Zobrazeno 1 - 10
of 5 657
pro vyhledávání: '"R. Sah"'
Autor:
Joakim W Karlsson, Vasu R Sah, Roger Olofsson Bagge, Irina Kuznetsova, Munir Iqba, Samuel Alsen, Sofia Stenqvist, Alka Saxena, Lars Ny, Lisa M Nilsson, Jonas A Nilsson
Publikováno v:
eLife, Vol 12 (2024)
Uveal melanoma (UM) is a rare melanoma originating in the eye’s uvea, with 50% of patients experiencing metastasis predominantly in the liver. In contrast to cutaneous melanoma, there is only a limited effectiveness of combined immune checkpoint th
Externí odkaz:
https://doaj.org/article/c4cf816d012540229735b294db77459e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype with the most unfavorable clinical outcomes, in part due to tumor heterogeneity, treatment resistance, and tumor relapse. The TNBC subtypes [basal-like 1 (BL1), basal-like 2 (B
Externí odkaz:
https://doaj.org/article/cc89dfb3e78e40f3886ef428e2aabab0
Autor:
Lars Ny, Henrik Jespersen, Joakim Karlsson, Samuel Alsén, Stefan Filges, Charlotta All-Eriksson, Bengt Andersson, Ana Carneiro, Hildur Helgadottir, Max Levin, Ingrid Ljuslinder, Roger Olofsson Bagge, Vasu R. Sah, Ulrika Stierner, Anders Ståhlberg, Gustav Ullenhag, Lisa M. Nilsson, Jonas A. Nilsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The authors report the results of the phase II PEMDAC clinical study testing the combination of the HDAC inhibitor entinostat with the anti- PD-1 antibody pembrolizumab in uveal melanoma. Low tumor burden, a wildtype BAP1 gene in the tumor or iris me
Externí odkaz:
https://doaj.org/article/81ef06cf1a674812b72c3509644a228b
Autor:
Joakim Karlsson, Lisa M. Nilsson, Suman Mitra, Samuel Alsén, Ganesh Vilas Shelke, Vasu R. Sah, Elin M. V. Forsberg, Ulrika Stierner, Charlotta All-Eriksson, Berglind Einarsdottir, Henrik Jespersen, Lars Ny, Per Lindnér, Erik Larsson, Roger Olofsson Bagge, Jonas A. Nilsson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The genetics of uveal melanoma has mainly been studied in primary tumours. In this study, the authors perform whole genome sequencing as well as immune cell profiling of biopsy samples obtained from metastatic uveal melanoma patients, providing an up
Externí odkaz:
https://doaj.org/article/f71cb61f5c524059bea90c9e29676365
Autor:
Vasu R. Sah, Henrik Jespersen, Joakim Karlsson, Lisa M. Nilsson, Mattias Bergqvist, Iva Johansson, Ana Carneiro, Hildur Helgadottir, Max Levin, Gustav Ullenhag, Anders Ståhlberg, Roger Olofsson Bagge, Jonas A. Nilsson, Lars Ny
Publikováno v:
Cancer Research Communications. 3:884-895
Purpose: Patients with metastatic uveal melanoma have limited therapeutic options and high mortality rate so new treatment options are needed. Patients and Methods: We previously reported that patients treated with the PD-1 inhibitor pembrolizumab an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f61ee2b2a9e060e7ab5e3f00bcbb746
https://doi.org/10.1158/2767-9764.crc-22-0490
https://doi.org/10.1158/2767-9764.crc-22-0490
Publikováno v:
Journal of Agriculture and Forestry University. :209-217
Udder and teat conformations and measurements play a vital role in milk productivity and mastitis resistance in dairy buffaloes. The study was conducted on apparently healthy 24 Murrah buffaloes running on different parities selected from 3 different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e66356291a9c38620588b2378f8b0f38
https://doi.org/10.3126/jafu.v5i1.48467
https://doi.org/10.3126/jafu.v5i1.48467
Autor:
Lars Ny, Jonas A. Nilsson, Roger Olofsson Bagge, Anders Ståhlberg, Gustav J. Ullenhag, Max Levin, Hildur Helgadottir, Ana Carneiro, Iva Johansson, Mattias Bergqvist, Lisa M Nilsson, Joakim Karlsson, Henrik Jespersen, Vasu R Sah
Figure S3. a) Heat map showing plasma chemokine and cytokine levels pre-treatment to end of study (EOS) in patients with progressive disease (PD) b) Heat map of plasma chemokine levels pre-treatment to EOS in stable disease (SD) patients. c) Heat map
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6097685a6839e4a81802794abbfe1944
https://doi.org/10.1158/2767-9764.22930538
https://doi.org/10.1158/2767-9764.22930538
Autor:
Lars Ny, Jonas A. Nilsson, Roger Olofsson Bagge, Anders Ståhlberg, Gustav J. Ullenhag, Max Levin, Hildur Helgadottir, Ana Carneiro, Iva Johansson, Mattias Bergqvist, Lisa M Nilsson, Joakim Karlsson, Henrik Jespersen, Vasu R Sah
Purpose:Patients with metastatic uveal melanoma have limited therapeutic options and high mortality rate so new treatment options are needed.Patients and Methods:We previously reported that patients treated with the PD-1 inhibitor pembrolizumab and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccdda0f37fdea4ebde8dc4703e012e9
https://doi.org/10.1158/2767-9764.c.6628509
https://doi.org/10.1158/2767-9764.c.6628509
Autor:
Lars Ny, Jonas A. Nilsson, Roger Olofsson Bagge, Anders Ståhlberg, Gustav Ullenhag, Max Levin, Hildur Helgadottir, Ana Carneiro, Iva Johansson, Mattias Bergqvist, Lisa M. Nilsson, Joakim Karlsson, Henrik Jespersen, Vasu R. Sah
Kaplan–Meier analysis showing. PFS (A) and OS (B), respectively using pretreatment plasma CCL21 (pg/mL) measurements based on their median values. C, Correlation between CCL21 (pg/mL) and CD3+CCR7+CD45RA+ (% counts) matched patient samples (n = 23)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc75b67b510f17ed10f776715ff10ecd
https://doi.org/10.1158/2767-9764.22930553
https://doi.org/10.1158/2767-9764.22930553