Zobrazeno 1 - 8
of 8
pro vyhledávání: '"R. Michael Sharrard"'
Publikováno v:
Cellular Signalling. 19:129-138
Protein Kinase B (PKB/Akt) is a key regulator of cell proliferation, motility and survival. The activation status of PKB is regulated by phosphatidylinositol 3-kinase (PI3K) via the synthesis of phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3,
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1494:282-285
The human tumour suppressor gene PTEN/MMAC1/TEP1 encodes a lipid and protein phosphatase. Using RT-PCR, alternatively spliced forms of PTEN mRNA, encoding full-length PTEN and two forms of the protein truncated at the C-terminal end, were detected in
Publikováno v:
The Journal of Pathology. 166:225-233
Aberrant expression of c-myc has been implicated in the development of colorectal carcinomas. We have used monoclonal antibodies 6E10 and 9E10, raised against mid-sequence and C-terminal peptides of the c-myc protein, to study the distribution of myc
Publikováno v:
Developmental biology. 299(2)
Cdx homeodomain transcription factors play important roles in the development of the vertebrate body axis and gut epithelium. Signaling involving FGF, wnt and retinoic acid ligands has been implicated in the regulation of individual Cdx genes. In thi
Publikováno v:
FEBS letters. 179(2)
Human synovial explants in culture release material that stimulates the production of prostaglandin E 2 (PGE 2 ) and several extracellular enzymes by human chondrocytes. Fractionation of conditioned medium by gel filtration revealed a protein of appr
Publikováno v:
Biochemical Society Transactions. 10:382-383
Autor:
Sheila MacNeil, Barry L. Brown, R. Michael Sharrard, S. Tomlinson, Lisa Cawood, Stanley S. Bleehen, Simon W. Walker
Publikováno v:
Biochemical Society Transactions. 11:359-360
Autor:
R. Michael Sharrard, Barry L. Brown, Sheila MacNeil, Simon W. Walker, S. Tomlinson, Stanley S. Bleehen
Publikováno v:
Biochemical Society Transactions. 11:360-360