith Kline, Sherry Wright, Hector Castro-Gonzalez, Marie De Graaff, Charles Garten III, Aimee Classen, Paul Hanson, Stan Wullschleger, Richard Norby, Kenneth Childs, Warren Thomas, Brynn Voy, Ram Datar, Olaf Storaasli, Edoardo Apra, Jerzy Bernholc, Robert Harrison, William Shelton, Bobby Sumpter, Sudharshan Vazhkudai, John Cobb, Xiaosong Ma, Stephen Scott, Hong Ong, Christian Engelmann, Geoffroy Vallee, Ricky Kendall, Ron Brightwell, Barney Maccabe, T. Schulthess, M. Eisenbach, D. Nicholson, X. Tao, C. Zhou, J. Levesque, Andrey Gorin, Nabeela Ahmad, Andrew Bordner, Jessie Gu, Guruprasad Kora, Chongle Pan, Byung-Hoon Park, Nagiza Samatova, Xiuping Tao, Edward Uberbacher, Kalyan Perumalla, Sudip Seal, Jeffrey Vetter, Srikanth Yoginath, Srdjan Simunovic, Phani Nukala, Kevin Clarno, Ian Gauld, Theodore Besmann, Charles Weber, Warren Grice, Ryan Bennink, Philip Evans, Travis Humble, David Bernholdt, Richard Barrett, Wael Elwasif, Aniruddha Shet, John Drake, J. White III, R. Archibald, J. Drake, K. Evans, D. Kothe, P. Worley, Jim Kohl, Doug Lepro, Dude Neergaard, Thomas Maier, Gonzalo Alvarez, Jeremy Meredith, Michael Summers, Mark Bannister, Robert Hettich, Charles Vane, Charles Havener, Herbert Krause, Michael Fogle, Jr., David Schultz, Robert Continetti, Mats Larsson, Richard Thomas, Mitchel Doktycz, David Allison, Thomas Thundat, Christopher Rey, Abhijeet Borole, Ali Passian, Yisong Wang, Yie Liu, Henry Lin, Boyd Evans, Siyang Zheng, Jason Fowlkes, Philip Rack, James Lee, Barbara Evans, Peter Reilly, Elias Greenbaum, Sylvia McLain, David Baker, Chengdu Liang, Jane Howe, Jun Xu, Radu Custelcean, Steve Overbury, Seth Cohen, Richard Ward, Kara Kruse, James Nutaro, Barbara Beckerman, Oscar Grandas, Xiaohui Cui, B. Radhakrishnan, X.-G. Zhang, An-Ping Li, N. Kulkarni, Shannon Mahurin, Meng-Dawn Cheng, David Gossage, Bruce Wilson, T. Yin, L. Gunter, Ken Littrell, Hassina Bilheux, D. Bjornstad, A. Wolfe, Jeff Warren, Timothy Bigelow, John Caughman, John McKeever, Philip Ryan, Matthew Scudiere, Gary Alley, Nagraj Kulkarni, Hsin Wang, Harry Meyer, Bala Radhakrishnan, Don Nicholson, Peter Todd, Kenneth Tobin, Vincent Paquit, Jeffery Price, John Jansen, Lonnie Love, Peter Lloyd, Christopher Mann, Philip Bingham, John Biggerstaff, Michael Zemel, Brian D’Urso, Randy Lind, Justin Baba, Seung Lee, S. Rajic, P. Datskos, Fernando Reboredo, Chengjun Sun, Xiaoguang Zhang, David Mandrus, C. Narula, M. Moses-DeBusk, A. Buchanan, C. Hsueh, P. Becher, C. Liu, John Wang, Narendra Dahotre, Seokho Kim, Peter Blau, Steve Pawel, Hans Christen, Joachim Schneibel, Michael Brady, Terry Tiegs, John Vitek, J. Horton, Ken Liu, Dan Naus, I. Wright, Lance. Snead, Thak Byun, Roger Miller, B. Bischoff, K. Adcock, Evan Ohriner, Donald Erdmann III, Katyayani Seal, James Haynes, Bruce Pint, Pengcheng Dai, Zheng Gai, Lifeng Yin, Y. Melnichenko, G. Wignall, D. Cole, A. Radlinski, M. Mastalerz, C. Alexander, R. Smithwick, L. Lewis, L. Boatner, Juan Ferrada, Jack Collins, Les Dole, Charles Forsberg, M. Haire, Rodney Hunt, Ben Lewis, Ray Wymer, Jennifer Ladd-Lively, Michael Hu, Lei Shao, Hatice Akkurt, Keith Eckerman, Ida Lee, Sotira Yiacoumi, Daniel Hollenbach, D. Dean, M. Ramsey-Musolf, Michael Smith, Eric Lingerfelt, Kim Buckner, Caroline Nesaraja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0f142d07e120361728366e8603c441c
https://doi.org/10.2172/1170191
https://doi.org/10.2172/1170191
Thesis (M.S.)--Pennsylvania State University, 2009.
Mode of access: World Wide Web. Thesis advisor: Erica A.H. Smithwick.
Mode of access: World Wide Web. Thesis advisor: Erica A.H. Smithwick.