Výsledky vyhledávání - "R. O. Shcherbyna"

Akademický článek

Computer prediction of toxicity of new S-alkyl derivatives of 1,2,4-triazole

Autor: V. V. Kalchenko, R. O. Shcherbyna

Publikováno v: Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 17, Iss 3, Pp 253-256 (2024)

1,2,4-Triazole derivatives are of researchers’ significant interest due to their diverse biological properties, such as antimicrobial, anti-inflammatory, anticancer, and antioxidant activities. The integration of a 2-bromo-4-fluorophenyl fragment i

Externí odkaz: https://doaj.org/article/060c189e08514e7aae895efdee0673d5

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Akademický článek

QSAR prediction of toxicity for a new 1,2,4-triazole derivatives with 2-bromo-5-methoxyphenyl fragment

Autor: M. P. Skoryi, R. O. Shcherbyna

Publikováno v: Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 17, Iss 3, Pp 226-230 (2024)

New derivatives of 1,2,4-triazole are promising research targets due to their unique biological properties, including antimicrobial, antifungal, antitumor, and antioxidant activities. The introduction of the 2-bromo-5-methoxyphenyl fragment into the

Externí odkaz: https://doaj.org/article/6941a5f4d1bc4a2bbb122bac4b8231a0

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Akademický článek

Development of the optimal composition of tablets with the active substance potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio)acetate. Message 1. Study of the effect of auxiliary substances on bulk density, bulk density after shrinkage, fluidity and angle of natural slope of powder masses

Autor: R. O. Shcherbyna, O. V. Khromylova, H. R. Nimenko, V. O. Salionov

Publikováno v: Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, Vol 17, Iss 2 (2024)

The pharmaceutical industry continually evolves to meet the demands of modern society for high-quality medications. One avenue of this advancement involves exploring new technologies for manufacturing tablet formulations that adhere to contemporary q

Externí odkaz: https://doaj.org/article/acb7ce2b92b342a68c1a20a7e44aba1d

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Akademický článek

Clinical and prognostic value of parameters of cytokine regulation in oxygen-dependent patients with the coronavirus disease COVID-19

Autor: O. V. Riabokon, V. V. Cherkaskyi, Yu. Yu. Riabokon, R. O. Shcherbyna

Publikováno v: Patologìâ, Vol 20, Iss 2, Pp 126-134 (2023)

Aim of the work is to find out the clinical and prognostic significance of cytokine regulation parameters in oxygen-dependent patients with COVID-19 coronavirus disease in dynamics of the disease. Material and methods. 78 oxygen-dependent patients

Externí odkaz: https://doaj.org/article/b6ee42c0814243829df12ffe0392aa2d

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Akademický článek

Diagnostic values of MMP-9 and TGF-1β in assessing the severity of liver fibrosis and the rate of its progression in patients with chronic hepatitis C GT 1 infection

Autor: H. V. Venytska, O. V. Riabokon, Yu. Yu. Riabokon, R. O. Shcherbyna

Publikováno v: Zaporožskij Medicinskij Žurnal, Vol 25, Iss 4, Pp 326-332 (2023)

Aim. The purpose of our work is to find out diagnostic values of serum MMP-9 and TGF-1β determination for assessing the severity of liver fibrosis and the rate of its progression in patients with chronic hepatitis C genotype 1 (CHC GT1) infection.

Externí odkaz: https://doaj.org/article/895807e2a566467499c26d876c4ec5a7

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Akademický článek

Histological study of potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazole-3-yl)thio)acetate (PKR-173) corrective influence on the chickens liver state in the condition of tetracycline hepatitis

Autor: R. O. Shcherbyna, Ye. V. Vashchyk

Publikováno v: Zaporožskij Medicinskij Žurnal, Iss 3, Pp 404-412 (2018)

Despite great scientific progress in the sphere of hepatoprotectors development during recent years, the issues of hepatocytes protection and regeneration is relevant enough. In this aspect derivatives of heterocyclic systems are of great interest, i

Externí odkaz: https://doaj.org/article/e9bb1f8bbeaf4feab664690d725ad7ab

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The study of 2-((3-R-4-R1-4H-1,2,4-triazole-5-yl)thio) acetic acid salts as growth stimulators of winter wheat sprouts

Autor: N. O. Khromykh, Yu. V. Lykholat, R. O. Shcherbyna, D. M. Danilchenko

Publikováno v: Vìsnik farmacìï. :61-65

Wheat is one of the most important and most widespread crop plants not only in Ukraine, but also in world agriculture in general. Wheat hybrids have many advantages, but seed production is a very complicated, high-tech and costly process. Derivatives

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7e7a909c107bf81c4440881406c6291
https://doi.org/10.24959/nphj.17.2155

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