Zobrazeno 1 - 10
of 148
pro vyhledávání: '"R. Roda"'
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 8, Pp 1666-1674 (2022)
Alzheimer’s disease is a neurodegenerative disease that accounts for most of the 50-million dementia cases worldwide in 2018. A large amount of evidence supports the amyloid cascade hypothesis, which states that amyloid-beta accumulation triggers t
Externí odkaz:
https://doaj.org/article/7a63f50772e94f7cb2887f0483df00b1
Akademický článek
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Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 944 (2020)
Clinical symptoms of Alzheimer’s Disease (AD) include behavioral alterations and cognitive impairment. These functional phenotypes early occur in triple-transgenic (3xTg-AD) mice. Specifically, behavioral alterations are first detected when mice ar
Externí odkaz:
https://doaj.org/article/b02ce3b98c944e2c9bf2995dc899ce9b
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6630 (2020)
Alzheimer’s disease (AD) is the most common dementia worldwide. According to the amyloid hypothesis, the early accumulation of the Aβ-peptide triggers tau phosphorylation, synaptic dysfunction, and eventually neuronal death leading to cognitive im
Externí odkaz:
https://doaj.org/article/51eb8367f7834a608d14c16cdd7a2f42
Akademický článek
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Publikováno v:
Neuromuscular Disorders. 32:S117
Publikováno v:
Pharmaceutics
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Pharmaceutics, Vol 12, Iss 944, p 944 (2020)
Volume 12
Issue 10
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Pharmaceutics, Vol 12, Iss 944, p 944 (2020)
Volume 12
Issue 10
Clinical symptoms of Alzheimer&rsquo
s Disease (AD) include behavioral alterations and cognitive impairment. These functional phenotypes early occur in triple-transgenic (3xTg-AD) mice. Specifically, behavioral alterations are first detected whe
s Disease (AD) include behavioral alterations and cognitive impairment. These functional phenotypes early occur in triple-transgenic (3xTg-AD) mice. Specifically, behavioral alterations are first detected whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34edfd8087941d8540f8592f42c9405
https://ddd.uab.cat/record/233654
https://ddd.uab.cat/record/233654
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6630, p 6630 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6630, p 6630 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Alzheimer&rsquo
s disease (AD) is the most common dementia worldwide. According to the amyloid hypothesis, the early accumulation of the A&beta
peptide triggers tau phosphorylation, synaptic dysfunction, and eventually neuronal death leadin
s disease (AD) is the most common dementia worldwide. According to the amyloid hypothesis, the early accumulation of the A&beta
peptide triggers tau phosphorylation, synaptic dysfunction, and eventually neuronal death leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30bd93eae26ca3126c63bc8bb87d7221
https://ddd.uab.cat/record/233191
https://ddd.uab.cat/record/233191
Autor:
Gabriel Serra-Mir, Alejandro R Roda, José Luis Sánchez-Quesada, Sandra Villegas, Jofre Güell-Bosch, Gisela Esquerda-Canals, Silvia Lope-Piedrafita, Laia Montoliu-Gaya
Publikováno v:
Biochemical Pharmacology. 155:380-392
Anti-Aβ immunotherapy has emerged as a promising approach to treat Alzheimer's disease (AD). The single-chain variable fragment scFv-h3D6 is an anti-Aβ antibody fragment that lacks the Fc region, which is associated with the induction of microglial
Autor:
Geovanny Rivera-Hernández, Gisela Esquerda-Canals, Laia Montoliu-Gaya, Sandra Villegas, Alejandro R Roda, Joaquim Martí-Clúa
Publikováno v:
Journal of Alzheimer's disease : JAD. 70(4)
The intracellular deposition of amyloid-β (Aβ) peptides has been described in the brains of both Alzheimer's disease (AD) patients and animal models. A correlation between the intracellular amyloid burden and neurodegeneration has recently been rep