Zobrazeno 1 - 10 of 24 pro vyhledávání: '"R. R. Hardin"'
1
1α,25(OH)2D3 causes a rapid increase in phosphatidylinositol-specific PLC-β activity via phospholipase A2-dependent production of lysophospholipid
Autor: R. R. Hardin, Barbara D. Boyan, Scott F. Gruwell, Victor L. Sylvia, David D Dean, Zvi Schwartz, D Shaked
Publikováno v: Steroids. 68:423-437
1alpha,25(OH)(2)D(3) activates protein kinase C (PKC) in rat growth plate chondrocytes via mechanisms involving phosphatidylinositol-specific phospholipase C (PI-PLC) and phospholipase A(2) (PLA(2)). The purpose of this study was to determine if 1alp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c874c1d443a202084cd3136c915d0b28
https://doi.org/10.1016/s0039-128x(03)00044-8
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2
1α,25-Dihydroxyvitamin D3 and 24R,25-Dihydroxyvitamin D3 Modulate Growth Plate Chondrocyte Physiology via Protein Kinase C-Dependent Phosphorylation of Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase
Autor: Zvi Schwartz, D. Larsson, Barbara D. Boyan, D. Lopez, V. Bingham, David D Dean, H. Ehland, R. R. Hardin, Victor L. Sylvia
Publikováno v: Endocrinology. 143:2775-2786
Membrane-mediated increases in protein kinase C (PKC) activity and PKC-dependent physiological responses of growth plate chondrocytes to vitamin D metabolites depend on the state of endochondral maturation; 1alpha,25-dihydroxyvitamin D(3) [1alpha,25-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03e704d980a8270188af58ee87d54fa
https://doi.org/10.1210/endo.143.7.8889
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3
Regulation of phospholipase D (PLD) in growth plate chondrocytes by 24R,25-(OH)2D3 is dependent on cell maturation state (resting zone cells) and is specific to the PLD2 isoform
Autor: David D Dean, R. R. Hardin, P. DeVeau, R. Whetstone, Victor L. Sylvia, Barbara D. Boyan, Zvi Schwartz, F. Del Toro
Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1499(3):209-221
Many of the effects of 1alpha,25-(OH)2D3 and 24R,25-(OH)2D3 on costochondral chondrocytes are mediated by the protein kinase C (PKC) signal transduction pathway. 1alpha,25-(OH)2D3 activates PKC in costochondral growth zone chondrocytes through a spec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35dd8416f3f1c0086475ecf577952bb
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4
24R,25-(OH)2D3 mediates its membrane receptor-dependent effects on protein kinase C and alkaline phosphatase via phospholipase A2 and cyclooxygenase-1 but not cyclooxygenase-2 in growth plate chondrocytes
Autor: Victor L. Sylvia, David D Dean, R. R. Hardin, Barbara D. Boyan, Zvi Schwartz, F. Del Toro
Publikováno v: Journal of Cellular Physiology. 182:390-401
Recent studies have shown that 24R,25-(OH)(2)D(3) mediates its effects on growth plate chondrocytes via membrane receptors. This study examined the roles of phospholipase A(2) (PLA(2)) and cyclooxygenase (Cox) in the mechanism of action of 24R, 25-(O
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00dcef4c64889cb986eee5c874a77ca6
https://doi.org/10.1002/(sici)1097-4652(200003)182:3<390::aid-jcp10>3.0.co
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5
Expression and production of stathmin in growth plate chondrocytes is cell-maturation dependent
Autor: R. R. Hardin, Thomas W. Hummert, Barbara D. Boyan, Victor L. Sylvia, David D Dean, Zvi Schwartz
Publikováno v: Journal of Cellular Biochemistry. 79:150-163
Growth plate cartilage is comprised of linear columns of chondrocytes with the least differentiated cells at one end and the terminally differentiated cells at the other end. Rat costochondral chondrocytes can be divided into the resting cell zone (r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38e9d51c9ecc9c901487fa2c72cfb9c8
https://doi.org/10.1002/1097-4644(2000)79:1<150::aid-jcb140>3.0.co
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6
Rat costochondral chondrocytes produce 17beta-estradiol and regulate its production by 1alpha,25(OH)(2)D(3)
Autor: Zvi Schwartz, R. R. Hardin, Victor L. Sylvia, David D Dean, Barbara D. Boyan
Publikováno v: Bone. 30(1)
Prior studies have shown that 17beta-estradiol (17beta-E(2)) regulates growth plate chondrocyte maturation and differentiation. This study examines the hypothesis that 17beta-E(2) is a local regulator of rat costochondral growth plate chondrocytes by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2602c95e27100846a5f6d405bc771dc
https://pubmed.ncbi.nlm.nih.gov/11792565
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7
Effects of 1alpha,25-(OH)(2)D(3) on rat growth zone chondrocytes are mediated via cyclooxygenase-1 and phospholipase A(2)
Autor: Victor L. Sylvia, Zvi Schwartz, Barbara D. Boyan, F. Del Toro, R. R. Hardin, David D Dean
Publikováno v: Europe PubMed Central
1alpha,25-(OH)(2)D(3) mediates its effects on growth zone chondrocytes via rapid membrane-associated events as well as through traditional nuclear receptor mechanisms. The membrane-associated signaling pathways include rapid production of diacylglyce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2c03ca63687a4d3b804e4d772e3547
https://pubmed.ncbi.nlm.nih.gov/11455568
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8
Expression and production of stathmin in growth plate chondrocytes is cell-maturation dependent
Autor: T W, Hummert, Z, Schwartz, V L, Sylvia, D D, Dean, R R, Hardin, B D, Boyan
Publikováno v: Journal of cellular biochemistry. 79(1)
Growth plate cartilage is comprised of linear columns of chondrocytes with the least differentiated cells at one end and the terminally differentiated cells at the other end. Rat costochondral chondrocytes can be divided into the resting cell zone (r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41f28a3d1a4cf8a13588100804939f5c
https://pubmed.ncbi.nlm.nih.gov/10906763
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9
24R,25-(OH)(2)D(3) mediates its membrane receptor-dependent effects on protein kinase C and alkaline phosphatase via phospholipase A(2) and cyclooxygenase-1 but not cyclooxygenase-2 in growth plate chondrocytes
Autor: Z, Schwartz, V L, Sylvia, F, Del Toro, R R, Hardin, D D, Dean, B D, Boyan
Publikováno v: Journal of cellular physiology. 182(3)
Recent studies have shown that 24R,25-(OH)(2)D(3) mediates its effects on growth plate chondrocytes via membrane receptors. This study examined the roles of phospholipase A(2) (PLA(2)) and cyclooxygenase (Cox) in the mechanism of action of 24R, 25-(O
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::988c570cf8be3492e6a2c84c714a54a7
https://pubmed.ncbi.nlm.nih.gov/10653606
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10
Failure of DHEA to modulate ovariectomy induced osteopenia in rats
Autor: R. R. Hardin, Richard Cockerham, Dike N. Kalu
Publikováno v: AGE. 6:114-120
As a result of reports indicating that dehydroepiandrosterone (DHEA) has bone anabolic properties, studies were carried out to determine whether DHEA will prevent osteopenia due to ovarian hormone deficiency. Female Sprague Dawley rats were randomize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aedd32f6dc569a1a29ad7a432533a5a8
https://doi.org/10.1007/bf02432199
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