Zobrazeno 1 - 10
of 81
pro vyhledávání: '"R. R. Drake"'
Publikováno v:
Advances in cancer research. 134
In the last decade mass spectrometry imaging has developed rapidly, in terms of multiple new instrumentation innovations, expansion of target molecules, and areas of application. Mass spectrometry imaging has already had a substantial impact in cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd72f8bd61ac138ceefcc7a366d44cbc
https://pubmed.ncbi.nlm.nih.gov/28110655
https://pubmed.ncbi.nlm.nih.gov/28110655
Autor:
A Radominska, R R Drake, S Kyosseva, T M Lutz, Harry Towbin, A D Elbein, C Osborn, Pascal Paul
Publikováno v:
Journal of Biological Chemistry. 268:12933-12938
A new class of compounds designed to inhibit membrane-associated glycosyltransferases were synthesized and their biological activities were characterized in liver microsomes and human lymphoma cell lines. These inhibitors are composed of N-acyl pheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5797373272b35c583c532326ea9fbf71
https://doi.org/10.1016/s0021-9258(18)31475-3
https://doi.org/10.1016/s0021-9258(18)31475-3
Autor:
R R Drake, I van de Rijn
Publikováno v:
Journal of Biological Chemistry. 267:24302-24306
The mucopolysaccharide, hyaluronic acid, is an important component of both mammals and pathogenic streptococci. This high molecular weight polymer is synthesized by a membrane-associated, multisubunit hyaluronate synthase which utilizes UDP-glucuroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6f51398c09e374847e92a896cc9f399
https://doi.org/10.1016/s0021-9258(18)35765-x
https://doi.org/10.1016/s0021-9258(18)35765-x
Publikováno v:
Journal of Biological Chemistry. 265:4782-4784
Photoaffinity labeling of purified cellulose synthase with [beta-32P]5-azidouridine 5'-diphosphoglucose (UDP-Glc) has been used to identify the UDP-Glc binding subunit of the cellulose synthase from Acetobacter xylinum strain ATCC 53582. The results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd0ea85578b80e9009f3bf7d8f9b8d55
https://doi.org/10.1016/s0021-9258(19)34039-6
https://doi.org/10.1016/s0021-9258(19)34039-6
Publikováno v:
The Journal of biological chemistry. 272(22)
A photoaffinity analogue, [beta-32P]5-azido-UDP-GlcA, was used to photolabel the enzymes that utilize UDP-GlcA in cartilage microsomes and rat liver microsomes. SDS-polyacrylamide gel electrophoresis analysis of photolabeled cartilage microsomes, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3e9a68d4962a49e56f42ac8e59f4d46
https://pubmed.ncbi.nlm.nih.gov/9162078
https://pubmed.ncbi.nlm.nih.gov/9162078
Autor:
E, Battaglia, S, Nowell, R R, Drake, J, Magdalou, S, Fournel-Gigleux, C, Senay, A, Radominska
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(4)
Recombinant human liver UDP-glucuronosyltransferase (UGT), UGT1*6, which catalyzes the glucuronidation of small phenols, previously expressed in a V79 cell line (1) was photolabeled with [beta-32P]5N3UDP-glucuronic acid ([beta-32P]5N3UDP-GlcUA). Two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea9d1682d78c0b9fd2b43f8de206c11d
https://pubmed.ncbi.nlm.nih.gov/9107538
https://pubmed.ncbi.nlm.nih.gov/9107538
Publikováno v:
The Journal of biological chemistry. 271(49)
The kinetic properties of UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-phosphotransferase) purified to homogeneity from lactating bovine mammary gland have been investigated. GlcNAc-phosphotransferase tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::159724d65e582fd541cc35a2f3f97ee4
https://pubmed.ncbi.nlm.nih.gov/8940156
https://pubmed.ncbi.nlm.nih.gov/8940156
Autor:
F, Mao, T M, Rechtin, R, Jones, A A, Cantu, L S, Anderson, A, Radominska, M P, Moyer, R R, Drake
Publikováno v:
The Journal of biological chemistry. 270(23)
Long term administration of 3'-azidothymidine (AZT) for the treatment of AIDS has led to detrimental clinical side effects in some patients, the biochemical causes of which are still being delineated. Base-substituted, azido-nucleotide photoaffinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe59fff7e7b0036dc4acdd4a2e3033c3
https://pubmed.ncbi.nlm.nih.gov/7775417
https://pubmed.ncbi.nlm.nih.gov/7775417
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(3)
The photoaffinity analogs [beta-32P]5-azido-UDP-glucuronic acid ([32P]5N3UDP-GlcUA) and [beta-32P]5-azido-UDP-glucose ([32P]5N3UDP-Glc) were used to characterize UDP-glycosyltransferases of microsomes prepared from human liver. Photoincorporation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15a54c8f9a2250ac4a355d75cd38dc3c
https://pubmed.ncbi.nlm.nih.gov/7791131
https://pubmed.ncbi.nlm.nih.gov/7791131
Publikováno v:
European journal of biochemistry. 228(1)
The enzyme, UDPglucuronic acid carboxylase (EC 4.1.1.35), was extensively purified from wheat germ, and was used to convert 5-azido-[32P]UDPglucuronic acid to 5-azido-[32P]UDPxylose, for use as a new photoaffinity probe. The carboxylyase was purified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6493e9090ead8ad989163cce4cf13c9
https://pubmed.ncbi.nlm.nih.gov/7882990
https://pubmed.ncbi.nlm.nih.gov/7882990