Zobrazeno 1 - 10
of 146
pro vyhledávání: '"R. Michael Blaese"'
Publikováno v:
The journal of allergy and clinical immunology. In practice. 7(3)
Autor:
Fabio Candotti, Kit L. Shaw, Linda Muul, Denise Carbonaro, Robert Sokolic, Christopher Choi, Shepherd H. Schurman, Elizabeth Garabedian, Chimene Kesserwan, G. Jayashree Jagadeesh, Pei-Yu Fu, Eric Gschweng, Aaron Cooper, John F. Tisdale, Kenneth I. Weinberg, Gay M. Crooks, Neena Kapoor, Ami Shah, Hisham Abdel-Azim, Xiao-Jin Yu, Monika Smogorzewska, Alan S. Wayne, Howard M. Rosenblatt, Carla M. Davis, Celine Hanson, Radha G. Rishi, Xiaoyan Wang, David Gjertson, Otto O. Yang, Arumugam Balamurugan, Gerhard Bauer, Joanna A. Ireland, Barbara C. Engel, Gregory M. Podsakoff, Michael S. Hershfield, R. Michael Blaese, Robertson Parkman, Donald B. Kohn
Publikováno v:
Blood. 120:3635-3646
We conducted a gene therapy trial in 10 patients with adenosine deaminase (ADA)–deficient severe combined immunodeficiency using 2 slightly different retroviral vectors for the transduction of patients' bone marrow CD34+ cells. Four subjects were t
Autor:
Daniele Moratto, Qing Yan, Fabio Candotti, R. Michael Blaese, Linda M. Muul, Kumar Felix, Jacquelin H. Bui, Brian R. Davis, Nicole L. Prokopishyn
Publikováno v:
Clinical Immunology. 135:72-83
The reasons underlying the occurrence of multiple revertant genotypes in Wiskott-Aldrich syndrome (WAS) patients remain unclear. We have identified more than 30 revertant genotypes in a C995T WAS patient having 10-15% revertant, WAS protein (WASp)-ex
Autor:
Fabio Candotti, Linda M. Muul, Nicole L. Prokopishyn, Daniele Moratto, Michael DiCola, Brian R. Davis, Jonathan B. Rosenberg, R. Michael Blaese
Publikováno v:
Blood. 111:5064-5067
Spontaneous somatic reversions of inherited mutations are poorly understood phenomena that are thought to occur uncommonly in a variety of genetic disorders. When molecularly characterized, revertant cells have rarely exhibited more than one revertan
Autor:
R. Michael Blaese
Publikováno v:
Immunologic Research. 38:274-284
The efforts to find satisfactory treatments for seriously ill patients with primary immunodeficiency have resulted in the development of important new therapeutic procedures with benefits reaching far beyond the relatively small number of patients af
Autor:
Ryuya Yamanaka, Hitoshi Hasegawa, Kleanthis G. Xanthopoulos, Naoto Tsuchiya, Ryuichi Tanaka, Junpei Honma, Jay Ramsey, Naoki Yajima, R. Michael Blaese
Publikováno v:
Journal of Neurosurgery. 99:746-753
Object. The aim of this study was to investigate further immunogene treatment of malignant brain tumor to improve its therapeutic efficacy. Methods. Intratumoral dendritic cells pulsed with Semliki Forest virus (SFV)—interleukin-18 (IL-18) and/or s
Publikováno v:
Human Gene Therapy. 13:1605-1610
The first approved clinical gene therapy trial for adenosine deaminase (ADA) deficiency employed autologous T cells grown in fetal calf serum (FCS)-supplemented medium and transduced with a retroviral vector (LASN) also produced in the presence of FC
Autor:
Richard Hong, Stephen E. Miles, Steven M. Holland, Thomas A. Fleisher, Jennifer M. Puck, Francisco A. Bonilla, Mary Ellen Conley, William T. Shearer, Jerry A. Winkelstein, Kathleen E. Sullivan, Harry L. Malech, Ramsay Fuleihan, Howard M. Lederman, Erwin W. Gelfand, Rebecca H. Buckley, Jordan S. Orange, John M. Routes, Alexandra H. Filipovich, Troy R. Torgerson, Luigi D. Notarangelo, Mark Ballow, Charlotte Cunningham-Rundles, Zuhair K. Ballas, R. Michael Blaese, E. Richard Stiehm, Hans D. Ochs, Vivian Hernandez-Trujillo
Publikováno v:
Shearer, WT; Fleisher, TA; Buckley, RH; Ballas, Z; Ballow, M; Blaese, RM; et al.(2014). Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts. Journal of Allergy and Clinical Immunology, 133(4), 961-966. doi: 10.1016/j.jaci.2013.11.043. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/02n4q7t5
The present uncertainty of which live viral or bacterial vaccines can be given to immunodeficient patients and the growing neglect of societal adherence to routine immunizations has prompted the Medical Advisory Committee of the Immune Deficiency Fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1adb38e1445b8dfad840a71c70fa6bd
http://www.escholarship.org/uc/item/02n4q7t5
http://www.escholarship.org/uc/item/02n4q7t5
Autor:
Harry Ford, R. Michael Blaese, David A. Cooney, Riad Agbaria, James A. Kelley, Zhang Hao, David G. Johns, Fabio Candotti
Publikováno v:
Biochemical and Biophysical Research Communications. 289:525-530
A method is described for the preparation of ganciclovir triphosphate (GCV-TP) using murine colon cancer cells (MC38) transduced with the herpes simplex virus-thymidine kinase (MC38/HSV-tk). Murine cells transduced with viral-tk contain required vira
Autor:
Richard A. Morgan, Thomas G. Jensen, Daniel M. Sullivan, Lorne B. Taichman, R. Michael Blaese, Robert B. Nussenblatt, Karl G. Csaky
Publikováno v:
Human Gene Therapy. 8:2125-2132
Gyrate atrophy is a progressive blindness associated with deficiency of ornithine aminotransferase (OAT). The strategy of using an autologous keratinocyte graft, modified to express high levels of OAT as an ornithine-catabolizing skin-based enzyme si