Zobrazeno 1 - 10
of 57
pro vyhledávání: '"R. Mesirca"'
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 361:157-164
The ability of metalaxyl, whose mutagenic/cocarcinogenic activity has as yet not been clarified, to affect specific biomarkers related to non-genotoxic cocarcinogenesis, was investigated. Several CYP-dependent reactions have been studied in liver, ki
Publikováno v:
Chemico-Biological Interactions. 95:127-139
The induction of CYP2B1 mediated pentoxyresorufin O-dealkylase (PROD) activity by various xenobiotics was explored in liver, kidney and lung from a variety of animal species of both sexes, in order to gain insights into the substrate specificity of i
Autor:
Moreno Paolini, Giorgio Cantelli-Forti, Gian Luigi Biagi, Laura Pozzetti, A. Sapone, R. Mesirca, N. M. Trieff, E. Sapigni
Publikováno v:
Toxicological & Environmental Chemistry. 44:43-53
Using the highly sensitive probe‐substrate pentoxyresorufin towards cytochrome P450 2B1 isozymes, the relationship between the induction of this set of hemoproteins by barbiturates and toxicity was studied. Each chemical, allobarbital (AB), amobarb
Publikováno v:
Toxicological & Environmental Chemistry. 36:235-249
Thirteen halogenated hydrocarbons, 1,1,1,2‐tetrachloroethane (1,1,1,2‐TCE), 1,1,2,2‐tetrachloroethane (1,1,2,2‐TCE), pentachloroethane (PCE), 1,2‐dibromoethane (DBE), 1,1,2,2‐tetrabromoethane (1,1,2,2‐TBE), iodoethane (IE), 1,1‐dichlo
Autor:
Giorgio Cantelli-Forti, R. Mesirca, Moreno Paolini, Gian Luigi Biagi, N. Gialluca, Carlo Bauer
Publikováno v:
Carcinogenesis. 16:971-973
Autor:
Giorgio Cantelli-Forti, M. Mazzullo, Laura Pozzetti, Paolo Perocco, R. Mesirca, Andrea Sapone, Moreno Paolini
Publikováno v:
Cancer letters. 117(1)
The aim of this work was to study the ability of the organophosphate insecticide acephate to alter some biochemical markers of effect related non-genetic cocarcinogenesis. For this purpose, selective CYP-dependent reactions have been examined in live
Publikováno v:
Cancer letters. 113(1-2)
The ability of dithianon, whose mutagenic/cocarcinogenic activity has as yet not been clarified, to affect specific biomarkers of effect related to non-genotoxic cocarcinogenesis was investigated. For this purpose, several CYP-dependent reactions hav
Autor:
Laura Pozzetti, Moreno Paolini, F. Vigagni, R. Mesirca, Francesca Maffei, G. Cantelli Forti, Carmela Fimognari, Patrizia Hrelia
Publikováno v:
Scopus-Elsevier
The mutagenic/cocarcinogenic potential of the fungicide Vinclozolin was assessed by a comprehensive examination of toxicity mechanisms at both the genetic and the metabolic level. Vinclozolin did not induce any significant increase in chromosomal abe
Publikováno v:
Cancer letters. 101(2)
Selective biochemical markers of effect have been used to evaluate some non-genotoxic cocarcinogenic properties of Fenarimol. Several CYP-dependent reactions have been monitored in liver, kidney and lung microsomes of male and female Sprague-Dawely r
Publikováno v:
Archives of toxicology. 70(7)
This study aimed to investigate the effect of single and repeated administration of fenarimol on murine liver, kidney and lung microsomal CYP-catalyzed drug metabolism. The modulation of the regio- and stereo-selective hydroxylation of testosterone b