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Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis

Autor: Emma Copland, Dexter Canoy, Milad Nazarzadeh, Zeinab Bidel, Rema Ramakrishnan, Mark Woodward, John Chalmers, Koon K Teo, Carl J Pepine, Barry R Davis, Sverre Kjeldsen, Johan Sundström, Kazem Rahimi, A Adler, L Agodoa, A Algra, F W Asselbergs, N Beckett, E Berge, H Black, F P J Brouwers, M Brown, C J Bulpitt, B Byington, J Chalmers, W C Cushman, J Cutler, B R Davis, R B Devereaux, J Dwyer, R Estacio, R Fagard, K Fox, T Fukui, A K Gupta, R R Holman, Y Imai, M Ishii, S Julius, Y Kanno, S E Kjeldsen, J Kostis, K Kuramoto, J Lanke, E Lewis, J Lewis, M Lievre, L H Lindholm, S Lueders, S MacMahon, G Mancia, M Matsuzaki, M H Mehlum, S Nissen, H Ogawa, T Ogihara, T Ohkubo, C Palmer, A Patel, C J Pepine, M Pfeffer, N R Poulter, H Rakugi, G Reboldi, C Reid, G Remuzzi, P Ruggenenti, T Saruta, J Schrader, R Schrier, P Sever, P Sleight, J A Staessen, H Suzuki, L Thijs, K Ueshima, S Umemoto, W H van Gilst, P Verdecchia, K Wachtell, P Whelton, L Wing, M Woodward, Y Yui, S Yusuf, A Zanchetti, Z Y Zhang, C Anderson, C Baigent, BM Brenner, R Collins, D de Zeeuw, J Lubsen, E Malacco, B Neal, V Perkovic, B Pitt, A Rodgers, P Rothwell, G Salimi-Khorshidi, J Sundström, F Turnbull, G Viberti, J Wang

Findings 33 trials met the inclusion criteria, and included 260 447 participants with 15 012 cancer events. Median follow-up of included participants was 4?2 years (IQR 3?0?5?0). In the individual participant data meta-analysis comparing each drug cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bf241456fba8c60d821c06d95aca03
http://hdl.handle.net/10044/1/89099

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Modelling incremental benefits on complications rates when targeting lower HbA

Autor: S A, Mostafa, R L, Coleman, O F, Agbaje, A M, Gray, R R, Holman, M A, Bethel

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association. 35(1)

Glucose-lowering interventions in Type 2 diabetes mellitus have demonstrated reductions in microvascular complications and modest reductions in macrovascular complications. However, the degree to which targeting different HbAParticipant-level data fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d48534108cdfe60ebb97e2b64d49eacb
https://pubmed.ncbi.nlm.nih.gov/29057545

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The case against aggressive treatment of type 2 diabetes: critique of the UK prospective diabetes study Commentary: UKPDS is well designed and clinically important

Autor: R M Ewart, R. R Holman, D. R Matthews, T. Meade

Publikováno v: BMJ. 323:854-858

The case against aggressive treatment of type 2 diabetes: critique of the UK prospective diabetes study {#article-title-2} #### Summary points During the course of the UK prospective diabetes study the length of follow up was changed, and changes see

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8789205fc70dcb36e3b6d6759b9af8b
https://doi.org/10.1136/bmj.323.7317.854

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Relationship between the severity of retinopathy and progression to photocoagulation in patients with Type 2 diabetes mellitus in the UKPDS (UKPDS 52)

Autor: Uk Prospective Diabetes Study ukpds Group, E. M. Kohner, I. M. Stratton, S. J. Aldington, R. R. Holman, D. R. Matthews

Publikováno v: Diabetic Medicine. 18:178-184

Summary Aim to establish the degree to which the severity of retinopathy determines the risk for the need for subsequent photocoagulation in those with newly diagnosed Type 2 diabetes mellitus. Methods Of 5102 patients entered into the UK Prospective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14705a9f094ac9996d0e64eeae3c5982
https://doi.org/10.1046/j.1464-5491.2001.00458.x

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Participants' experiences of intensifying insulin therapy during the Treating to Target in Type 2 Diabetes (4-T) trial: qualitative interview study

Autor: N, Jenkins, N, Hallowell, A J, Farmer, R R, Holman, J, Lawton

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association. 28(5)

To explore participants' experiences of intensifying insulin therapy during the Treating to Target in Type 2 Diabetes (4-T) trial.In-depth interviews were conducted with 41 trial participants who had had their insulin therapy intensified during this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5de8107ef86fbf2aaeeaa3befae3754c
https://pubmed.ncbi.nlm.nih.gov/21480965

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Blood glucose self-monitoring in type 2 diabetes: A randomised controlled trial

Autor: A J, Farmer, A N, Wade, D P, French, J, Simon, P, Yudkin, A, Gray, A, Craven, L, Goyder, R R, Holman, D, Mant, A-L, Kinmonth, H A W, Neil, K, Islam

Publikováno v: Health Technology Assessment, Vol 13, Iss 15 (2009)

OBJECTIVES: To determine whether self-monitoring of blood glucose (SMBG), either alone or with additional instruction in incorporating the results into self-care, is more effective than usual care in improving glycaemic control in non-insulin-treated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04e74264e2f8d9182bcd4ad2e7c736f
http://ora.ox.ac.uk/objects/uuid:46554ad7-2462-4477-9768-fa86c9188306

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Relationship between ethnicity and glycemic control, lipid profiles, and blood pressure during the first 9 years of type 2 diabetes: U.K. Prospective Diabetes Study (UKPDS 55)

Autor: T M, Davis, C A, Cull, R R, Holman

Publikováno v: Diabetes care. 24(7)

To assess the relationship among self-reported ethnicity, metabolic control, and blood pressure during treatment of type 2 diabetes.We studied 2,999 newly diagnosed type 2 diabetic patients recruited to the U.K. Prospective Diabetes Study who were ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d439ee40cc6e1d1ec6adc1a6db4fef2
https://pubmed.ncbi.nlm.nih.gov/11423497

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Relationship between the severity of retinopathy and progression to photocoagulation in patients with Type 2 diabetes mellitus in the UKPDS (UKPDS 52)

Autor: E M, Kohner, I M, Stratton, S J, Aldington, R R, Holman, D R, Matthews

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association. 18(3)

to establish the degree to which the severity of retinopathy determines the risk for the need for subsequent photocoagulation in those with newly diagnosed Type 2 diabetes mellitus.Of 5102 patients entered into the UK Prospective Diabetes Study (UKPD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::121b9661735c9b435659f698fb343505
https://pubmed.ncbi.nlm.nih.gov/11318837

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