Zobrazeno 1 - 10
of 136
pro vyhledávání: '"R. Michael Van Dam"'
Autor:
Daniele Vinciguerra, Rajalakshmi P S, Jane Yang, Panagiotis G. Georgiou, Katherine Snell, Théo Pesenti, Jeffrey Collins, Mikayla Tamboline, Shili Xu, R. Michael van Dam, Kathryn M. M. Messina, Andrea L. Hevener, Heather D. Maynard
Publikováno v:
ACS Central Science, Vol 10, Iss 11, Pp 2036-2047 (2024)
Externí odkaz:
https://doaj.org/article/0c54b06039ce4440b2130fcca3f81581
Publikováno v:
Molecules, Vol 29, Iss 19, p 4572 (2024)
The radiometal gallium-68 (Ga-68) has garnered significant interest due to its convenient production via compact and widely available generators and the high performance of 68Ga-labeled compounds for positron-emission tomography (PET) imaging for can
Externí odkaz:
https://doaj.org/article/055fe68cc43740fbb9f590c34a112b30
Autor:
Alejandra Rios, Travis S. Holloway, Philip H. Chao, Christian De Caro, Chelsea C. Okoro, R. Michael van Dam
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The increasing number of positron-emission tomography (PET) tracers being developed to aid drug development and create new diagnostics has led to an increased need for radiosynthesis development and optimization. Current radiosynthesis instr
Externí odkaz:
https://doaj.org/article/027114849d054c1db96bcb1637291650
Autor:
Emerson Bernardes, Peter Caravan, R. Michael van Dam, Winnie Deuther-Conrad, Beverley Ellis, Shozo Furumoto, Benjamin Guillet, Ya-Yao Huang, Hongmei Jia, Peter Laverman, Zijing Li, Zhaofei Liu, Filippo Lodi, Yubin Miao, Lars Perk, Ralf Schirrmacher, Johnny Vercoullie, Hua Yang, Min Yang, Xing Yang, Junbo Zhang, Ming-Rong Zhang, Hua Zhu
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to update the readership on trends in the field of radiopharmaceutical development. Results This commentary of highlights has resul
Externí odkaz:
https://doaj.org/article/c5700f1006a6427595afeca427a323cc
Autor:
Ksenia Lisova, Jia Wang, Tibor Jacob Hajagos, Yingqing Lu, Alexander Hsiao, Arkadij Elizarov, R. Michael van Dam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Current equipment and methods for preparation of radiopharmaceuticals for positron emission tomography (PET) are expensive and best suited for large-scale multi-doses batches. Microfluidic radiosynthesizers have been shown to provide an econ
Externí odkaz:
https://doaj.org/article/ab7dd973bfc74e81a998420afb75274c
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-16 (2020)
Abstract Background Current automated radiosynthesizers are generally optimized for producing large batches of PET tracers. Preclinical imaging studies, however, often require only a small portion of a regular batch, which cannot be economically prod
Externí odkaz:
https://doaj.org/article/41d87cda5a4440de8c10cacbf7ebced2
Publikováno v:
Molecules, Vol 27, Iss 23, p 8178 (2022)
Before formulating radiopharmaceuticals for injection, it is necessary to remove various impurities via purification. Conventional synthesis methods involve relatively large quantities of reagents, requiring high-resolution and high-capacity chromato
Externí odkaz:
https://doaj.org/article/0a22bb8fb7f74cdab7c7e70408eba1a7
Autor:
Ksenia Lisova, Bao Ying Chen, Jia Wang, Kelly Mun-Ming Fong, Peter M. Clark, R. Michael van Dam
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-15 (2019)
Abstract Background Conventional scale production of small batches of PET tracers (e.g. for preclinical imaging) is an inefficient use of resources. Using O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET), we demonstrate that simple microvolume radiosynth
Externí odkaz:
https://doaj.org/article/b68e3a66adad4a99831d8381794d9d71
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Over the past several years there has been an explosion of interest in exploiting Cerenkov radiation to enable in vivo and intraoperative optical imaging of subjects injected with trace amounts of radiopharmaceuticals. At the same time, Cerenkov lumi
Externí odkaz:
https://doaj.org/article/9af901a2d404406a8d7ec3ffc4379d69
Autor:
Pei Yuin Keng, R. Michael van Dam
Publikováno v:
Molecular Imaging, Vol 14 (2015)
The emerging technology of digital microfluidics is opening up the possibility of performing radiochemistry at the microliter scale to produce tracers for positron emission tomography (PET) labeled with fluorine-18 or other isotopes. Working at this
Externí odkaz:
https://doaj.org/article/937ad0a8704641beb9e0c3fbc2489087