Zobrazeno 1 - 10
of 138
pro vyhledávání: '"R. Portman"'
Autor:
O. Menard, U. Lesmes, C. S. Shani-Levi, A. Araiza Calahorra, A. Lavoisier, M. Morzel, A. Rieder, G. Feron, S. Nebbia, L. Mashiah, A. Andres, G. Bornhorst, F. Carrière, L. Egger, S. Gwala, A. Heredia, B. Kirkhus, A. Macierzanka, R. Portman, I. Recio, V. Santé-Lhoutellier, C. Tournier, A. Sarkar, A. Brodkorb, A. Mackie, D. Dupont
Publikováno v:
Food and Function
Food and Function, 2023, 14 (10), pp.4569-4582. ⟨10.1039/D3FO00535F⟩
Food and Function, 2023, 14 (10), pp.4569-4582. ⟨10.1039/D3FO00535F⟩
This article is part of the themed collection: Food & Function HOT Articles 2023.; International audience; Understanding the mechanisms of food digestion is of paramount importance to determine the effect foods have on human health. Significant knowl
Autor:
A.-M. Reiche, M.C. Martín-Hernández, A. Spengler Neff, B. Bapst, C. Fleuti, F. Dohme-Meier, H.D. Hess, L. Egger, R. Portmann
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 9, Pp 6425-6436 (2024)
ABSTRACT: The effect of the horn status of cows on their milk composition and quality is a controversial research topic. In this study, 128 milk samples from 64 horned and 64 disbudded Brown Swiss and Original Braunvieh cows were collected from alpin
Externí odkaz:
https://doaj.org/article/464124ed86ec47e0b732d42f79c95b98
Autor:
Roland H Stimson, Neil Henderson, Marc R. Dweck, Cécile Bénézech, Zoi Michalidou, Calum C. Bain, Stephen J. Jenkins, Prakash Ramachandran, Laura Denby, Lucy H. Jackson-Jones, Marlene Magalhaes, Jordan R. Portman, Pete Smith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Magalhaes, M S, Smith, P, Portman, J, Jackson-Jones, L H, Bain, C C, Ramachandran, P, Michailidou, Z, Stimson, R H, Dweck, M R, Denby, L, Henderson, N C, Jenkins, S J & Benezech, C 2021, ' Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels ', Nature Communications . https://doi.org/10.1038/s41467-021-24684-7
Nature Communications
Magalhaes, M S, Smith, P, Portman, J, Jackson-Jones, L H, Bain, C C, Ramachandran, P, Michailidou, Z, Stimson, R H, Dweck, M R, Denby, L, Henderson, N C, Jenkins, S J & Benezech, C 2021, ' Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels ', Nature Communications . https://doi.org/10.1038/s41467-021-24684-7
Dyslipidemia is a main driver of cardiovascular diseases. The ability of macrophages to scavenge excess lipids implicate them as mediators in this process and understanding the mechanisms underlying macrophage lipid metabolism is key to the developme
Publikováno v:
Nucleic acids research. 50(13)
Stalling of the transcription elongation complex formed by DNA, RNA polymerase (RNAP) and RNA presents a serious obstacle to concurrent processes due to the extremely high stability of the DNA-bound polymerase. RapA, known to remove RNAP from DNA in
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 24, Pp 2541-2558 (2024)
Hail represents a major threat to agriculture in Switzerland, and assessments of current and future hail risk are of paramount importance for decision-making in the insurance industry and the agricultural sector. However, relating observational infor
Externí odkaz:
https://doaj.org/article/b86009488f0f4f23add16cceadea1bdb
Autor:
M. S. Magalhaes, P. Smith, J. R. Portman, L. H. Jackson-Jones, C. C. Bain, P. Ramachandran, Z. Michailidou, R. H. Stimson, M. R. Dweck, L. Denby, N. C. Henderson, S. J. Jenkins, C. Bénézech
Publikováno v:
Nature Communications. 13
Autor:
