Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R. S. Agabekyan"'
Publikováno v:
ChemInform. 21
Autor:
M. I. Kabachnik, M. Kh. Bekanov, N. N. Godovikov, L. G. Grineva, L. M. Zakharova, M. Kh. Berkhamov, R. S. Agabekyan, V. M. Kuzamyshev, G. G. Ol'khovaya
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 30:658-663
1. The anticholinesterase activity has been determined for a series of synthesized S-β-aryl- and S-β-benzylmercaptoethyl thiophosphonates and thiophosphates with respect to acetylcholinesterase of human blood erythrocytes (EC 3.1.1.7) and butyrylch
Autor:
V. N. Muzykantova, V. M. Kuzamyshev, M. I. Kabachnik, M. Kh. Bekanov, N. N. Godovikov, R. S. Agabekyan, M. Kh. Berkhamov
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 26:1730-1734
1. The reaction of 0-ethyl-S-(β-alkylmercaptoethyl)benzylthiophosphonates and their iodomethylates with acetylcholinesterase and butyrylcholinesterase has been studied. 2. 0-ethyl-S-(β-alkylmercaptoethyl)benzylthiophosphonates are inhibitors of the
Autor:
V. M. Kuzamyshev, M. Kh. Berkhamov, N. N. Godovikov, R. S. Agabekyan, E. G. Kireeva, Z. K. Pegova, M. I. Kabachnik
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 26:1471-1476
Synthesis and anticholinesterase properties of some S-benzhydryl esters of phosphorus monothio acids
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 26:2153-2157
1. Alkylation of salts of phosphorus monothio acids with diphenylbromomethane in benzene forms S-benzhydryl esters of the corresponding phosphorus monothio acids with concomitant formation of the O-benzhydryl esters (
Autor:
E. G. Kireeva, R. S. Agabekyan, M. Kh. Berkhamov, V. G. Zhasminova, V. M. Kuzamyshev, Kh. Kh. Gurdaliev, M. I. Kabachnik, N. N. Godovikov
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 26:1939-1942
1. A number of O-ethyl O-β-alkylmercaptoethyl benzylphosphonates and their methylated iodides have been synthesized. 2. The O-ethyl O-β-alkylmercaptoethyl benzylphosphonates and their methylated iodides were found to be reversible inhibitors of ace
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 23:374-377
1. A number of S-alkyl diphenylthiophosphinates was synthesized and their inhibiting activity toward acetytcholinesterase was studied. 2. The obtained compounds are capable of both reversible and irreversible inhibition of the catalytic activity of a
Synthesis and anticholinesterase properties of O-ethyl-S-(?-alkylsulfoxyethyl)methylthiophosphonates
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 23:1288-1290
1. A number of O-ethyl-S-(β-alkylsulfoxyethyl)methylthiophosphonates was synthesized. 2. The synthesized compounds are more active inhibitors than the corresponding O-ethyl-S-(β-alkylmercaptoethyl) methylthiophosphonates for acetylcholinesterase, a
Autor:
M. Kh. Berkhamov, V. M. Kuzamyshev, G. G. Ol'khovaya, R. S. Agabekyan, N. N. Godovikov, M. I. Kabachnik, M. Kh. Bekanov
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 26:1943-1945
1. The kinetics of the interaction of the methylated iodides of O-ethyl O-β-alkylmercaptoethyl phenylphosphonates and methylated iodides of O-alkyl O-β-methylmercaptoethyl phenylphosphonates with acetylcholinesterase and butyrylcholinesterase have
Autor:
L. M. Zakharova, Z. K. Pegova, R. S. Agabekyan, V. M. Kuzamyshev, N. N. Godovikov, M. I. Kabachnik, M. Kh. Berkhamov
Publikováno v:
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 26:1477-1479
O-Ethyl-O-(β-alkylmercaptoethyl)cyclohexylphosphonates and their iodomethylates are reversible acetylcholinesterase and butyrylcholinesterase inhibitors of a competitive type; their inhibitory activity increases with lengthening of the alkyl radical