Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R. P. Fayngersh"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 271:H1900-H1906
Our previous studies on the mechanism of relaxation of calf pulmonary arteries to H2O2 detected a role for increased formation of guanosine-3',5'-cyclic monophosphate as a result of a catalase-elicited activation of soluble guanylate cyclase. We have
Autor:
Jie Wang, Weiqun Shen, Michael H. Gewitz, Hatim A. Omar, R. P. Fayngersh, Rajamma Mathew, Thomas H. Hintze, Michael S. Wolin
Publikováno v:
British Journal of Pharmacology. 118:1886-1890
1. Pacing-induced congestive heart failure (CHF) in dogs is associated with increased plasma levels of atrial natriuretic factor (ANF) and inhibition of receptor-mediated cyclic AMP-dependent relaxation in isolated pulmonary arteries (PA). Since ANF
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 270:H1044-H1053
Our previous studies in isolated endothelium-removed calf pulmonary arteries suggest that PO2-elicited responses are primarily mediated through modulation of guanosine 3',5'-cyclic monophosphate via changes in the generation of H2O2 originating from
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 269:L637-L644
Our laboratory has previously reported evidence that tone responses of isolated endothelium-removed calf pulmonary arteries elicited by changes in PO2 appear to be mediated via changes in H2O2 and guanosine 3',5'-cyclic monophosphate, and that the PO
Autor:
Kirkwood A. Pritchard, Pawel M. Kaminski, Michael S. Wolin, Mingdan Wu, Thomas H. Hintze, R. P. Fayngersh
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 266:H2108-H2113
Peroxynitrite (ONOO-) is an inflammatory cell-derived oxidant, formed by the reaction of superoxide anion (O2-) with nitric oxide (NO), which was recently reported to relax vascular tissues. In the present study, the potential role of NO in the mecha
Autor:
R. P. Fayngersh, Edilberto Martinez, Michael S. Wolin, Kamal M. Mohazzab-H., Reinaldo Figueroa, Nergesh Tejani
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 278(3)
We determined whether alterations in the mechanism of relaxation to H2O2potentially contribute to the enhanced prostaglandin-mediated contractile response to H2O2and posthypoxic reoxygenation seen in human placental vessels of pregnancies with gestat
Publikováno v:
Biochemistry. Biokhimiia. 63(7)
Nitric oxide has several signalling mechanisms that can potentially control force generation by vascular smooth muscle. Some of these mechanisms include the stimulation of cGMP production by the soluble heme-containing form of guanylate cyclase (sGC)
Publikováno v:
The American journal of physiology. 273(1 Pt 1)
We have recently reported in normal isolated-perfused rat lungs that low basal tone appears to be regulated by nitric oxide (NO)-dependent and -independent mechanisms of soluble guanylate cyclase activation. In this study, we examined the role of NO
Autor:
Michael S. Wolin, Reinaldo Figueroa, Edilberto Martinez, Nergesh Tejani, Hatim A. Omar, Hong Jiang, R. P. Fayngersh
Publikováno v:
American journal of obstetrics and gynecology. 173(6)
OBJECTIVE: Our objective was to determine whether the observed relaxation to lactate and other agents in placental vessels of normal pregnancies is altered in severe preeclampsia. STUDY DESIGN: Isolated placental arteries and veins from women with se