Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R. P. Yasuda"'
Autor:
M. Li, S. J. Wall, Indu S. Ambudkar, Bruce J. Baum, Chih Ko Yeh, Yanshan Dai, Eleni E. Kousvelari, B. B. Wolfe, Valerie J. Horn, R. P. Yasuda
Publikováno v:
American Journal of Physiology-Cell Physiology. 261:C1063-C1073
The binding affinities of muscarinic antagonists were compared with their abilities to block carbachol (CCh)-mediated stimulation of Ca2+ mobilization and inhibition of isoproterenol-elicited adenosine 3',5'-cyclic monophosphate (cAMP) accumulation i
Publikováno v:
Journal of neurochemistry. 79(2)
Neuronal nicotinic acetylcholine receptors (nAChRs) play a significant role in sympathetic transmission in the superior cervical ganglia (SCG), with most of the signal carried by a nAChR containing an alpha3 subunit. Work has shown that transection o
Autor:
M, Ferreira, S N, Ebert, D C, Perry, R P, Yasuda, C M, Baker, M I, Dávila-García, K J, Kellar, R A, Gillis
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(2)
In vitro autoradiography using 125I-alpha-bungarotoxin (alpha-BGTx) and anti-alpha7 immunohistochemistry were performed on the dorsal motor nucleus of the vagus (DMV) of sham and chronically vagotomized rats to determine whether the alpha7-nicotinic
Publikováno v:
Molecular pharmacology. 57(2)
Recent evidence has linked striatal N-methyl-D-aspartate (NMDA) receptor function to the adverse effects of long-term dopaminergic treatment in Parkinson's disease. We have studied the abundance, composition, and phosphorylation of NMDA receptor subu
Autor:
R P, Yasuda, W, Ciesla, L R, Flores, S J, Wall, M, Li, S A, Satkus, J S, Weisstein, B V, Spagnola, B B, Wolfe
Publikováno v:
Molecular pharmacology. 43(2)
A portion of the cDNA sequence corresponding to the third intracellular loop of either the m4 or m5 muscarinic cholinergic receptor was ligated into the pRIT23 or pET-3a expression vector, respectively. The expressed fusion proteins were purified and
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
The regulation of individual muscarinic receptor subtypes in rat cerebral cortex/dorsal hippocampus was examined following 14-day administration of the nonselective antagonist atropine. Total muscarinic receptor density increased 24%, from 2196 fmol/
Publikováno v:
Molecular pharmacology. 40(5)
A synthetic oligopeptide (QCDKRKRRKQQYQQRQSV) corresponding to a carboxyl-terminal sequence of the rat m3 receptor (amino acids 561-578) was coupled to carrier proteins and used to generate a polyclonal antiserum. This serum selectively immunoprecipi
Publikováno v:
Molecular pharmacology. 40(1)
The DNA fragment encoding the third intracellular loop of rat m2 muscarinic receptor was fused to the gene for staphylococcal Protein A. The resultant fusion protein, expressed in bacteria, was purified via IgG affinity chromatography and used as an
Publikováno v:
Molecular pharmacology. 39(5)
A fragment of the cDNA encoding the third intracellular loop of the rat m1 muscarinic receptor was cloned, and the DNA was expressed in Escherichia coli as a fusion protein. The fusion protein was purified and utilized as an antigen to raise a polycl
Autor:
J, Peris, S J, Boyson, W A, Cass, P, Curella, L P, Dwoskin, G, Larson, L H, Lin, R P, Yasuda, N R, Zahniser
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 253(1)
The purpose of this study was to test whether persistent changes consistent with behavioral sensitization occur in dopamine (DA) uptake, release or receptors following repeated cocaine administration. Our neurochemical experiments focused primarily o