Zobrazeno 1 - 10
of 144
pro vyhledávání: '"R. Miedema"'
Autor:
Jelle R. Miedema, Lieke J. de Jong, Vivienne Kahlmann, Ingrid M. Bergen, Caroline E. Broos, Marlies S. Wijsenbeek, Rudi W. Hendriks, Odilia B. J. Corneth
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background The treatment response to corticosteroids in patients with sarcoidosis is highly variable. CD4+ T cells are central in sarcoid pathogenesis and their phenotype in peripheral blood (PB) associates with disease course. We hypothesiz
Externí odkaz:
https://doaj.org/article/dff29a9ed1ac42d8b0a4d358ec5f44f2
Autor:
Jaume Bordas-Martinez, Jelle R. Miedema, Bas J. Mathot, Leonard Seghers, Robert-Jan H. Galjaard, Marc H.G.P. Raaijmakers, Anna M. Aalbers, Marlies Wijsenbeek, Maria Molina-Molina, Merel E. Hellemons
Publikováno v:
JHLT Open, Vol 3, Iss , Pp 100054- (2024)
Background: Lung transplantation (LTX) is the last life-extending option for patients with progressive fibrosing interstitial lung diseases (fILD). Between 12% and 71% of patients with fILD are patients with underlying telomere-dysfunction (trILD) re
Externí odkaz:
https://doaj.org/article/83dbe04f966444c98e3206f5255ffa14
Autor:
Jelle R. Miedema, Matthijs L. Janssen, Jan von der Thüsen, Henrik Endeman, Anton W. Langerak, Merel E. Hellemons, Els van Nood, Bas W. A. Peeters, Sara J. Baart, Marco W. J. Schreurs
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIncreased titers of autoantibodies targeting the G-protein-coupled receptors angiotensin II type 1 receptor (AT1R) and endotelin-1 type A receptor (ETAR) are associated with severe coronavirus disease 2019 (COVID-19) infection. The aim of t
Externí odkaz:
https://doaj.org/article/5501f589f5ac42268f103cfaa3443a8c
Autor:
Jelle R. Miedema, Catharina C. Moor, Marcel Veltkamp, Sara Baart, Natascha S. L. Lie, Jan C. Grutters, Marlies S. Wijsenbeek, Rémy L. M. Mostard
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-6 (2022)
Abstract Background Pirfenidone slows down disease progression in idiopathic pulmonary fibrosis (IPF). Recent studies suggest a treatment effect in progressive pulmonary fibrosis other than IPF. However, the safety and effectiveness of pirfenidone in
Externí odkaz:
https://doaj.org/article/c9a7d9f9f6c24148afb4b32c0839dc92
Publikováno v:
JAAD Case Reports, Vol 17, Iss , Pp 130-151 (2021)
Externí odkaz:
https://doaj.org/article/e316645bba514115aa5eb2c711929dbd
Publikováno v:
International Journal of Women's Dermatology, Vol 8, Iss 3, p e029 (2022)
Externí odkaz:
https://doaj.org/article/8e3fa203b000424a9a1e2a6323e8c033
Autor:
Annelies Verbon, Jelmer Alsma, Hester Lingsma, David M Kent, David van Klaveren, Rozemarijn L van Bruchem-Visser, Tom Dormans, Stephanie C E Schuit, Alexandros Rekkas, Rob J C G Verdonschot, Dick T J J Koning, Marlijn J A Kamps, Robert Stassen, Sebastiaan Weijer, Klaas-Sierk Arnold, Benjamin Tomlow, Hilde R H de Geus, Jelle R Miedema, Els van Nood
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Objectives Develop simple and valid models for predicting mortality and need for intensive care unit (ICU) admission in patients who present at the emergency department (ED) with suspected COVID-19.Design Retrospective.Setting Secondary care in four
Externí odkaz:
https://doaj.org/article/9d70e869cce4427698f00fbaa5ce28fb
Autor:
Peter Heukels, Jennifer A. C. van Hulst, Menno van Nimwegen, Carian E. Boorsma, Barbro N. Melgert, Jan H. von der Thusen, Bernt van den Blink, Rogier A. S. Hoek, Jelle R. Miedema, Stefan F. H. Neys, Odilia B. J. Corneth, Rudi W. Hendriks, Marlies S. Wijsenbeek, Mirjam Kool
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Rationale Idiopathic Pulmonary Fibrosis (IPF) is thought to be triggered by repeated alveolar epithelial cell injury. Current evidence suggests that aberrant immune activation may contribute. However, the role of B-cell activation remains un
Externí odkaz:
https://doaj.org/article/13715e292aad4ffcbe1f2d8589b1faa4
Autor:
C. C. Moor, M. Wapenaar, J. R. Miedema, J. J. M. Geelhoed, P. P. Chandoesing, M. S. Wijsenbeek
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-5 (2018)
Abstract In idiopathic pulmonary fibrosis (IPF), home monitoring experiences are limited, not yet real-time available nor implemented in daily care. We evaluated feasibility and potential barriers of a new home monitoring program with real-time wirel
Externí odkaz:
https://doaj.org/article/661f61f64f744856a727545747c30941
Autor:
Marjolein P M Hensgens, Eveline M Delemarre, Julia Drylewicz, Mareye Voortman, Roline M Krol, Virgil A S H Dalm, Jelle R Miedema, Ivo Wiertz, Jan Grutters, Maarten Limper, Stefan Nierkens, Helen L Leavis
Publikováno v:
Rheumatology (Oxford, England), 61(10), 4087-4096. Oxford University Press
Objectives The presence of melanoma differentiation-associated protein 5 (MDA5) antibodies in patients with DM is associated with the development of a rapidly progressive interstitial lung disease (RPILD), unresponsive to conventional treatment. We c