Zobrazeno 1 - 10
of 32
pro vyhledávání: '"R. N. Frank"'
Publikováno v:
Ophthalmology. 108:2266-2272
This study investigated whether the growth hormone receptor antagonist pegvisomant could produce regression of diabetic retinal neovascularization.A prospective, single-group, open-label, phase IIa multicenter trial was conducted.Twenty-five patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dae5d4e33a687d2bf345ff61777363
https://doi.org/10.1016/s0161-6420(01)00853-3
https://doi.org/10.1016/s0161-6420(01)00853-3
Autor:
R N Frank
This presentation covers two topics. First is a basic laboratory study, designed to explore the mechanism for the phenomenon of ‘early worsening,' in which individuals with type 1 diabetes and early to moderate retinopathy are rapidly placed on ‘
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e305aa56ba03c53c87130208b6c253
https://europepmc.org/articles/PMC3178307/
https://europepmc.org/articles/PMC3178307/
Autor:
Steven Szymkiewicz, Iwona Cygankiewicz, R N Anke Wollbrueck, R N Frank Buhtz, Ulf Meltendorf, Arthur J. Moss, Christian Jons, Wojciech Zareba, Jan Smid, Sebastian Kuss, Sven Reek, Helmut U. Klein
Publikováno v:
Pacing and clinical electrophysiology : PACE. 33(3)
The implantable cardioverter defibrillator (ICD) is able to reduce sudden arrhythmic death in patients who are considered to be at high risk. However, the arrhythmic risk may be increased only temporarily as long as the proarrhythmic conditions persi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66f5f79d1778e26ed95601bdcaeed15
https://pubmed.ncbi.nlm.nih.gov/19889186
https://pubmed.ncbi.nlm.nih.gov/19889186
Publikováno v:
Transactions of the American Ophthalmological Society. 98
PURPOSE: While most observers agree that age-related macular degeneration (AMD) is much more common in white persons than in persons of black African ancestry, the influence of iris color has been more controversial. We reexamined relationships betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10de861db1b15135d141264629500a9c
https://pubmed.ncbi.nlm.nih.gov/11190014
https://pubmed.ncbi.nlm.nih.gov/11190014
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To test the hypothesis that pathophysiological levels of glucose regulate aldose reductase (AR2) gene expression, protein production, and activity in human retinal pigment epithelial (RPE) cells in vitro.Primary cultures of human RPE cells were grown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db23a6237ffdd1a3bebae5933116e801
https://pubmed.ncbi.nlm.nih.gov/10798676
https://pubmed.ncbi.nlm.nih.gov/10798676
Publikováno v:
Investigative ophthalmologyvisual science. 40(9)
Determining which patients are at risk for the development of diabetic retinopathy is expected to greatly improve existing prevention and treatment options. In this study, using an animal model of diabetic retinopathy, the hypothesis was tested that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afca1fadb4052dc5091461207f8a3e78
https://pubmed.ncbi.nlm.nih.gov/10440266
https://pubmed.ncbi.nlm.nih.gov/10440266
Publikováno v:
American journal of ophthalmology. 127(6)
To test the hypothesis that neovascular age-related macular degeneration is related to oxidative stress involving the macular retinal pigment epithelium. This study investigated, as a function of age, levels of enzymes that defend tissues against oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::998ce7a27b9048755c46ab78be62c0ec
https://pubmed.ncbi.nlm.nih.gov/10372880
https://pubmed.ncbi.nlm.nih.gov/10372880
Publikováno v:
Investigative ophthalmologyvisual science. 38(1)
To determine whether vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), which have been implicated in the development of retinal and choroidal neovascularization, are present in the retinas and optic nerves of patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21b336c0a895aa558ea36e0a0b4f4cb0
https://pubmed.ncbi.nlm.nih.gov/9008628
https://pubmed.ncbi.nlm.nih.gov/9008628
Publikováno v:
Investigative ophthalmologyvisual science. 35(8)
Because several polypeptide growth factors are known to influence capillary endothelial cell mitogenesis, the authors investigated the presence of some of these molecules in choroidal neovascular membranes (CNVMs) removed surgically from human subjec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87afdd51cd8e7383beb906e297a90013
https://pubmed.ncbi.nlm.nih.gov/7519180
https://pubmed.ncbi.nlm.nih.gov/7519180
Publikováno v:
Investigative ophthalmologyvisual science. 34(8)
Polypeptide growth factors, such as the acidic and basic fibroblast growth factors (aFGF and bFGF), may be important in the pathogenesis of subretinal neovascularization. The authors studied the relationship of aFGF and bFGF expression to retinal pig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adfd1b427b1468dba061a266ac1aabf1
https://pubmed.ncbi.nlm.nih.gov/8325749
https://pubmed.ncbi.nlm.nih.gov/8325749