Zobrazeno 1 - 10
of 99
pro vyhledávání: '"R. Pettipher"'
Publikováno v:
Clinical and Experimental Immunology. 156:126-133
SummaryThe mechanisms by which immunologically activated mast cells stimulate the production of proinflammatory cytokines by T helper type 2 (Th2) lymphocytes were investigated in a human cell culture system. Supernatants collected from cord blood-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b85390c7104842c3a3e049643cad00e
https://doi.org/10.1111/j.1365-2249.2008.03871.x
https://doi.org/10.1111/j.1365-2249.2008.03871.x
Autor:
R Pettipher
Publikováno v:
British Journal of Pharmacology. 153:S191-S199
Prostaglandin D(2) (PGD(2)) is produced by mast cells, Th2 lymphocytes and dendritic cells and has been detected in high concentrations at sites of allergic inflammation. PGD(2) exerts its inflammatory effects through high affinity interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e7a6b58d852310fe5066cf8bef55cbd
https://doi.org/10.1038/sj.bjp.0707488
https://doi.org/10.1038/sj.bjp.0707488
Autor:
M. Buckley, R. Pettipher, V. Chance, Thomas T. MacDonald, Sylvia L.F. Pender, M. Edwards, C.V. Whiting
Publikováno v:
Gut. 54:1114-1120
Exacerbations of inflammatory bowel disease are thought to be related to concurrent infections. As infections are associated with elevated local and serum concentrations of chemokines, we have determined whether systemic administration of the CC chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ef5e355d230af3c423f06e200d75b4
https://doi.org/10.1136/gut.2004.052779
https://doi.org/10.1136/gut.2004.052779
Publikováno v:
The Journal of Immunology. 159:383-390
The effect of nitric oxide synthase (NOS) inhibitors on plasma extravasation in a rat model of zymosan-induced inflammation has been investigated. Plasma extravasation was determined in response to intradermal test agents over 0 to 45 min or 0 to 4 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98a5d2f2b51d4f422c9803b33d97e9a
https://doi.org/10.4049/jimmunol.159.1.383
https://doi.org/10.4049/jimmunol.159.1.383
Publikováno v:
British Journal of Pharmacology. 117:1530-1534
1. The role of adrenal hormones in the regulation of the systemic and local production of tumour necrosis factor (TNF alpha) was examined in male Balb/c mice. 2. Intraperitoneal injection of 0.3 mg E. coli lipopolysaccharide (LPS, 0111:B4) led to hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95023562be0c8b51593d3d58dfa661e
https://doi.org/10.1111/j.1476-5381.1996.tb15317.x
https://doi.org/10.1111/j.1476-5381.1996.tb15317.x
Autor:
Ronald P. Gladue, Henry J. Showell, D. N. Scampoli, E. D. Salter, E. R. Pettipher, L A Carroll, L Contillo, A J Milici, Hans Stukenbrok
Publikováno v:
The Journal of Experimental Medicine
Leukotriene B4 (LTB4) is a chemotactic and cell-activating factor present at inflammatory sites in a variety of autoimmune diseases including multiple sclerosis (MS). In this study, we used a murine model of MS, experimental allergic encephalomyeliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6606a22daa05a4bc9456afd176f38a3d
http://europepmc.org/articles/PMC2192487
http://europepmc.org/articles/PMC2192487
Autor:
N, Barnes, I, Pavord, A, Chuchalin, J, Bell, M, Hunter, T, Lewis, D, Parker, M, Payton, L Pearce, Collins, R, Pettipher, J, Steiner, C M, Perkins
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 42(1)
CRTH2 is a G-protein-coupled receptor that mediates the activation of Th2 lymphocytes, eosinophils and basophils in response to prostaglandin D(2) and may be involved in the pathogenesis of airway inflammation and dysfunction in asthma.To evaluate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad9040e26f6bcd242e68f51d1e4ed59e
https://pubmed.ncbi.nlm.nih.gov/21762224
https://pubmed.ncbi.nlm.nih.gov/21762224
Autor:
E. R. Pettipher, Allen J. Duplantier, K. L. Johnson, Kenneth G. Kraus, R. J. Chambers, T. A. Hibbs, John B. Cheng, Anthony Marfat, E. D. Salter, John P. Umland, T. H. Jenkinson, J.T. Shirley, V. L. Cohan, David B. Damon
Publikováno v:
ChemInform. 28
Tumor necrosis factor-α (TNF-α) has been implicated as a key mediator in the progression of rheumatoid arthritis. Inhibitors of phosphodiesterase IV (PDE IV) have been shown to inhibit the production of TNF-α by elevating intracellular levels of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8b4411bdb87585bc5d357137963c635
https://doi.org/10.1002/chin.199729128
https://doi.org/10.1002/chin.199729128
Publikováno v:
Arthritis & Rheumatism. 33:241-246
Chronic monarticular arthritis can be induced in ovalbumin-sensitized rabbits by intraarticular injection of ovalbumin (antigen-induced arthritis) or in naive rabbits by injecting hyaluronic acid mixed with the polycation poly-D-lysine (polycation-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca6e9c5783df712cd3627323497afe3
https://doi.org/10.1002/art.1780330213
https://doi.org/10.1002/art.1780330213
Autor:
R, Pettipher
Publikováno v:
British journal of pharmacology. 153
Prostaglandin D(2) (PGD(2)) is produced by mast cells, Th2 lymphocytes and dendritic cells and has been detected in high concentrations at sites of allergic inflammation. PGD(2) exerts its inflammatory effects through high affinity interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e928f3de9d7d29e436f515fe84894c40
https://pubmed.ncbi.nlm.nih.gov/17965752
https://pubmed.ncbi.nlm.nih.gov/17965752