Zobrazeno 1 - 10
of 43
pro vyhledávání: '"R. S. Redman"'
Publikováno v:
Drug Development Research. 52:22-33
ATP is released from many central and peripheral terminals in a rapid, synch'onous manner. It can act both as a neurotransmitter substance and as a neuromodulator in conjunction with a primary neurotransmitter. We begin this perspective by reviewing
Publikováno v:
The Journal of Physiology. 510:783-791
1. The interaction of ion channels activated by nicotinic receptor agonists with ion channels gated by extracellular ATP (i.e. P2X receptors) was studied on sympathetic neurons acutely dissociated from coeliac ganglia of the guinea-pig. Patch clamp m
Publikováno v:
Hepatology. 25:1451-1456
Various lipid parameters were determined in lean control and LA/NIH-corpulent (LA/N-cp) rats, a normotensive strain showing metabolic characteristics associated with human Type IV hyperlipidemia. Hepatic and plasma total cholesterol, high density lip
Publikováno v:
The Journal of Physiology. 501:41-48
1 Phorbol esters activate protein kinase C (PKC) and also increase the secretion of neuro-transmitter substances by an unknown mechanism. To evaluate whether the stimulatory effects of such agents on acetylcholine (ACh) secretion occur as a consequen
Autor:
N L McCartney-Francis, D E Mizel, R S Redman, M Frazier-Jessen, R B Panek, A B Kulkarni, J M Ward, J B McCarthy, S M Wahl
Publikováno v:
The Journal of Immunology. 157:1306-1312
The targeted disruption of the TGF-beta1 gene in mice (TGF-beta1 -/-) leads to extensive inflammation in vital organs, cachexia, and death within 3 to 4 wk. Significant inflammatory lesions develop initially in the periductal regions of the salivary
Autor:
R. S. Redman, Eugene M. Silinsky
Publikováno v:
The Journal of Physiology. 492:815-822
1. It has been suggested that ATP is released together with the neurotransmitter acetylcholine (ACh) and, after hydrolysis to adenosine, is the primary physiological mediator of prejunctional neuromuscular depression. To evaluate whether ATP is relea
Autor:
R. S. Redman, Eugene M. Silinsky
Publikováno v:
British Journal of Pharmacology. 113:375-378
1. The effects of the aminoglycoside antibiotics, streptomycin, neomycin and gentamicin were examined on perineural currents and evoked acetylcholine (ACh) release at frog motor nerve endings. 2. In the standard solutions used previously to measure C
Publikováno v:
Peptides. 15:855-860
Structure-activity relationships were determined for the natural bag cell peptides (BCPs) and for a series of synthetic analogues in terms of their ability to stimulate (at 30°C) and to inhibit (at 15°C) bag cell adenyl cyclase. We found that the c
Autor:
Robert W. Berry, R. S. Redman
Publikováno v:
Molecular Brain Research. 8:99-103
alpha-Bag cell peptide (alpha-BCP), one of several secreted peptides encoded in the precursor to the egg-laying hormone (proELH) of the neurosecretory bag cells of Aplysia, has been variously reported to have autoexcitatory or autoinhibitory effects
Publikováno v:
The Histochemical Journal
In examining the secretory mechanism of exocrine glands, we focused on the small GTP-binding proteins, Rab3D and Rab3B, which function in the final steps of exocytosis in non-neuronal tissues. These proteins were observed in von Ebner's glands by 32P