Zobrazeno 1 - 10
of 163
pro vyhledávání: '"R. P. Wright"'
Autor:
Patarasuda Chaisupa, R. Clay Wright
Publikováno v:
SLAS Technology, Vol 29, Iss 2, Pp 100113- (2024)
Genetically encoded biosensors are crucial for enhancing our understanding of how molecules regulate biological systems. Small molecule biosensors, in particular, help us understand the interaction between chemicals and biological processes. They als
Externí odkaz:
https://doaj.org/article/1d64299bc97b4feea1cbb2426a01dfb2
Autor:
John A. Bryant, Jr, Cameron Longmire, Sriya Sridhar, Samuel Janousek, Mason Kellinger, R. Clay Wright
Publikováno v:
SLAS Technology, Vol 29, Iss 2, Pp 100107- (2024)
Every year biotechnology labs generate a combined total of ∼5.5 million tons of plastic waste. As the global bioeconomy expands, biofoundries will inevitably increase plastic consumption in-step with synthetic biology scaling. Decontamination and r
Externí odkaz:
https://doaj.org/article/6a0959271890464db67b3fb0ae87d23e
Autor:
Jonathon W. Senefeld, PhD, Ellen K. Gorman, BS, Patrick W. Johnson, BS, M. Erin Moir, PhD, Stephen A. Klassen, PhD, Rickey E. Carter, PhD, Nigel S. Paneth, MD, David J. Sullivan, MD, Olaf H. Morkeberg, BA, R. Scott Wright, MD, DeLisa Fairweather, PhD, Katelyn A. Bruno, PhD, Shmuel Shoham, MD, Evan M. Bloch, MBChB, MS, Daniele Focosi, MD, Jeffrey P. Henderson, MD, PhD, Justin E. Juskewitch, MD, PhD, Liise-Anne Pirofski, MD, Brenda J. Grossman, MD, MPH, Aaron A.R. Tobian, MD, PhD, Massimo Franchini, MD, Ravindra Ganesh, MBBS, MD, Ryan T. Hurt, MD, PhD, Neil E. Kay, MD, Sameer A. Parikh, MBBS, Sarah E. Baker, PhD, Zachary A. Buchholtz, BS, Matthew R. Buras, BS, Andrew J. Clayburn, BS, Joshua J. Dennis, BS, Juan C. Diaz Soto, MD, Vitaly Herasevich, MD, PhD, Allan M. Klompas, MB, BCh, BAO, Katie L. Kunze, PhD, Kathryn F. Larson, MD, John R. Mills, PhD, Riley J. Regimbal, BS, Juan G. Ripoll, MD, Matthew A. Sexton, MD, John R.A. Shepherd, MD, James R. Stubbs, MD, Elitza S. Theel, PhD, Camille M. van Buskirk, MD, Noud van Helmond, MD, Matthew N.P. Vogt, MD, Emily R. Whelan, BS, Chad C. Wiggins, PhD, Jeffrey L. Winters, MD, Arturo Casadevall, MD, PhD, Michael J. Joyner, MD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 7, Iss 5, Pp 499-513 (2023)
Objective: To examine the association of COVID-19 convalescent plasma transfusion with mortality and the differences between subgroups in hospitalized patients with COVID-19. Patients and Methods: On October 26, 2022, a systematic search was performe
Externí odkaz:
https://doaj.org/article/dadeeaf646b74fc8991c25a417a35f18
Autor:
Maria George Elias, Angelico D. Aputen, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8252 (2024)
Chlorambucil-platinum(IV) prodrugs exhibit multi-mechanistic chemotherapeutic activity with promising anticancer potential. The platinum(II) precursors of the prodrugs have been previously found to induce changes in the microtubule cytoskeleton, spec
Externí odkaz:
https://doaj.org/article/2b4798a84a594134bd63ed251d1b3839
Autor:
Maria George Elias, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
Cancers, Vol 16, Iss 14, p 2544 (2024)
Development of resistance to cisplatin, oxaliplatin and carboplatin remains a challenge for their use as chemotherapies, particularly in breast and colorectal cancer. Here, we compare the anticancer effect of novel complexes [Pt(1,10-phenanthroline)(
Externí odkaz:
https://doaj.org/article/186b0f5a300b4f949cec83b190249c74
Publikováno v:
Geoscience Communication, Vol 6, Pp 39-43 (2023)
Art–science partnerships offer valuable opportunities to enhance inclusive engagement with research through collaborative creative practice. Here, we present two case studies of interdisciplinary approaches to contextualising environmental science
Externí odkaz:
https://doaj.org/article/0f16b179d49241478fcce0d3aab4b44a
Publikováno v:
Journal of Eating Disorders, Vol 11, Iss 1, Pp 1-6 (2023)
Abstract Clinical practice guidelines for anorexia nervosa (AN) and atypical anorexia nervosa recommend treatment from a team including a mental health professional and a dietitian. To date, however, AN treatment models such as Enhanced Cognitive Beh
Externí odkaz:
https://doaj.org/article/91dbd06fb93949d0a702490c96c03c45
Autor:
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2181 (2024)
Kinetically inert platinum(IV) complexes are a chemical strategy to overcome the impediments of standard platinum(II) antineoplastic drugs like cisplatin, oxaliplatin and carboplatin. In this study, we reported the syntheses and structural characteri
Externí odkaz:
https://doaj.org/article/895f80b1275247969fe711f6d4a6beef
Autor:
Wolfgang Koenig, Kausik K. Ray, Ulf Landmesser, Lawrence A. Leiter, Gregory G. Schwartz, R. Scott Wright, Lorena Garcia Conde, Jackie Han, Frederick J. Raal
Publikováno v:
American Journal of Preventive Cardiology, Vol 14, Iss , Pp 100503- (2023)
Patients with cerebrovascular disease (CeVD) have been shown to benefit from lipid-lowering therapies, but guideline-recommended levels of low-density lipoprotein cholesterol (LDL-C) are often not attained with statin treatment alone. The ORION-9, OR
Externí odkaz:
https://doaj.org/article/17972f0d39ca43feb599af064db33e6b
Autor:
Brondwyn S. McGhie, Jennette Sakoff, Jayne Gilbert, Christopher P. Gordon, Janice R. Aldrich-Wright
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17150 (2023)
Cisplatin-type covalent chemotherapeutics are a cornerstone of modern medicinal oncology. However, these drugs remain encumbered with dose-limiting side effects and are susceptible to innate and acquired resistance. The bulk of platinum anticancer re
Externí odkaz:
https://doaj.org/article/b8f63d27175a43749bf094451be08f48