Výsledky vyhledávání - "R. N. Skryma"

[Effect of neuroendocrine cell differentiation of the human prostatic neoplasm cell line LNCaP on the characteristics of volume-sensitive chloride content]

Autor: R M, Lazarenko, Iu M, Vitko, N Kh, Pohoriela, R N, Skryma, Ia M, Shuba

Publikováno v: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). 49(6)

By means of patch-clamp technique we examined changes in volume-regulated chloride current (ICl,swell) at neuroendocrine differentiation of androgen-dependent LNCaP prostate cancer cells. In those cells with neuroendocrine differentiation resulted fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::832d3170e16a3282c61c374b9517ea26
https://pubmed.ncbi.nlm.nih.gov/14965032

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[Volume-sensitive anion conductivity in a human prostatic carcinoma cell line]

Autor: Ia M, Shuba, R N, Skryma, N B, Prevars'ka

Publikováno v: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). 45(4)

For the first time membrane anion current activated in response to the cell swelling following exposure to hypotonic solution has been found in human prostate carcinoma cell line LNCaP. The development of hypotonicity-evoked current required 5 to 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::97948a723034f49401a0d2bed4f6df3c
https://pubmed.ncbi.nlm.nih.gov/10474799

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Potassium conductance in the androgen-sensitive prostate cancer cell line, LNCaP: involvement in cell proliferation

Autor: R N, Skryma, N B, Prevarskaya, L, Dufy-Barbe, M F, Odessa, J, Audin, B, Dufy

Publikováno v: The Prostate. 33(2)

Very little is known about the expression of ion channels in prostate cells (both normal and malignant), and their possible role in physiological and pathological functions. We therefore studied ion conductances and their role in the proliferation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4d3efbe7a7579440231f0c9d78a3cda0
https://pubmed.ncbi.nlm.nih.gov/9316652

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Role of tyrosine phosphorylation in potassium channel activation. Functional association with prolactin receptor and JAK2 tyrosine kinase

Autor: N B, Prevarskaya, R N, Skryma, P, Vacher, N, Daniel, J, Djiane, B, Dufy

Publikováno v: The Journal of biological chemistry. 270(41)

Chinese hamster ovary (CHO) cells, stably transfected with the long form of the prolactin (PRL) receptor (PRL-R) cDNA, were used for PRL-R signal transduction studies. Patch-clamp technique in whole cell and cell-free configurations were employed. Ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d36a0b15f131e6df9f0ed8c86c1d15e7
https://pubmed.ncbi.nlm.nih.gov/7592639

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[Effects of short-term application of glutamate-containing solution on isolated rat hippocampal neurons]

Autor: V V, Rybal'chenko, N V, Prevarskaia, R N, Skryma, A I, Luĭk

Publikováno v: Neirofiziologiia = Neurophysiology. 24(4)

The "concentration clamp" technique has been modified to realize fast and short-term application of a transmitter to whole neuron followed by its fast washout. Prolonged glutamate application evoked activation of the desensitized current. The applica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3da58eaf9ef0667cdf21c5512eebcb7
https://pubmed.ncbi.nlm.nih.gov/1359433

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[Study of the recovery rate of non-NMDA desensitized receptors of hippocampal neurons using paired and rhythmic application of glutamate]

Autor: V V, Rybal'chenko, N B, Prevarskaia, R N, Skryma, A I, Luĭk

Publikováno v: Neirofiziologiia = Neurophysiology. 24(6)

The new technique has been used to realize paired short-term application of glutamate to whole dialyzed neuron. Desensitization of receptors via first application of glutamate resulted in incomplete recovery of the current evoked by the second applic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::381490ae157497e56439ae47cb5eb0de
https://pubmed.ncbi.nlm.nih.gov/1362975

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