Zobrazeno 1 - 10
of 28
pro vyhledávání: '"R. R. Koganty"'
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::291f76b6545c0eaf994106f435d8f8f5
https://doi.org/10.1002/chin.199618210
https://doi.org/10.1002/chin.199618210
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 61(3)
MUC1 mucin is a large transmembrane glycoprotein, the extracellular domain of which is formed by a repeating 20 amino acid sequence, GVTSAPDTRPAPGSTAPPAH. In normal breast epithelial cells, the extracellular domain is densely covered with highly bran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fce83281b926c6c0fa531a81bf8eb07f
https://pubmed.ncbi.nlm.nih.gov/12558945
https://pubmed.ncbi.nlm.nih.gov/12558945
Publikováno v:
Glycoconjugate journal. 17(12)
Synthetic oligosaccharide vaccines based on core STn (sialyl alpha2-6 GalNAc) carbohydrate epitopes are being evaluated by a number of biopharmaceutical firms as potential immunotherapeutics in the treatment of mucin-expressing adenocarcinomas. The S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac6b33cba270a0935099dd7f44c638cf
https://pubmed.ncbi.nlm.nih.gov/11511808
https://pubmed.ncbi.nlm.nih.gov/11511808
Publikováno v:
Cancer research. 58(22)
MHC class I molecules were isolated from the MUC1-positive human breast adenocarcinoma cell line MCF-7 by immunoaffinity using the panreactive anti-class I monoclonal antibodies (MAb) W6/32. Acid-eluted peptides from the class I molecules were separa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0209043a68c3206bf5698beb6f9a867c
https://pubmed.ncbi.nlm.nih.gov/9823326
https://pubmed.ncbi.nlm.nih.gov/9823326
Autor:
M, Reddish, G D, MacLean, R R, Koganty, J, Kan-Mitchell, V, Jones, M S, Mitchell, B M, Longenecker
Publikováno v:
International journal of cancer. 76(6)
Sixteen metastatic breast cancer patients were immunized with a low dose (5 micrograms) of a 16 amino acid MUC1 peptide (GVTSAPDTRPAPGSTA) conjugated to KLH (BP16-KLH) plus DETOX adjuvant and evaluated for antibody titers against MUC1 peptide and KLH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfdb683e0ab495836ef8c14566c6bca3
https://pubmed.ncbi.nlm.nih.gov/9626347
https://pubmed.ncbi.nlm.nih.gov/9626347
Publikováno v:
Glycoconjugate journal. 15(3)
STn (NeuAcalpha2 --6GalNAc alpha-O-Ser/Thr) is a carbohydrate epitope overexpressed in various human carcinomas. Clinical trials are underway using synthetic STn or STn trimeric glycopeptides [STn, cluster; STn(c)] conjugated with keyhole limpet hemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fa59766746cfc96e2db74bb20c9c812
https://pubmed.ncbi.nlm.nih.gov/9579798
https://pubmed.ncbi.nlm.nih.gov/9579798
Autor:
J, Samuel, W A, Budzynski, M A, Reddish, L, Ding, G L, Zimmermann, M J, Krantz, R R, Koganty, B M, Longenecker
Publikováno v:
International journal of cancer. 75(2)
A human MUC1-transfected mouse mammary adenocarcinoma cell line (GZHI) was used to develop both subcutaneous and intravenous tumor models. A vaccine formulation comprised of a 24 mer (human MUC1) synthetic peptide encapsulated with monophosphoryl lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe9ed433366bee70cb97f79ce3a351ea
https://pubmed.ncbi.nlm.nih.gov/9462722
https://pubmed.ncbi.nlm.nih.gov/9462722
Autor:
M R, Price, P D, Rye, E, Petrakou, A, Murray, K, Brady, S, Imai, S, Haga, Y, Kiyozuka, D, Schol, M F, Meulenbroek, F G, Snijdewint, S, von Mensdorff-Pouilly, R A, Verstraeten, P, Kenemans, A, Blockzjil, K, Nilsson, O, Nilsson, M, Reddish, M R, Suresh, R R, Koganty, S, Fortier, L, Baronic, A, Berg, M B, Longenecker, J, Hilgers
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 19
Sixteen research groups participated in the ISOBM TD-4 Workshop in which the reactivity and specificity of 56 monoclonal antibodies against the MUC1 mucin was investigated using a diverse panel of target antigens and MUC1 mucin-related synthetic pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74c15d63fa6e47fa918ec0ab771d0344
https://pubmed.ncbi.nlm.nih.gov/9422084
https://pubmed.ncbi.nlm.nih.gov/9422084
Publikováno v:
Glycoconjugate journal. 14(5)
The fine specificities of MAbs generated using novel synthetic clustered STn and Tn glycopeptides as immunogens were compared with the anti-TAG-72 antibodies B72.3 and CC49. Hapten inhibition experiments demonstrated the specificity of several of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ce9a5cb2c25baab61f64483a350ab70
https://pubmed.ncbi.nlm.nih.gov/9298687
https://pubmed.ncbi.nlm.nih.gov/9298687
Autor:
S, Zhang, L A, Walberg, S, Ogata, S H, Itzkowitz, R R, Koganty, M, Reddish, S S, Gandhi, B M, Longenecker, K O, Lloyd, P O, Livingston
Publikováno v:
Cancer research. 55(15)
Sialyl Tn (sTn) is a mucin-associated carbohydrate antigen expressed in most types of human adenocarcinoma. Defining the configuration of tumor cell surface sTn recognized by antibodies is important for understanding the basis for the cancer cell spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9eb3c4c51850745feb2585c51f6d170b
https://pubmed.ncbi.nlm.nih.gov/7614472
https://pubmed.ncbi.nlm.nih.gov/7614472