Zobrazeno 1 - 10
of 37
pro vyhledávání: '"R. Nickander"'
Publikováno v:
Annual Review of Pharmacology and Toxicology. 19:469-490
Autor:
D M, Zimmerman, S E, Smits, M D, Hynes, B E, Cantrell, J D, Leander, L G, Mendelsohn, R, Nickander
Publikováno v:
Drug and Alcohol Dependence. 14:381-401
Picenadol is a unique opioid mixed agonist-antagonist analgesic currently under clinical evaluation. Structurally, picenadol is a 4-phenylpiperidine derivative and a racemic mixture whose mixed agonist-antagonist properties are a consequence of the d
Publikováno v:
Toxicology and Applied Pharmacology. 25:398-409
Tobramycin, an aminoglycoside antibiotic, has been administered to mice, rats, cats and dogs for toxicologic evaluation. The sc LD50 values in mice and rats were 441 and 969 mg/kg, respectively. Deaths were preceded by CNS depression and occurred wit
Publikováno v:
NIDA research monograph. 41
Autor:
R. Nickander, D. N. Benslay
Publikováno v:
Agents and actions. 12(3)
Benoxaprofen, a new nonsteroidal anti-inflammatory agent recently marketed as an an antirheumatic drug, has been reported to suppress leucocyte migration into inflammatory sites, possibly by its reported inhibition of leukotriene synthesis. Benoxapro
Publikováno v:
NIDA research monograph. 34
Autor:
D N, Benslay, R, Nickander
Publikováno v:
European journal of rheumatology and inflammation. 5(2)
The ability of benoxaprofen to suppress bone damage associated with adjuvant-induced arthritis in rats was studied radiographically over a 49-day period. Benoxaprofen was administered orally at a daily dose of 30 mg/kg. Treated and control groups of
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 200(1)
alpha-d-Propoxyphene and its principle metabolite, alpha-d-norpropoxyphene, were compared pharmacologically to establish their relative opioid profiles as defined by naloxone reversal. Propoxyphene exhibited opioid activity in the following tests: mo
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