S. J. De Hertog, C. E. Lopez-Fabara, R. van der Ent, J. Keune, D. G. Miralles, R. Portmann, S. Schemm, F. Havermann, S. Guo, F. Luo, I. Manola, Q. Lejeune, J. Pongratz, C.-F. Schleussner, S. I. Seneviratne, W. Thiery
Publikováno v:
Earth System Dynamics, Vol 15, Pp 265-291 (2024)
Land cover and land management changes (LCLMCs) play an important role in achieving low-end warming scenarios through land-based mitigation. However, their effects on moisture fluxes and recycling remain uncertain, although they have important implic
Externí odkaz:
https://doaj.org/article/425b6b1936ae4acd86eae02c2934121d
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 24, Pp 847-872 (2024)
Severe hailstorms result in substantial damage to buildings and vehicles, necessitating the quantification of associated risks. Here, we present a novel open-source hail damage model for buildings and cars based on single-polarization radar data and
Externí odkaz:
https://doaj.org/article/5c1da654a4e5497c8e5da2b91af0ba77
Autor:
Mirjana Efremova, Ross Dobie, Jonathan A. Fallowfield, Prakash Ramachandran, Stephen J. Wigmore, John P. Iredale, Ewen M Harrison, Kylie P. Matchett, John C. Marioni, David R. Mole, Christopher J. Weston, John A. Marwick, John R. Wilson-Kanamori, Roser Vento-Tormo, Philip N. Newsome, Sarah A. Teichmann, Neil C. Henderson, Neil O. Carragher, Richard S Taylor, Jordan R. Portman, Elena Dora, N T Luu, Frank Tacke, Chris P. Ponting, Jeffrey W. Pollard, Beth E. P. Henderson, Timothy J. Kendall, M Brice
Publikováno v:
Nature
Ramachandran, P, Dobie, R, Wilson-Kanamori, J R, Dora, E F, Henderson, B E P, Luu, N T, Portman, J R, Matchett, K P, Brice, M, Marwick, J A, Taylor, R S, Efremova, M, Vento-Tormo, R, Carragher, N O, Kendall, T J, Fallowfield, J A, Harrison, E M, Mole, D J, Wigmore, S J, Newsome, P N, Weston, C J, Iredale, J P, Tacke, F, Pollard, J W, Ponting, C P, Marioni, J C, Teichmann, S A & Henderson, N C 2019, ' Resolving the fibrotic niche of human liver cirrhosis at single-cell level ', Nature, vol. 575, no. 7783, pp. 512–518 . https://doi.org/10.1038/s41586-019-1631-3
Ramachandran, P, Dobie, R, Wilson-Kanamori, J R, Dora, E F, Henderson, B E P, Luu, N T, Portman, J R, Matchett, K P, Brice, M, Marwick, J A, Taylor, R S, Efremova, M, Vento-Tormo, R, Carragher, N O, Kendall, T J, Fallowfield, J A, Harrison, E M, Mole, D J, Wigmore, S J, Newsome, P N, Weston, C J, Iredale, J P, Tacke, F, Pollard, J W, Ponting, C P, Marioni, J C, Teichmann, S A & Henderson, N C 2019, ' Resolving the fibrotic niche of human liver cirrhosis at single-cell level ', Nature, vol. 575, no. 7783, pp. 512–518 . https://doi.org/10.1038/s41586-019-1631-3
Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available. To obtain a better understanding of the cellular and molecular mechanisms involved in d
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Portman, J R, Brouwer, G M, Bollins, J M, Savery, N J & Strick, T R 2021, ' Cotranscriptional R-loop formation by Mfd involves topological partitioning of DNA ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 15, e2019630118 . https://doi.org/10.1073/pnas.2019630118
Portman, J R, Brouwer, G M, Bollins, J M, Savery, N J & Strick, T R 2021, ' Cotranscriptional R-loop formation by Mfd involves topological partitioning of DNA ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 15, e2019630118 . https://doi.org/10.1073/pnas.2019630118
Significance R-loop structures pose a threat to genomic integrity because their formation can lead to mutagenesis. Mutagenesis drives antibiotic resistance in bacteria and chemotherapy resistance in human cancers; therefore, it is important to unders