Zobrazeno 1 - 10
of 63
pro vyhledávání: '"R. R., Panchuk"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 1, Pp 68-74 (2021)
In this investigation, the level of сortisol in blood plasma and splenocytes apoptosis in male and female rats in response to fear stress created by animals’ waiting for different terms (20, 40, 60 min) before the slaughter were evaluated. A signi
Externí odkaz:
https://doaj.org/article/a692ce206ec74ae8812fab7f6ee8cfb4
Autor:
Yu. S. Kozak, R. R. Panchuk, N. R. Skorokhyd, D. S. Semenovich, A. G. Moiseenok, R. S. Stoika
Publikováno v:
Біологічні студії, Vol 12, Iss 2, Pp 13-24 (2018)
Rapid development of multiple drug resistance and occurrence of negative side effects in cancer patients arising at the treatment belong to the main problems in cancer chemotherapy. Recently, it was shown that specific antioxidants (selenomethionine
Externí odkaz:
https://doaj.org/article/b37c7bba864743fa858c10010aebac87
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 2, Pp 46-54 (2018)
N-acetylcysteine (NAC) is a dietary supplement demonstrating antioxidant and liver protecting effects that is widely used in clinics. NAC is considered to possess potential therapeutic activity for health disorders characterized by generation of free
Externí odkaz:
https://doaj.org/article/0ff15cce1342428982f60aa823e8581b
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 5, Pp 77-83 (2017)
Principal ways of generation and function of free oxygen and nitrogen radical metabolites, as well as the ways of their bio-neutralization in rats treated with potential anticancer drugs have been discussed. Three isatin-pyrazoline 4-thiazolidinone c
Externí odkaz:
https://doaj.org/article/5f3d44cd2b5a4ddc8127d71bb1785d81
Publikováno v:
Біологічні студії, Vol 10, Iss 1, Pp 5-16 (2016)
Landomycin A is a new antibiotic of angucycline group with antineoplastic activity against tumor cells of different origin. In this work, we investigated the effects of landomycin A on the growth of B16F10 mouse melanoma. It was elucidated that studi
Externí odkaz:
https://doaj.org/article/e11e8aab77b14f8cb8b4d268c69d2f34
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 5, Pp 72-82 (2015)
Landomycin A (LA) is a new antitumor antibiotic of angucycline group, possessing high antitumor activity against cancer cells of different origin, which induces early apoptosis in target cells. It was shown that under LA action the level of reactive
Externí odkaz:
https://doaj.org/article/88c4e9c6ee684ed49292c6dd2b31fdbb
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 6, Pp 96-105 (2014)
Pyrazole- and aryl-substituted derivatives of 4-thiazolidinone belong to a perspective group of compounds with potential antitumor action. Earlier, we have demonstrated high toxicity in vitro of several 4-thiazolidinones derivatives towards tumor cel
Externí odkaz:
https://doaj.org/article/762caed23b734102aa1c79dbfcf5bbae
Autor:
V. V. Chumak, R. R. Panchuk, N. O. Manko, D. Ya. Havrylyuk, R. V. Lesyk, L. I. Kobylinska, B. S. Zimenkovsky, R. S. Stoika
Publikováno v:
Біологічні студії, Vol 8, Iss 2, Pp 29-42 (2014)
Compounds on the basis of 4-thiazolidinone and its isatin-containing derivatives are characterized by a broad spectrum of biological activities and are potential antineoplastic agents. We have shown that the combination of 4-thiazolidinone and isatin
Externí odkaz:
https://doaj.org/article/6b94ba341ffa4a289115694e01d4b178
Autor:
R. R. Panchuk, N. R. Skorokhyd, V. V. Chumak, L. V. Lehka, A. G. Moiseenok, W. Berger, R. S. Stoika
Publikováno v:
Біологічні студії, Vol 7, Iss 3, Pp 33-46 (2013)
The aim of this work was to study biological activity of sodium selenite, selenomethionine and D-panthetine towards drug-resistant human leukemia and carcinoma cells, characterized by overexpression of P-glycoprotein and knockout of Bax gene which pl
Externí odkaz:
https://doaj.org/article/55b254d160e445f280471cbbac9fba5e
Autor:
R. R. Panchuk, S. S. Grabovskyi, N. R. Skorokhyd, Rostyslav Stoika, Biotechnologies, Lviv, Ukraine
Publikováno v:
Ukrainian Biochemical Journal, Vol 93, Iss 1, Pp 68-74 (2021)
In this investigation, the level of сortisol in blood plasma and splenocytes apoptosis in male and female rats in response to fear stress created by animals’ waiting for different terms (20, 40, 60 min) before the slaughter were evaluated. A signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3f28f1fc387b9f247bbb63bfd8c3a7
http://ukrbiochemjournal.org/wp-content/uploads/2021/02/Grabovskyi_1_21.pdf
http://ukrbiochemjournal.org/wp-content/uploads/2021/02/Grabovskyi_1_21.pdf