Zobrazeno 1 - 10
of 265
pro vyhledávání: '"R. Mcdevitt"'
Autor:
Matthias Miederer, Martina Benešová-Schäfer, Constantin Mamat, David Kästner, Marc Pretze, Enrico Michler, Claudia Brogsitter, Jörg Kotzerke, Klaus Kopka, David A. Scheinberg, Michael R. McDevitt
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 76 (2024)
The use of radionuclides for targeted endoradiotherapy is a rapidly growing field in oncology. In particular, the focus on the biological effects of different radiation qualities is an important factor in understanding and implementing new therapies.
Externí odkaz:
https://doaj.org/article/25291905b7a14e40b287668ad107995a
Autor:
Hanwen Zhang, Diane Abou, Peng Lu, Abbie Meghan Hasson, Alexandria Villmer, Nadia Benabdallah, Wen Jiang, David Ulmert, Sean Carlin, Buck E. Rogers, Norman F. Turtle, Michael R. McDevitt, Brian Baumann, Brian W. Simons, Farrokh Dehdashti, Dong Zhou, Daniel L. J. Thorek
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The growing interest and clinical translation of alpha particle (α) therapies brings with it new challenges to assess target cell engagement and to monitor therapeutic effect. Noninvasive imaging has great potential to guide α-treatment an
Externí odkaz:
https://doaj.org/article/9b792b047c414428bbbdfc607f1aa8a7
Autor:
Sam Wong, Simone Alidori, Barbara P. Mello, Bryan Aristega Almeida, David Ulmert, Matthew B. Brendel, David A. Scheinberg, Michael R. McDevitt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cellulose nanocrystals (CNC) are linear organic nanomaterials derived from an abundant naturally occurring biopolymer resource. Strategic modification of the primary and secondary hydroxyl groups on the CNC introduces amine and iodine group
Externí odkaz:
https://doaj.org/article/3ada09b285da4525900a0ed8147bb509
Autor:
Michael R. McDevitt, Daniel L. J. Thorek, Takeshi Hashimoto, Tatsuo Gondo, Darren R. Veach, Sai Kiran Sharma, Teja Muralidhar Kalidindi, Diane S. Abou, Philip A. Watson, Bradley J. Beattie, Oskar Vilhemsson Timmermand, Sven-Erik Strand, Jason S. Lewis, Peter T. Scardino, Howard I. Scher, Hans Lilja, Steven M. Larson, David Ulmert
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Radionuclides that emit alpha particles (charged helium nuclei) are currently used clinically to treat cancers including prostate cancer. Here, the authors combine a humanized antibody to an alpha particle emitter, specifically to target a downstream
Externí odkaz:
https://doaj.org/article/02a356c6cc14425c8da1a1e7764743bc
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
S1. Hierarchical clustering based on Euclidean distance of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and untreated (C1-3) samples.S2. Multi-dimensional scaling plot of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1377f5f545ae64255126d352d870e4e0
https://doi.org/10.1158/1541-7786.22551840
https://doi.org/10.1158/1541-7786.22551840
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
Noninvasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer therapies. AR is a critical driver and mediator of resistance of prostate cancer but currently available no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0445efa2285bf786789e370019ca125b
https://doi.org/10.1158/1541-7786.c.6534810
https://doi.org/10.1158/1541-7786.c.6534810
Autor:
Nai K. Cheung, Steven M. Larson, Charles M. Rudin, Adam O. Michel, Sebastien Monette, Pat B. Zanzonico, Hong-Fen Guo, Aiza A. Malik, Daniela Burnes Vargas, Mitesh Patel, Edward K. Fung, Darren R. Veach, Guangbin Yang, Ouathek Ouerfelli, Michael R. McDevitt, Mahiuddin Ahmed, Sarah M. Cheal, Brian H. Santich
summary of toxicity data from 177Lu SADA-PRIT experiment against a neuroblastoma cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2a500c84da628716428d8c988bb847
https://doi.org/10.1158/1078-0432.22479491
https://doi.org/10.1158/1078-0432.22479491
Autor:
David Ulmert, Daniel L.J. Thorek, Michael R. McDevitt, Hans Lilja, Steven M. Larson, Peter Scardino, Howard I. Scher, Dmitry Pankov, Nadia Benabdallah, Pat Zanzonico, Robert Damoiseaux, Mohamed Altai, Joanna Strand, Sven-Erik Strand, Teja Kalidindi, Urpo Lamminmäki, Christian von Bodman, Katharina Braun, Katharina Lückerath, Claire M. Storey, Darren R. Veach
Supplementary Figure S2. Autoradiography of whole mounted KLK3_Hi-MYC GEMM prostate sections obtained 120h p.i. of [89Zr]hu5A10 (A) or [90Y]hu5A10 (B). Radioimmunoconjugate activity was detected in regions expressing PSA, but not in adjacent tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6796d7061d299f00f689299fe6a1e311
https://doi.org/10.1158/1078-0432.22480926.v1
https://doi.org/10.1158/1078-0432.22480926.v1
Autor:
Nai K. Cheung, Steven M. Larson, Charles M. Rudin, Adam O. Michel, Sebastien Monette, Pat B. Zanzonico, Hong-Fen Guo, Aiza A. Malik, Daniela Burnes Vargas, Mitesh Patel, Edward K. Fung, Darren R. Veach, Guangbin Yang, Ouathek Ouerfelli, Michael R. McDevitt, Mahiuddin Ahmed, Sarah M. Cheal, Brian H. Santich
2-step SADA-PRIT imaging by PET/CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227c28b24bf83bfd1f7bde02d3209963
https://doi.org/10.1158/1078-0432.22479479.v1
https://doi.org/10.1158/1078-0432.22479479.v1
Autor:
David Ulmert, Daniel L.J. Thorek, Michael R. McDevitt, Hans Lilja, Steven M. Larson, Peter Scardino, Howard I. Scher, Dmitry Pankov, Nadia Benabdallah, Pat Zanzonico, Robert Damoiseaux, Mohamed Altai, Joanna Strand, Sven-Erik Strand, Teja Kalidindi, Urpo Lamminmäki, Christian von Bodman, Katharina Braun, Katharina Lückerath, Claire M. Storey, Darren R. Veach
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0347ffa75648b5075af7dcfff7ac6a64
https://doi.org/10.1158/1078-0432.22480914.v1
https://doi.org/10.1158/1078-0432.22480914.v1