Výsledky vyhledávání - "R. N. Mingaleeva"

Comparative analysis of herpes simplex virus thymidine kinase gene expression potentiation via HIV-1 Tat-TAR system and cancer-specific promoters in P53(+) and P53(-) cells

Autor: A. V. Sass, E. P. Kopantzev, R. N. Mingaleeva, Eugene D. Sverdlov, Igor P. Chernov, L. L. Zavalova

Publikováno v: Molecular Biology. 44:448-453

Tumor-specific promoters are predominantly active and ensure expression of the gene under control exclusively in cancer cells. However, low activity of the promoters is an essential disadvantage for their therapy usage. To achieve a higher expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0fc6fc7ad9a9ad9c6a91fba0e63436f3
https://doi.org/10.1134/s0026893310030131

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Study of transactivation effect on transcription by Tat-TAR system of human immunodeficiency virus type I (HIV-I) in nonlymphoid cells HEK293 and Calu-1

Autor: E. A. Stukacheva, Eugene D. Sverdlov, Igor P. Chernov, R. N. Mingaleeva, E. P. Kopantsev, N. V. Skaptseva

Publikováno v: Molecular Genetics, Microbiology and Virology. 24:56-60

An important problem in the development of gene therapy approaches in oncology is the necessity of using promoters that provide specific and high levels of gene expression in tumor cells. To solve this problem, we used an inducible system of gene exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ddda92a20bf5e3f80dca05e219dfd01
https://doi.org/10.3103/s0891416809020025

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[Comparative analysis of herpes simplex virus thymidine kinase gene expression potentiation via HIV-1 Tat-TAR-system and cancer-specific promoters in p53(+) and p53(-) cells]

Autor: R N, Mingaleeva, I P, Chernov, E P, Kopantsev, L L, Zavalova, A V, Sass, E D, Sverdlov

Publikováno v: Molekuliarnaia biologiia. 44(3)

Tumor-specific promoters are predominantly active and ensure expression of the gene under control exclusively in cancer cells. However, a low activity of the promoters is an essential disadvantage for their therapy usage. To achieve a higher expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6eb07f2985a67b310542a7b5e43ba06
https://pubmed.ncbi.nlm.nih.gov/20608175

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[Study of transactivation effect on transcription by Tat-TAR-system of human immunodeficiency virus type 1 (HIV-1) in non-lymphoid cells HEK293 and Calu-1]

Autor: R N, Mingaleeva, I P, Chernov, E P, Kopantsev, E A, Stukacheva, N V, Skaptsova, E D, Sverdlov

Publikováno v: Molekuliarnaia genetika, mikrobiologiia i virusologiia. (2)

An important problem in the development of gene therapy approaches in oncology is the necessity of using promoters providing specific and high level of gene expression in tumor cells. To solve this problem, we used inducible system of gene expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9493c825328af5124f9e03a08cadfe52
https://pubmed.ncbi.nlm.nih.gov/19517804

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