Zobrazeno 1 - 5
of 5
pro vyhledávání: '"R. S. Wexler"'
Publikováno v:
Anticancer research. 21(2A)
The hollow fiber assay presents a potentially unique tool to study the effects of regulated gene expression in cell lines that do not form tumors in vivo. The hollow fibers allow small molecules to pass freely through while keeping the cells within t
Publikováno v:
Anticancer research. 20(2A)
The hollow fiber assay, a unique in vivo model, permits the simultaneous evaluation of compound efficacy against multiple cell lines in two physiological compartments. This assay has been used to characterize in vivo activity of cytotoxic compounds.
Autor:
J S, Kerr, R S, Wexler, S A, Mousa, C S, Robinson, E J, Wexler, S, Mohamed, M E, Voss, J J, Devenny, P M, Czerniak, A, Gudzelak, A M, Slee
Publikováno v:
Anticancer research. 19(2A)
Recent evidence supports the involvement of integrins in angiogenesis: blockade of alpha v beta 3 and alpha v beta 5 integrins disrupts angiogenesis leading to decreased blood vessel formation and hence decreased tumor growth. We hypothesized that av
Autor:
H M, DeLisser, M, Christofidou-Solomidou, R M, Strieter, M D, Burdick, C S, Robinson, R S, Wexler, J S, Kerr, C, Garlanda, J R, Merwin, J A, Madri, S M, Albelda
Publikováno v:
The American journal of pathology. 151(3)
The adhesive interactions of endothelial cells with each other and the adhesion receptors that mediate these interactions are probably of fundamental importance to the process of angiogenesis. We therefore studied the effect of inhibiting the functio
Autor:
C. Winter, A. Seeley, S. Jha, G. Naumov, R. S. Wexler, Andrew Bloecher, Sriram Sathyanarayanan, S. Howard, John F. Reilly, Erin Valentine, H. Keihack
Publikováno v:
Journal of Clinical Oncology. 29:e13590-e13590
e13590 Background: Rational combination of 2 or more investigational compounds is a novel concept in oncology. We have entered phase I clinical development in patients with solid tumors with novel ...