Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R. Scott Frayo"'
Publikováno v:
Am J Physiol Endocrinol Metab
We studied the effects of multiple cycles of weight loss and regain on the defended body weight in rats. Thirty-six male Wistar rats were divided into three weight-matched groups: weight cyclers ( n = 18), ad libitum-fed controls ( n = 9), and maturi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63be634e130d1e735d8179cb4ec0d5b7
https://doi.org/10.1152/ajpendo.00110.2019
https://doi.org/10.1152/ajpendo.00110.2019
Publikováno v:
The Journal of Pediatrics. 149:199-204
To explore the hypothesis that high ghrelin levels contribute to obesity in Prader-Willi syndrome (PWS), we assessed whether the increased levels observed in older persons with PWS exist in very young children, before the onset of hyperphagia.We meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef7220d312c6874cae59972e80db4fc
https://doi.org/10.1016/j.jpeds.2006.04.011
https://doi.org/10.1016/j.jpeds.2006.04.011
Autor:
Charles Spiekerman, David S. Weigle, R. Scott Frayo, David E. Cummings, Holly S. Callahan, Colleen C. Matthys, Michi Yukawa
Publikováno v:
Journal of the American Geriatrics Society. 54:648-653
OBJECTIVES: To determine whether the failure of the orexigenic hormone ghrelin to increase as it normally does with weight loss contributes to impaired weight recovery in older persons. DESIGN: Prospective diet intervention study. SETTING: University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1da82d849aa60f0b5d1673a425060a61
https://doi.org/10.1111/j.1532-5415.2006.00689.x
https://doi.org/10.1111/j.1532-5415.2006.00689.x
Publikováno v:
Endocrinology. 146:845-850
The orexigenic hormone ghrelin is implicated in preprandial hunger and meal initiation in part because circulating levels increase before meals and decrease after food intake. The mechanisms underlying postprandial ghrelin suppression are unknown. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3524aad6207b62bc0dae1eed8ca3ec
https://doi.org/10.1210/en.2004-0609
https://doi.org/10.1210/en.2004-0609
Autor:
David E. Cummings, Karen E. Foster-Schubert, Robert S. Schwartz, Kumar B. Rajan, R. Scott Frayo, Anne McTiernan, Yutaka Yasui, Shelley S. Tworoger
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 90:820-825
Weight loss resulting from decreased caloric intake raises levels of the orexigenic hormone, ghrelin. Because ingested nutrients suppress ghrelin, increased ghrelin levels in hypophagic weight loss may result from decreased inhibitory input by ingest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16b3223f760f8a049b73d906e71a435
https://doi.org/10.1210/jc.2004-2081
https://doi.org/10.1210/jc.2004-2081
Autor:
Gregory J. Morton, David E. Cummings, Brent E. Wisse, Kayoko Ogimoto, Michael W. Schwartz, R. Scott Frayo, Charles W. Wilkinson
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 287:E1107-E1113
Interleukin-1β (IL-1β) is synthesized in a variety of tissues, including the hypothalamus, where it is implicated in the control of food intake. The current studies were undertaken to investigate whether hypothalamic IL-1β gene expression is subje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c23de4a4786dac96f838653d0f57f9d
https://doi.org/10.1152/ajpendo.00038.2004
https://doi.org/10.1152/ajpendo.00038.2004
Autor:
Katherine L. Pratt, Stephen H. LaFranchi, Jonathan Q. Purnell, Andrea M. Haqq, Ron G. Rosenfeld, David E. Cummings, Diane D. Stadler, David S. Weigle, R. Scott Frayo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:3573-3576
Prader-Willi syndrome (PWS) is characterized by severe obesity, hyperphagia, hypogonadism, and GH deficiency. Unlike individuals with common obesity, who have low fasting-plasma ghrelin concentrations, those with PWS have high fasting-ghrelin concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4ffa6ac1e9c1183998e13cd6f94925
https://doi.org/10.1210/jc.2003-030205
https://doi.org/10.1210/jc.2003-030205
Plasma levels of the orexigenic hormone ghrelin are suppressed by meals with an efficacy dependent on their macronutrient composition. We hypothesized that heterogeneity in osmolarity among macronutrient classes contributes to these differences. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b5d495752883b92b8fda30e51a88c0
https://europepmc.org/articles/PMC4059977/
https://europepmc.org/articles/PMC4059977/
Autor:
David S. Weigle, R. Scott Frayo, Brent E. Wisse, David E. Cummings, Jonathan Q. Purnell, Karin Schmidova
Publikováno v:
Diabetes. 50:1714-1719
The recently discovered orexigenic peptide ghrelin is produced primarily by the stomach and circulates in blood at levels that increase during prolonged fasting in rats. When administered to rodents at supraphysiological doses, ghrelin activates hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3362d2815b8d621801ddfeeacf4bc32
https://doi.org/10.2337/diabetes.50.8.1714
https://doi.org/10.2337/diabetes.50.8.1714
Autor:
Michi, Yukawa, David E, Cummings, Colleen C, Matthys, Holly S, Callahan, R Scott, Frayo, Charles F, Spiekerman, David S, Weigle
Publikováno v:
Journal of the American Geriatrics Society. 54(4)
To determine whether the failure of the orexigenic hormone ghrelin to increase as it normally does with weight loss contributes to impaired weight recovery in older persons.Prospective diet intervention study.University of Washington Medical Center f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35fc1ca00ec505e71a75c0102722f7c0
https://pubmed.ncbi.nlm.nih.gov/16686877
https://pubmed.ncbi.nlm.nih.gov/16686877