Výsledky vyhledávání - "R. N. Mitchell"

CD8+ T cell subsets TC1 and TC2 cause different histopathologic forms of murine cardiac allograft rejection

Autor: M W, Delfs, Y, Furukawa, R N, Mitchell, A H, Lichtman

Publikováno v: Transplantation. 71(5)

CD4+ T cell effector function is sufficient to mediate allograft rejection, and it is suggested that CD8+ T cell-mediated effects are dependent on CD4+ T cell help. CD8+ T cells can be classified into at least two functional subsets: Tc1, producing h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46e2f938a98acfe27203c23a343e4206
https://pubmed.ncbi.nlm.nih.gov/11292288

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Association of B7-1 co-stimulation with the development of graft arterial disease. Studies using mice lacking B7-1, B7-2, or B7-1/B7-2

Autor: Y, Furukawa, D A, Mandelbrot, P, Libby, A H, Sharpe, R N, Mitchell

Publikováno v: The American journal of pathology. 157(2)

To investigate the roles of B7-1 and/or B7-2 co-stimulatory molecule in the development of graft arterial disease (GAD), major histocompatibility complex (MHC) class II-mismatched allograft hearts were transplanted into wild-type, B7-1(-/-), B7-2(-/-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a81eb6a2cac7ae38db5af16c08a68d1b
https://pubmed.ncbi.nlm.nih.gov/10934151

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Differential galactose alpha(1,3) galactose expression by porcine cardiac vascular endothelium

Autor: R H, Chen, R N, Mitchell, A, Kadner, D H, Adams

Publikováno v: Xenotransplantation. 6(3)

Galactose alpha(1,3) galactose (Gal) is the terminal carbohydrate moiety recognized by xenoreactive natural antibodies during hyperacute rejection (HAR). Binding of these antibodies in HAR triggers rapid microvascular thrombosis. We examined the dist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7f3f2775dadb8297332982c536a2d49
https://pubmed.ncbi.nlm.nih.gov/10503782

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Involvement of MIIC-like late endosomes in B cell receptor-mediated antigen processing in murine B cells

Autor: J R, Drake, T A, Lewis, K B, Condon, R N, Mitchell, P, Webster

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(2)

Currently, the involvement of classical vs novel endocytic compartments in the phenomenon of B cell receptor (BCR)-mediated Ag processing is a matter of considerable debate. In murine B cells, class II vesicles (CIIV) represent a novel endocytic comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::47b50667163486e5a30570f2b492637f
https://pubmed.ncbi.nlm.nih.gov/9916746

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Pattern of graft- and host-specific MHC class II expression in long-term murine cardiac allografts: origin of inflammatory and vascular wall cells

Autor: S, Hasegawa, G, Becker, H, Nagano, P, Libby, R N, Mitchell

Publikováno v: The American journal of pathology. 153(1)

In solid-tissue allografts, donor vascular cells as well as recipient inflammatory cells can express MHC class II molecules. However, it is uncertain how much residual donor endothelium persists and to what extent donor versus recipient MHC class II

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc58e5e6ce8914f4628880c6fd860053
https://pubmed.ncbi.nlm.nih.gov/9665467

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Coronary arteriosclerosis after T-cell-mediated injury in transplanted mouse hearts: role of interferon-gamma

Autor: H, Nagano, P, Libby, M K, Taylor, S, Hasegawa, J L, Stinn, G, Becker, N L, Tilney, R N, Mitchell

Publikováno v: The American journal of pathology. 152(5)

This study evaluated the contribution of acute parenchymal rejection and interferon (IFN)-gamma to the development of graft arterial disease (GAD) in totally allogeneic murine cardiac transplants. BALB/c (H-2d) hearts were transplanted into wild-type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b041d056ae27da969b8c6007aed2dd1
https://pubmed.ncbi.nlm.nih.gov/9588888

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CD40 and CD40 ligand (CD154) are coexpressed on microvessels in vivo in human cardiac allograft rejection

Autor: R M, Reul, J C, Fang, M D, Denton, C, Geehan, C, Long, R N, Mitchell, P, Ganz, D M, Briscoe

Publikováno v: Transplantation. 64(12)

CD40 is expressed by a wide variety of cells in the immune system, including endothelial cells. It binds to CD40 ligand ([CD40L] CD154), which was originally reported to be restricted in its expression to early-activated T cells. We report here the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4d93defdf7885ac166806f3d3b8e463a
https://pubmed.ncbi.nlm.nih.gov/9422418

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