Zobrazeno 1 - 10
of 11
pro vyhledávání: '"R. S. Paules"'
Autor:
Jennifer B. Collins, S. O. Sieber, Joan P. Graves, Darryl C. Zeldin, F. Xu, John M. Seubert, Deanna L. Kroetz, R. S. Paules
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F552-F561
Development of hypertension stems from both environmental and genetic factors wherein the kidney plays a central role. Spontaneously hypertensive rats (SHR) and the nonhypertensive Wistar-Kyoto (WKY) controls are widely used as a model for studying h
Autor:
Geetha M. Habib, Michael W. Lieberman, Mahara Valverde, Emilio Rojas, R. S. Paules, Zheng-Zheng Shi
Publikováno v:
BioFactors. 17:13-19
Autor:
R S, Paules
Publikováno v:
La Medicina del lavoro. 97(2)
Publikováno v:
Free radical biologymedicine. 28(9)
Oxidative stress and the damage that results from it have been implicated in a wide number of disease processes including atherosclerosis, autoimmune disorders, neuronal degeneration, and cancer. Reactive oxygen species (ROS) are ubiquitous and occur
Publikováno v:
Cancer research. 59(21)
It has been suggested that the cellular response to exposure to ionizing radiation involves activation of the transcription factor nuclear factor-kappaB (NF-kappaB) and that this response is defective in cells from individuals with ataxia telangiecta
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(10)
Chromosomal stability was linked to G2 checkpoint function in human fibroblasts expressing the human papillomavirus type 16 E6 oncoprotein. Soon after expression of E6, cells displayed an undamaged, diploid karyotype and normal mitotic delay after ga
Publikováno v:
Cancer research. 55(12)
We have previously reported that the immediate G2 checkpoint delay of normal human fibroblasts in response to ionizing radiation is correlated with inhibition of p34CDC2/cyclin B kinase activity. Here, we observed increased amounts of the cyclin-depe
Publikováno v:
Cancer research. 55(1)
We have investigated the hypothesis that attenuation of the G2 checkpoint, which delays entry into mitosis in response to damage to DNA and protects against clastogenesis, may contribute to the genetic instability of immortal human cell lines. IMR-90
Publikováno v:
Oncogene. 7(12)
We have characterized the mouse Mos proto-oncogene product, pp39Mos, in murine fibroblasts. When expressed in NIH3T3 cells under the influence of the long terminal repeat regulatory element from Moloney murine sarcoma virus [NIH(pTS-1) cells], the Mo
Autor:
N, Schulz, F, Propst, M P, Rosenberg, R I, Linnoila, R S, Paules, R, Kovatch, Y, Ogiso, G, Vande Woude
Publikováno v:
Cancer research. 52(2)
Transgenic mice carrying and expressing a mos protooncogene, linked to the Moloney murine sarcoma virus long terminal repeat, develop severe neurological defects and lens abnormalities. Here we report that after long latent periods, mice in three of