Zobrazeno 1 - 10
of 17
pro vyhledávání: '"R. Mitchell Baldwin"'
Autor:
Alan Morettin, Geneviève Paris, Younes Bouzid, R. Mitchell Baldwin, Theresa J. Falls, John C. Bell, Jocelyn Côté
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Tudor domain containing protein 3 (TDRD3) is a modular protein identified based on its ability to recognize methylated arginine motifs through its Tudor domain. We have previously shown that TDRD3 localizes to cytoplasmic stress granules, a
Externí odkaz:
https://doaj.org/article/b3d5a9fb36324400b4cbf9271ff6ea12
Autor:
Jean-Yves Masson, Alan Morettin, Laura Trinkle-Mulcahy, R. Mitchell Baldwin, Haben Tesfu Dawit, Hemanta Adhikary, Jocelyn Côté, Nasim Haghandish, Rachid Mazroui
Publikováno v:
Molecular Biology of the Cell
Protein arginine methyltransferases (PRMTs) are a family of enzymes that modify proteins by methylating the guanidino nitrogen atoms of arginine residues to regulate cellular processes such as chromatin remodeling, pre-mRNA splicing, and signal trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccb84ef914848080b8bf420466675b9
https://doi.org/10.1091/mbc.e18-05-0330
https://doi.org/10.1091/mbc.e18-05-0330
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2130 (2008)
The signaling pathways that may modulate the pathogenesis of diseases induced by expanded polyglutamine proteins are not well understood.Herein we demonstrate that expanded polyglutamine protein cytotoxicity is mediated primarily through activation o
Externí odkaz:
https://doaj.org/article/ad94c4a9d94048d2bce1d708c0b8826b
Autor:
Andréanne Didillon, Bernard J. Jasmin, Emma Bondy-Chorney, R. Mitchell Baldwin, Jocelyn Côté, Benoit Chabot
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 91:124-135
Aberrant expression of Protein Arginine Methyltransferases (PRMTs) has been observed in several cancer types, including breast cancer. We previously reported that the PRMT1v2 isoform, which is generated through inclusion of alternative exon 2, is ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac45fc25befc9c02b606681ebac4e92e
https://doi.org/10.1016/j.biocel.2017.07.008
https://doi.org/10.1016/j.biocel.2017.07.008
Publikováno v:
PROTEOMICS. 15:2187-2197
Arginine methylation is catalyzed by a family of enzymes called protein arginine methyltransferases (PRMTs). The PRMT1 gene generates at least seven distinct alternatively spliced isoforms (PRMT v1-v7), which together contribute a significant portion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31d004c8f37ed6bbb3900e1612d958d
https://doi.org/10.1002/pmic.201400209
https://doi.org/10.1002/pmic.201400209
Autor:
John C. Bell, R. Mitchell Baldwin, Geneviève Paris, Alan Morettin, Theresa Falls, Jocelyn Côté, Younes Bouzid
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Tudor domain containing protein 3 (TDRD3) is a modular protein identified based on its ability to recognize methylated arginine motifs through its Tudor domain. We have previously shown that TDRD3 localizes to cytoplasmic stress granules, a structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5c0f14aab36dbd96c22d34523df660
https://doi.org/10.1038/s41598-017-04955-4
https://doi.org/10.1038/s41598-017-04955-4
Autor:
Huishan, Guo, Maneka, Chitiprolu, Luc, Roncevic, Charlotte, Javalet, Fiona J, Hemming, My Tran, Trung, Lingrui, Meng, Elyse, Latreille, Christiano, Tanese de Souza, Danielle, McCulloch, R Mitchell, Baldwin, Rebecca, Auer, Jocelyn, Côté, Ryan Charles, Russell, Rémy, Sadoul, Derrick, Gibbings
Publikováno v:
Developmental cell. 43(6)
Autophagy and autophagy-related genes (Atg) have been attributed prominent roles in tumorigenesis, tumor growth, and metastasis. Extracellular vesicles called exosomes are also implicated in cancer metastasis. Here, we demonstrate that exosome produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74e450ddcc42d32b9dae4e7607552923
https://pubmed.ncbi.nlm.nih.gov/29257951
https://pubmed.ncbi.nlm.nih.gov/29257951
Publikováno v:
Mutagenesis. 30(2)
Breast cancer is the most commonly diagnosed female cancer in the world. Though therapeutic treatments are available to treat breast cancer and in some instances are successful, the occurrence of unsuccessful treatment, or the rate of tumour recurren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa8e2ebbe15ca036ea5584a5f911832
https://pubmed.ncbi.nlm.nih.gov/25688111
https://pubmed.ncbi.nlm.nih.gov/25688111
Publikováno v:
Oncogene. 22:853-857
Elevated levels of insulin-like growth factor (IGF)-II are associated with a poor prognosis in human pulmonary adenocarcinoma; however, a causal role for IGF-II in pulmonary adenocarcinoma has not been demonstrated. Here, we show that transgenic over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c235395b8f4587a35e5077adc48f01
https://doi.org/10.1038/sj.onc.1206188
https://doi.org/10.1038/sj.onc.1206188
Publikováno v:
World journal of biological chemistry. 5(2)
Protein arginine methyltransferases (PRMTs) catalyze the methylation of a variety of protein substrates, many of which have been linked to the development, progression and aggressiveness of different types of cancer. Moreover, aberrant expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d0180ca5d6e5ac36cfff7008dd8a27c
https://pubmed.ncbi.nlm.nih.gov/24921003
https://pubmed.ncbi.nlm.nih.gov/24921003