Zobrazeno 1 - 10
of 209
pro vyhledávání: '"R. Preston Mason"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background Endothelial cell (EC) dysfunction involves reduced nitric oxide (NO) bioavailability due to NO synthase uncoupling linked to increased oxidation and reduced cofactor availability. Loss of endothelial function and NO bioavailability are ass
Externí odkaz:
https://doaj.org/article/79df8e5fb2eb4e8db8625da68cb4e4ce
Autor:
Samuel C.R. Sherratt, Peter Libby, Hazem Dawoud, Deepak L. Bhatt, Tadeusz Malinski, R. Preston Mason
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114629- (2023)
Aims: Inhalation of air pollution small particle matter (PM) is a leading cause of cardiovascular (CV) disease. Exposure to PMs causes endothelial cell (EC) dysfunction as evidenced by nitric oxide (NO) synthase uncoupling, vasoconstriction and infla
Externí odkaz:
https://doaj.org/article/24031662b6d14eeead7efd230a03d49a
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/dfcd073df3a14101b440a7c13fba49b1
Autor:
Andrew Kosmopoulos, Deepak L. Bhatt, Gus Meglis, Raj Verma, Yi Pan, Adrian Quan, Hwee Teoh, Maya Verma, Lixia Jiao, Robert Wang, Rebecca A. Juliano, Mahesh Kajil, Mikhail N. Kosiborod, Basel Bari, Abdullahi A. Berih, Mallory Aguilar, Antonnette Escano, Andrew Leung, Idelta Coelho, Makoto Hibino, Rafael Díaz, R. Preston Mason, Ph. Gabriel Steg, Tabassome Simon, Alan S. Go, Andrew P. Ambrosy, Richard Choi, Arthur M. Kushner, Lawrence A. Leiter, Mohammed Al-Omran, Subodh Verma, C. David Mazer
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103040- (2021)
Summary: The coronavirus disease 2019 (COVID-19) pandemic remains a source of considerable morbidity and mortality throughout the world. Therapeutic options to reduce symptoms, inflammatory response, or disease progression are limited. This randomize
Externí odkaz:
https://doaj.org/article/26ff798370704467a00107bd76266791
Autor:
Samuel C.R. Sherratt, Rebecca A. Juliano, Christina Copland, Deepak L. Bhatt, Peter Libby, R. Preston Mason
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100106- (2021)
Omega-3 FAs EPA and DHA influence membrane fluidity, lipid rafts, and signal transduction. A clinical trial, Reduction of Cardiovascular Events with Icosapent Ethyl—Intervention Trial, demonstrated that high-dose EPA (4 g/d icosapent ethyl) reduced
Externí odkaz:
https://doaj.org/article/ed2f7c180e724ec48de4021a49614ae7
Autor:
Thomas N. Tulenko, Kathy Boeze-Battaglia, R. Preston Mason, G. Stephen Tint, Robert D. Steiner, William E. Connor, Edward F. Labelle
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 134-143 (2006)
The Smith-Lemli-Opitz syndrome (SLOS) is an often lethal birth defect resulting from mutations in the gene responsible for the synthesis of the enzyme 3β-hydroxy-steroid-Δ7-reductase, which catalyzes the reduction of the double bond at carbon 7 on
Externí odkaz:
https://doaj.org/article/c28f947ab933436e8df292ea5241847b
Autor:
Richard J. Cenedella, Robert Jacob, Douglas Borchman, Daxin Tang, Amanda R. Neely, Abbas Samadi, R. Preston Mason, Patricia Sexton
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 7, Pp 1232-1241 (2004)
Induction of cataracts in experimental animals is a common toxic feature of oxidosqualene cyclase (OSC) inhibitors. U18666A has been shown to produce irreversible lens damage within a few weeks of treatment. Drug actions, besides reducing the availab
Externí odkaz:
https://doaj.org/article/c857a1a0d008499e83b021508b140f05
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 5, Pp 947-956 (1998)
Small angle X-ray diffraction was used to examine arterial smooth muscle cell (SMC) plasma membranes isolated from control and cholesterol-fed (2%) atherosclerotic rabbits. A microsomal membrane enriched with plasma membrane obtained from animals fed
Externí odkaz:
https://doaj.org/article/84d7c234e21e43c7be287c7fc329bd71
Autor:
Vidit V. Satokar, José G.B. Derraik, Matire Harwood, Karaponi Okesene-Gafa, Kathryn Beck, David Cameron-Smith, Manohar L. Garg, Justin M. O’Sullivan, Gerhard Sundborn, Shikha Pundir, R Preston Mason, Wayne S. Cutfield, Benjamin B. Albert
Publikováno v:
The American Journal of Clinical Nutrition. 117:883-895
Autor:
Paul M Ridker, Nader Rifai, Jean MacFadyen, Robert J. Glynn, Lixia Jiao, Ph. Gabriel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Jean-Claude Tardif, Christie M. Ballantyne, R. Preston Mason, Deepak L. Bhatt
Publikováno v:
Circulation. 146:372-379
Background: REDUCE-IT (Reduction of Cardiovascular Events With Icosapent Ethyl—Intervention Trial) reported a 25% relative risk reduction in major adverse cardiovascular events with use of icosapent ethyl compared with pharmaceutical grade mineral