HLA association in MOG-IgG- and AQP4-IgG-related disorders of the CNS in the Dutch population

Autor: Arlette L. Bruijstens, Yu Yi M. Wong, Beatrijs H.A. Wokke, Pieter J.E. van der Linden, Daniëlle E. van Pelt, Frans H.J. Claas, Rinze F. Neuteboom, Geert W. Haasnoot, R Q Hintzen

Publikováno v: Neurology(R) neuroimmunology & neuroinflammation, 7. Lippincott Williams & Wilkins
Neurology® Neuroimmunology & Neuroinflammation

ObjectiveTo investigate the possible human leukocyte antigen (HLA) association of both myelin oligodendrocyte glycoprotein (MOG-IgG)-associated diseases (MOGAD) and aquaporin-4 antibody (AQP4-IgG)-positive neuromyelitis optica spectrum disorders (NMO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18263a62e3b320b282f5ff9ed88983fc
https://pure.eur.nl/en/publications/81a3e510-20d4-4a69-89c4-513a329e180a

Fatigue and physical functioning in children with multiple sclerosis and acute disseminated encephalomyelitis

Autor: R Q Hintzen, Coriene E. Catsman-Berrevoets, Rinze F. Neuteboom, Monique H M van der Cammen-van Zijp, Yu Yi M Wong, Daniëlle Van Pelt-Gravesteijn, Leontien C C Toussaint-Duyster

Publikováno v: Multiple Sclerosis (Houndmills, Basingstoke, England)
Multiple Sclerosis, 24(7), 982-990. SAGE Publications Ltd

Background and Objective: Fatigue and physical impairments are a major concern in children with multiple sclerosis (MS) and after acute disseminated encephalomyelitis (post-ADEM). We here aimed to evaluate the interaction between fatigue, exercise ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec3067fad10d9a2696efc959d23ab34
https://doi.org/10.1177/1352458517706038

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

Autor: Seema Kalra, Graeme J. Stewart, Katrina Dedham, Tfm Andlauer, Frauke Zipp, X Jia, Adam Santaniello, Bertrand Fontaine, Stacy J Caillier, Giancarlo Comi, Hanne F. Harbo, Ashley Beecham, Lisa F. Barcellos, Jacob L. McCauley, Aarno Palotie, P. L. De Jager, Ji Kira, Noriko Isobe, B. Hemmer, Lincoln, Farren B.S. Briggs, Christina M. Lill, Sergio E. Baranzini, Booth, F. Martinelli-Boneschi, A. Oturai, Pierre Duquette, Janna Saarela, A Compston, Roland G. Henry, D Efthimios, Chris Cotsapas, Jonathan L. Haines, Clive Hawkins, Federica Esposito, David A. Hafler, Giorgos M. Hadjigeorgiou, Elisabeth Gulowsen Celius, Stephen Sawcer, Lohith Madireddy, Oksenberg, Christiane Gasperi, Bac Cree, Luisa Bernardinelli, Felix Luessi, A Ivinson, Nikolaos A. Patsopoulos, Steffan D. Bos, Tomas Olsson, Bénédicte Dubois, Ingrid Kockum, Dana Horakova, Margaret A. Pericak-Vance, R Q Hintzen, An Goris, Sandra D'Alfonso, Tone Berge, Michael Khalil, Stephen L. Hauser, Bruce V. Taylor, Kicheol Kim, Roland Martin, Pierre-Antoine Gourraud, Manuel Comabella

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
International Multiple Sclerosis Genetics Consortium,. (2019). A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis.. Nature communications, 10(1), 2236. doi: 10.1038/s41467-019-09773-y. UCSF: Retrieved from: http://www.escholarship.org/uc/item/5f91v8cb
Nature communications, vol 10, iss 1
Nature Communications, 10:2236. Nature Publishing Group
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
International Multiple Sclerosis Genetics Consortium 2019, ' A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis ', Nature Communications, vol. 10, no. 1, 2236 . https://doi.org/10.1038/s41467-019-09773-y

Genome-wide association studies (GWAS) have identified more than 50,000 unique associations with common human traits. While this represents a substantial step forward, establishing the biology underlying these associations has proven extremely diffic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88add5147a1355a065934ccb0127aabe
https://lirias.kuleuven.be/handle/123456789/643793

Pediatric acquired CNS demyelinating syndromes Features associated with multiple sclerosis

Autor: Brenda Banwell, Russell C. Dale, Rinze F. Neuteboom, Soe Mar, R Q Hintzen

Publikováno v: Neurology, 87(9), S67-S73. Lippincott Williams & Wilkins

Approximately one-third of children with an acquired demyelinating syndrome (ADS) will be diagnosed with multiple sclerosis (MS), either at onset according to the 2010 McDonald criteria, or on the basis of clinical or MRI evidence of relapsing diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126bc33007f6041b7638e3ec3ebcc03b
https://doi.org/10.1212/wnl.0000000000002881

Validation of MRI predictors of multiple sclerosis diagnosis in children with acute CNS demyelination

Autor: Rinze F. Neuteboom, E. van Pelt-Gravesteijn, Immy A. Ketelslegers, David L. Streiner, Coriene E. Catsman-Berrevoets, Brian M. Feldman, R Q Hintzen, Leonard H. Verhey, Brenda Banwell, John G. Sled

Publikováno v: Multiple Sclerosis and Related Disorders. 2:193-199

Background In a recent Canadian prospective study of children with acute demyelinating syndromes (ADS), we demonstrated that the presence of T2 periventricular and T1-hypointense lesions predicted MS diagnosis. We aimed to validate these predictors i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e746bb3230f54416d2d8d34c0310a2e1
https://doi.org/10.1016/j.msard.2012.12.003