Zobrazeno 1 - 10
of 119
pro vyhledávání: '"R. Parham"'
Autor:
Alena Klochkova, Adam L. Karami, Annie D. Fuller, Louis R. Parham, Surali R. Panchani, Shruthi Natarajan, Jazmyne L. Jackson, Anbin Mu, Yinfei Tan, Kathy Q. Cai, Andres J. Klein-Szanto, Amanda B. Muir, Marie-Pier Tétreault, Xavier Graña, Kathryn E. Hamilton, Kelly A. Whelan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 15-40 (2024)
Background & Aims: Autophagy plays roles in esophageal pathologies both benign and malignant. Here, we aim to define the role of autophagy in esophageal epithelial homeostasis. Methods: We generated tamoxifen-inducible, squamous epithelial-specific A
Externí odkaz:
https://doaj.org/article/10798208ac324620b1299c8ac2877db4
Autor:
Louis R. Parham, Patrick A. Williams, Kay Katada, Shaneice K. Nettleford, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 439-451 (2024)
Background & Aims: The intestinal epithelium interfaces with a diverse milieu of luminal contents while maintaining robust digestive and barrier functions. Facultative intestinal stem cells are cells that survive tissue injury and divide to re-establ
Externí odkaz:
https://doaj.org/article/2d55833f363e489b8c29b533990b04ea
Autor:
Reny B. Tyson Moore, Kim W. Urian, Jason B. Allen, Carolyn Cush, Jason R. Parham, Drew Blount, Jason Holmberg, Jamie W. Thompson, Randall S. Wells
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/8432fb2f1b584876824ddd1961b93236
Autor:
Reny B. Tyson Moore, Kim W. Urian, Jason B. Allen, Carolyn Cush, Jason R. Parham, Drew Blount, Jason Holmberg, Jamie W. Thompson, Randall S. Wells
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
Photographic-identification (photo-ID) of bottlenose dolphins using individually distinctive features on the dorsal fin is a well-established and useful tool for tracking individuals; however, this method can be labor-intensive, especially when deali
Externí odkaz:
https://doaj.org/article/d94a975edbfb4921a664d932a5e9bc39
Autor:
Patrick A. Williams, Kaitlyn E. Naughton, Lauren A. Simon, Gloria E. Soto, Louis R. Parham, Xianghui Ma, Charles H. Danan, Weiming Hu, Elliot S. Friedman, Emily A. McMillan, Hritik Mehta, Madison A. Stoltz, Joshua Soto Ocaña, Joseph P. Zackular, Kyle Bittinger, Kelly A. Whelan, Tatiana A. Karakasheva, Kathryn E. Hamilton
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G354-G368
Calorie restriction is associated with enhanced intestinal regeneration after irradiation, but the requirement of autophagy for this process is not known. Our data support the premise that intestinal epithelial autophagy is required for the regenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44fc3763373a94ce9dc3378294b45837
https://doi.org/10.1152/ajpgi.00248.2022
https://doi.org/10.1152/ajpgi.00248.2022
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G91-G98
The profound complexity of the intestinal mucosa demands a spatial approach to the study of gut transcriptomics. Although single-cell RNA sequencing has revolutionized our ability to survey the diverse cell types of the intestine, knowledge of cell t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c2c3c24b99e19b4833d530705cd49d
https://doi.org/10.1152/ajpgi.00191.2022
https://doi.org/10.1152/ajpgi.00191.2022
Autor:
Madeline Kuhn, Yang Zhang, John Favate, Mayu Morita, Aurora Blucher, Sukanya Das, Shun Liang, Ranjan Preet, Louis R. Parham, Kathy N. Williams, Sudheer Molugu, Randall J. Armstrong, Wei Zhang, Jiegang Yang, Kathryn E. Hamilton, Dan A. Dixon, Gordon Mills, Terry K. Morgan, Premal Shah, Sarah F. Andres
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 323:G571-G585
Colorectal cancer (CRC) is a leading cause of cancer-related death. There is an urgent need for new methods of early CRC detection and monitoring to improve patient outcomes. Extracellular vesicles (EVs) are secreted, lipid-bilayer bound, nanoparticl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f2b5fa3451e20c848f6159fb2ef68b
https://doi.org/10.1152/ajpgi.00121.2022
https://doi.org/10.1152/ajpgi.00121.2022
Autor:
Charles H. Danan, Kaitlyn E. Naughton, Katharina E. Hayer, Sangeevan Vellappan, Emily A. McMillan, Yusen Zhou, Rina Matsuda, Shaneice K. Nettleford, Kay Katada, Louis R. Parham, Xianghui Ma, Afrah Chowdhury, Benjamin J. Wilkins, Premal Shah, Matthew D. Weitzman, Kathryn E. Hamilton
Intestinal epithelial transit amplifying cells are essential stem progenitors required for intestinal homeostasis, but their rapid proliferation renders them vulnerable to DNA damage from radiation and chemotherapy. Despite their critical roles in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ba4e1d29349598369deb0938fa2c80
https://doi.org/10.1101/2023.04.06.535853
https://doi.org/10.1101/2023.04.06.535853
Understanding how macroautophagy/autophagy contributes to tissue homeostasis is essential for understanding organismal health. The intestinal epithelium is an ideal model to define mechanisms that regulate tissue homeostasis because it houses well-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae245c003ed16850375fe6ef989fc91
Autor:
Jacinta M. Gau, Jonathan R. Parham
Publikováno v:
Justice and Legitimacy in Policing ISBN: 9781003285267
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e30d0b28cb7c7fd26a339ecd266e951
https://doi.org/10.4324/9781003285267-3
https://doi.org/10.4324/9781003285267-3