Zobrazeno 1 - 10
of 27
pro vyhledávání: '"R. S. Sukasyan"'
Autor:
A. I. Markosyan, N. P. Grigoryan, R. S. Sukasyan, R. G. Paronikyan, A. S. Grigoryan, G. A. Stepanyan
Publikováno v:
Pharmaceutical Chemistry Journal. 51:1057-1062
A synthetic method for 7,10-dimethyl-2-thioxo-2,3-dihydro-1H-spiro[benzo[h]quinazoline-5,1′-cyclopentane]- 4(6H)-one from ethyl 4′-amino-5′,8′-dimethyl-1′-H-spiro[cyclopentane-1,2′-naphthalene]-3′-carboxylate was developed. Reaction of
Publikováno v:
Pharmaceutical Chemistry Journal. 51:635-640
7,10-Dimethyl-2-thioxo-2,3-dihydro-1H-spiro[benzo[h]quinazoline-5,1′-cyclohexane]-4(6H)-one was synthesized from ethyl 4′-amino-5′,8′-dimethyl-1′H-spiro[cyclohexane-1,2′-naphthalene]-3′-carboxylate and reacted with various alkyl(benzyl)
Autor:
A. S. Grigoryan, A. A. Harutyunyan, A. G. Aivazyan, R. V. Paronikyan, S. G. Chishmarityan, Rafael Tamazyan, G. A. Panosyan, R. S. Sukasyan, H. M. Stepanyan
Publikováno v:
Russian Journal of Organic Chemistry. 51:711-714
Heating a mixture of substituted malonic esters and 6-methoxy-1,3-benzothiazolyl-2-amine afforded new derivatives of benzo[4,5]thiazolo[3,2-a]pyrimidine, 3-substituted 2-hydroxy-4H-benzo[4,5]-thiazolo[3,2-a]pyrimidine-4-ones. The choice between the p
Publikováno v:
Pharmaceutical Chemistry Journal. 48:783-786
2-Sulfanyl-substituted 3-ethyl-3H-spiro[benzo[h]quinazolin-5,1-cyclohexane]-4(6H)-ones were synthesized by reacting 3-ethyl-2-thioxo-2,3-dihydro-1H-spiro[benzo[h]quinazolin-5,1-cyclohexane]-4(6H)-one with halides. 2-Hydrazino-3-ethyl-3H-spiro[benzo[h
Publikováno v:
Pharmaceutical Chemistry Journal. 48:368-372
Amides that cyclized into 2-substituted 3H-spiro[benzo(h)quinazoline-5,1′-cyclohexane]-4(6H)-ones were prepared by reaction of 4′-amino-1′H-spiro[cyclohexane-1,2′-naphthalene]-3′-nitrile with carboxylic acid chlorides. Substitution of the b
Publikováno v:
Pharmaceutical Chemistry Journal. 45:79-83
Ethyl 2-cyano-3-cyclohexyl-3-methyl-4-phenylbutanoate was synthesized from ethyl (2Z)-2-cyano-3cyclohexylbut-2-enoate using a Grignard reagent. It was shown that the reaction occurred exclusively at the ethylene bond. Because this cyanoester containe
Publikováno v:
Pharmaceutical Chemistry Journal. 44:409-412
The condensation of 4-amino-3-cyano-1,2-dihydrospiro(naphthalene-2,1'-cyclopentane) with y-chlorobutyryl chloride and aromatic acid chlorides yielded amides that were cyclized into 2-substituted 4-oxo3,4,5,6-tetrahydrospiro(benzo[h]quinazoline-5,1'-c
Publikováno v:
Pharmaceutical Chemistry Journal. 44:405-408
Reaction of 4-amino-3-ethoxycarbonyl-1,2-dihydrospiro(naphthalene-2,1'-cyclohexane) with allylisothiocyanate was used to synthesize 3-allyl-4-oxo-2-thioxo-1,2,3,4,5,6-hexahydrospiro(benzo[h]quinazoline5,1'-cyclohexane). Condensation of the latter wit
Autor:
R. S. Sukasyan, S. V. Dilanyan, B. T. Garibdzhanyan, F. G. Arsenyan, S. A. Gabrielyan, A. I. Markosyan
Publikováno v:
Pharmaceutical Chemistry Journal. 44:352-355
N'-{[(2-cyano-3-ethyl-3-methyl-3, 4-dihydronaphthalen-1-yl)amino]carbonothionyl}benzamide (II) was synthesized by reaction of 1-amino-3-ethyl-3-methyl-3,4-dihydronaphthalene-2-carbonitrile (aminonitrile I) with benzoylisothiocyanate. Condensation of
Autor:
S. V. Dilanyan, I. S. Sarkisyan, B. T. Garibdzhanyan, A. I. Markosyan, R. S. Sukasyan, F. G. Arsenyan
Publikováno v:
Pharmaceutical Chemistry Journal. 44:111-114
The interaction of 1-amino-3-methyl-3-ethyl-3,4-dihydronaphthaline-2-carbonitrile (I) with propanoic acid chloranhyride was used to synthesize the corresponding amidonitrile II, which was then cyclized to form 2,5-diethyl-5-methyl-4-oxo-5,6-dihydrobe