Zobrazeno 1 - 10
of 240
pro vyhledávání: '"R. Ostroff"'
Autor:
Duy Hoang, Kelly Flanagan, Qian Ding, Nicholas R Cazeault, Hanchen Li, Stefani Díaz-Valerio, Florentina Rus, Esther A Darfour, Elizabeth Kass, Katherine H Petersson, Martin K Nielsen, Heiko Liesegang, Gary R Ostroff, Raffi V Aroian
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 10, p e0012611 (2024)
Bacillus thuringiensis crystal (Cry) proteins have been expressed in commercial transgenic crops for nearly 30 years, providing safe and effective control of insect pests and significantly reducing the application of hazardous chemical pesticides. B.
Externí odkaz:
https://doaj.org/article/9cc6b4fce9dc4ecbb0b051409de584d2
Publikováno v:
International Journal of Infectious Diseases, Vol 21, Iss S1, p 365 (2014)
Externí odkaz:
https://doaj.org/article/eb8513f145dc425cb011bb4460cd6e3c
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 8, p 203 (2024)
Addressing the growing problem of antifungal resistance in medicine and agriculture requires the development of new drugs and strategies to preserve the efficacy of existing fungicides. One approach is to utilize delivery technologies. Yeast particle
Externí odkaz:
https://doaj.org/article/dd928a80cdad480f9fd0d23ea4be15e0
Autor:
Ruiying Wang, Lorena V. N. Oliveira, Diana Lourenco, Christina L. Gomez, Chrono K. Lee, Maureen M. Hester, Zhongming Mou, Gary R. Ostroff, Charles A. Specht, Stuart M. Levitz
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Vaccination with glucan particles (GP) containing the Cryptococcus neoformans chitin deacetylases Cda1 and Cda2 protect mice against experimental cryptococcosis. Here, immunological correlates of vaccine-mediated protection were explored. St
Externí odkaz:
https://doaj.org/article/2abf535f6ab94b949746239e52eee480
Autor:
Althea Campuzano, Komali Devi Pentakota, Yu-Rou Liao, Hao Zhang, Nathan P. Wiederhold, Gary R. Ostroff, Chiung-Yu Hung
Publikováno v:
Vaccines, Vol 12, Iss 1, p 67 (2024)
Coccidioidomycosis is caused by Coccidioides posadasii (Cp) and Coccidioides immitis (Ci), which have a 4–5% difference in their genomic sequences. There is an urgent need to develop a human vaccine against both species. A previously created recomb
Externí odkaz:
https://doaj.org/article/59b8eb324c154a17b135be77a031f270
Autor:
Maureen M. Hester, Lorena V. N. Oliveira, Ruiying Wang, Zhongming Mou, Diana Lourenco, Gary R. Ostroff, Charles A. Specht, Stuart M. Levitz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Meningitis due to the fungal pathogen Cryptococcus neoformans is estimated to cause nearly 200,000 deaths annually, mostly in resource-limited regions. We previously identified cryptococcal protein antigens which, when delivered in glucan particles,
Externí odkaz:
https://doaj.org/article/dd5f51e1e83046fa9dabdc899f222182
Autor:
Jeffrey Chicca, Nicholas R. Cazeault, Florentina Rus, Ambily Abraham, Carli Garceau, Hanchen Li, Samar M. Atwa, Kelly Flanagan, Ernesto R. Soto, Mary S. Morrison, David Gazzola, Yan Hu, David R. Liu, Martin K. Nielsen, Joseph F. Urban, Gary R. Ostroff, Raffi V. Aroian
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Bacillus thuringiensis (Bt) is a Gram-positive soil bacterium that is widely and safely applied in the environment as an insecticide for combatting insect pests that damage crops or are disease vectors. Dominant active ingredients made by Bt
Externí odkaz:
https://doaj.org/article/65e8549f2406471c93117803135a9cff
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1390 (2023)
Glucan particles (GPs) are hollow, porous 3–5 µm microspheres derived from the cell walls of Baker’s yeast (Saccharomyces cerevisiae). Their 1,3-β-glucan outer shell allows for receptor-mediated uptake by macrophages and other phagocytic innate
Externí odkaz:
https://doaj.org/article/4d571a25c09b4c1389e9329789a03181
Autor:
John Sanders, Yue Xie, David Gazzola, Hanchen Li, Ambily Abraham, Kelly Flanagan, Florentina Rus, Melanie Miller, Yan Hu, Sierra Guynn, Austin Draper, Sridhar Vakalapudi, Katherine H. Petersson, Dante Zarlenga, Robert W. Li, Joseph F. Urban, Jr., Gary R. Ostroff, Anne Zajac, Raffi V. Aroian
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 230-236 (2020)
Haemonchus contortus is a critical parasite of goats and sheep. Infection by this blood-feeding gastrointestinal nematode (GIN) parasite has significant health consequences, especially in lambs and kids. The parasite has developed resistance to virtu
Externí odkaz:
https://doaj.org/article/4751d03fa2fd4a1db37f9678292b3db2
Autor:
Charles A. Specht, E. Jane Homan, Chrono K. Lee, Zhongming Mou, Christina L. Gomez, Maureen M. Hester, Ambily Abraham, Florentina Rus, Gary R. Ostroff, Stuart M. Levitz
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The high global burden of cryptococcosis has made development of a protective vaccine a public health priority. We previously demonstrated that a vaccine composed of recombinant Cryptococcus neoformans chitin deacetylase 2 (Cda2) delivered i
Externí odkaz:
https://doaj.org/article/1a6114f4299c4ca8a075e43864d1b9ee